Q9LDA7 (P2C39_ARATH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable protein phosphatase 2C 39
Short name=AtPP2C39
EC=3.1.3.16

Gene names

Ordered Locus Names:	At3g15260
ORF Names:	K7L4.6

Organism

Arabidopsis thaliana (Mouse-ear cress) [Reference proteome]

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	289 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	A phosphoprotein + H2O = a protein + phosphate.
Cofactor	Binds 2 magnesium or manganese ions per subunit By similarity.
Sequence similarities	Belongs to the PP2C family. Contains 1 PP2C-like domain.

Ontologies

Keywords
Ligand	Magnesium Manganese Metal-binding
Molecular function	Hydrolase Protein phosphatase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	metabolic process Inferred from electronic annotation. Source: GOC
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoprotein phosphatase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 289	289	Probable protein phosphatase 2C 39		PRO_0000367964
Regions
	Domain	40 – 281	242	PP2C-like
Sites
	Metal binding	78	1	Manganese 1 By similarity
	Metal binding	78	1	Manganese 2 By similarity
	Metal binding	79	1	Manganese 1; via carbonyl oxygen By similarity
	Metal binding	240	1	Manganese 2 By similarity
	Metal binding	279	1	Manganese 2 By similarity
Experimental info
	Sequence conflict	55	1	M → I in AAM53328. Ref.4

Sequences

	Sequence		Length	Mass (Da)
	Q9LDA7 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: D37C3DE3BF2F481B	FASTA	289	31,630
	10 20 30 40 50 60 MTGREILHKM KESVKEKVGL GASASSADSG KGKSKMLKQI THGFHLVKGK AFHEMEDYVV 70 80 90 100 110 120 AKFKEVDDNE LGLFAIFDGH LSHEIPDYLC SHLFENILKE PNFWQEPEKA IKKAYYITDT 130 140 150 160 170 180 TILDKADDLG KGGSTAVTAI LINCQKLVVA NVGDSRAVIC QNGVAKPLSV DHEPNMEKDE 190 200 210 220 230 240 IENRGGFVSN FPGDVPRVDG QLAVARAFGD KSLKMHLSSE PYVTVEIIDD DAEFLILASD 250 260 270 280 GLWKVMSNQE AVDSIKGIKD AKAAAKHLAE EAVARKSSDD ISVVVVKFQ

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC clones." Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S. DNA Res. 7:217-221(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[2]	The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia.
[3]	"Functional annotation of a full-length Arabidopsis cDNA collection." Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T., Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y., Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K., Shinagawa A., Shinozaki K. Science 296:141-145(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia.
[4]	"Empirical analysis of transcriptional activity in the Arabidopsis genome." Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R. Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia.
[5]	"Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis." Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y. BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract] Cited for: GENE FAMILY, NOMENCLATURE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP000413 Genomic DNA. Translation: BAB02155.1. CP002686 Genomic DNA. Translation: AEE75637.1. CP002686 Genomic DNA. Translation: AEE75638.1. AK117480 mRNA. Translation: BAC42144.1. AY120770 mRNA. Translation: AAM53328.1. BT008532 mRNA. Translation: AAP40359.1.
IPI	IPI00548411.
RefSeq	NP_188144.1. NM_112389.3. NP_974318.1. NM_202589.1.
UniGene	At.28162. At.64997.
3D structure databases
HSSP	HSSP built from PDB template 1A6Q based on UniProtKB P35813.
ProteinModelPortal	Q9LDA7.
SMR	Q9LDA7. Positions 54-289.
ModBase	Search...
Proteomic databases
PaxDb	Q9LDA7.
PRIDE	Q9LDA7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	AT3G15260.1; AT3G15260.1; AT3G15260. AT3G15260.2; AT3G15260.2; AT3G15260.
GeneID	820757.
KEGG	ath:AT3G15260.
Organism-specific databases
TAIR	At3g15260.
Phylogenomic databases
eggNOG	COG0631.
HOGENOM	HOG000233896.
InParanoid	Q9LDA7.
OMA	AFHEMED.
PhylomeDB	Q9LDA7.
ProtClustDB	CLSN2915658.
Gene expression databases
Genevestigator	Q9LDA7.
Family and domain databases
Gene3D	3.60.40.10. 1 hit.
InterPro	IPR001932. PP2C-like. IPR015655. Protein_Pase_2C. [Graphical view]
PANTHER	PTHR13832. PTHR13832. 1 hit.
Pfam	PF00481. PP2C. 1 hit. [Graphical view]
SMART	SM00331. PP2C_SIG. 1 hit. SM00332. PP2Cc. 1 hit. [Graphical view]
SUPFAM	SSF81606. PP2C-related. 1 hit.
PROSITE	PS01032. PP2C. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

P2C39_ARATH

Accession

Primary (citable) accession number: Q9LDA7
Secondary accession number(s): Q8L834

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	October 1, 2000
Last modified:	May 1, 2013
This is version 72 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program