Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Vacuolating cytotoxin

Gene

vacA

Organism
Helicobacter pylori (Campylobacter pylori)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Vacuolating cytotoxinImported
Gene namesi
Name:vacAImported
OrganismiHelicobacter pylori (Campylobacter pylori)Imported
Taxonomic identifieri210 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliQ9LBC8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1055 – 1328Autotransporter (TC 1.B.12)InterPro annotationAdd BLAST274

Family and domain databases

Gene3Di2.40.128.130. 1 hit.
InterProiIPR005546. Autotransporte_beta.
IPR006315. OM_autotransptr_brl.
IPR003842. Vacuolating_cytotoxin.
[Graphical view]
PfamiPF02691. VacA. 1 hit.
[Graphical view]
PRINTSiPR01656. VACCYTOTOXIN.
SMARTiSM00869. Autotransporter. 1 hit.
[Graphical view]
SUPFAMiSSF103515. SSF103515. 1 hit.
TIGRFAMsiTIGR01414. autotrans_barl. 1 hit.
PROSITEiPS51208. AUTOTRANSPORTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9LBC8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELQQTHRKI NRPLVSLALV GLLVSITPQK SHAAFFTTVI IPAIVGGIAS
60 70 80 90 100
GAAVGTVSGL LGWGLKQAEE ANKTPDKPDK VWRIQAESFN EFPNKEYDLY
110 120 130 140 150
KSLLSSKIDG GWDWGNAARH YWVKGGQWNK LEVDMKDAVG TYKLSGLKNF
160 170 180 190 200
TGGDLNVNMQ KATLRLGQFN GNSFTSFKDS ADRTTRVDFQ NAKNISIDNF
210 220 230 240 250
LEINNRVGSG AGRKASSTVL TLQASEGITS DKNAEISLYD GATLNLASNS
260 270 280 290 300
VKLMGNVWMG RLQYVGAYLA PSYSTINTSK VVGEVNFNHL TVGDHNAAQA
310 320 330 340 350
GIIASKKTYI GTLDLWQSAG LNIIAPPEGG YKDKPNNTNS QSGAKNDKNE
360 370 380 390 400
SAKNDKQESS PNNSNTQVIN PPNSGQKTEI QPTQVIDGPF AGAQDTKVNI
410 420 430 440 450
NRINTNADGT IKVGGYTASL TTNAANLNIG KGGVNLSNQA SGRSLLVENL
460 470 480 490 500
TGNITVDGAL MVNKEAGGAA LPGSSANFEF KAGVDTKNGT ATFNNDIRLG
510 520 530 540 550
KAVNLKVDAH TINFNGNMYL GRFTHLKVNG HTANFKNIDA SKGRNGIDTT
560 570 580 590 600
ILDFSGVTNK VNINKLITAS TNVAIKNFDI KELVVTTNGL SVGKYTDFTE
610 620 630 640 650
DIGDQSPIGI VRLGKGYSPL YAGGVRFKSG KKLVIDEIYH APWNYFGTLG
660 670 680 690 700
ITDVEITKRI LFGAPGNIAG KTGLMFNNLT LNSNASMDYG KDLDLTIQGH
710 720 730 740 750
FTNNQGTMNL FVQDGRVATL NAGHQASMIF NNLVDSTTGF YKPLIKINNA
760 770 780 790 800
QNLTKNKEHV LVRARNIDYN LVGVQGASYD NIFASNTNLM EQFKERLALY
810 820 830 840 850
NNNNRMDICV VRKDNLNDIK ACGMAIGNQA MVNNPENYKY LEGKAWKNTG
860 870 880 890 900
INKTANNTTI AVNVGNNSTP TSSESNTTNL PTNATKNARF ARYALIKNAP
910 920 930 940 950
FAHYSATPNL VAINKHDFGT IESVFELANR SDDIDTLYAH SGAQGRDLLQ
960 970 980 990 1000
TLLIDSHNAG YARTMIDATS ANEITKQLNT ATDALNNIAS LEHKTSGLQT
1010 1020 1030 1040 1050
LSLSNAMILN SRLVNLSRRH TNNIDSFARR LQALKDQKFA SLESAAEVLY
1060 1070 1080 1090 1100
QFAPKYEKPT NVWANAIGGA SLNSGGNTSL YGTSAGVDAY LNEKVKAIVG
1110 1120 1130 1140 1150
GFGSYGYSSF NNQANSLNSG ANNANFGVYS RIFANRHEFD FEAQGALGSD
1160 1170 1180 1190 1200
QSSLNFKSAL LRDLNQSYNY LAYGAATRAS YGYDFAFFRN ALVLKPSVGV
1210 1220 1230 1240 1250
SYNHLGSTNF ESNSTHKTAL KNGASSQHLF NASANVEARY YYGDTSYFYM
1260 1270 1280 1290 1300
NAGVLQEFAN FGSSNAVSLN TFKVNAVRNP LNTHARVMMG GELQLAKEVF
1310 1320
LNLGFIYLHN LISNAGHFAS NLGMRYSF
Length:1,328
Mass (Da):143,702
Last modified:October 1, 2000 - v1
Checksum:i78C2298479CDCF3A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF050319 Genomic DNA. Translation: AAF26501.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF050319 Genomic DNA. Translation: AAF26501.1.

3D structure databases

ProteinModelPortaliQ9LBC8.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di2.40.128.130. 1 hit.
InterProiIPR005546. Autotransporte_beta.
IPR006315. OM_autotransptr_brl.
IPR003842. Vacuolating_cytotoxin.
[Graphical view]
PfamiPF02691. VacA. 1 hit.
[Graphical view]
PRINTSiPR01656. VACCYTOTOXIN.
SMARTiSM00869. Autotransporter. 1 hit.
[Graphical view]
SUPFAMiSSF103515. SSF103515. 1 hit.
TIGRFAMsiTIGR01414. autotrans_barl. 1 hit.
PROSITEiPS51208. AUTOTRANSPORTER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9LBC8_HELPX
AccessioniPrimary (citable) accession number: Q9LBC8
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: October 5, 2016
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.