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Protein
Submitted name:

Putative transcription regulator

Gene

cprK

Organism
Desulfitobacterium dehalogenans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulationSAAS annotation

Keywords - Ligandi

DNA-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Putative transcription regulatorImported
Gene namesi
Name:cprKImported
OrganismiDesulfitobacterium dehalogenansImported
Taxonomic identifieri36854 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesPeptococcaceaeDesulfitobacterium

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2H6CX-ray2.90A/B1-232[»]
ProteinModelPortaliQ9LAS2.
SMRiQ9LAS2. Positions 19-226.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9LAS2.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini35 – 8753Cyclic nucleotide-bindingInterPro annotationAdd
BLAST
Domaini147 – 22074HTH crp-type DNA-bindingInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains HTH crp-type DNA-binding domain.SAAS annotation
Contains cyclic nucleotide-binding domain.SAAS annotation

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
2.60.120.10. 1 hit.
InterProiIPR018490. cNMP-bd-like.
IPR000595. cNMP-bd_dom.
IPR012318. HTH_CRP.
IPR014710. RmlC-like_jellyroll.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF13545. HTH_Crp_2. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF51206. SSF51206. 1 hit.
PROSITEiPS50042. CNMP_BINDING_3. 1 hit.
PS51063. HTH_CRP_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9LAS2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAEGLDKDF CGAIIPDSFF PIEKLRNYTD MGIIREFAKG SAIIMPGEDT
60 70 80 90 100
TSMIFLMDGK IKLDIIFEDG SEKLLYYAGS NSLIGRLYPT GNNIYATAME
110 120 130 140 150
QTRTCWFSEE CLRVIFRTDE DMIFEIFKNY LTKVAYYARQ VAEINTYNPT
160 170 180 190 200
IRILRLFYEL CSSQGKRVGD TYEITMPLSQ KSIGEITGAH HVTVSKVLAC
210 220 230
LKKENILDKK KNKFIVYNLE ELKHLSEQTS YY
Length:232
Mass (Da):26,647
Last modified:October 1, 2000 - v1
Checksum:i51576C61666071E2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF115542 Genomic DNA. Translation: AAF67815.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF115542 Genomic DNA. Translation: AAF67815.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2H6CX-ray2.90A/B1-232[»]
ProteinModelPortaliQ9LAS2.
SMRiQ9LAS2. Positions 19-226.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiQ9LAS2.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
2.60.120.10. 1 hit.
InterProiIPR018490. cNMP-bd-like.
IPR000595. cNMP-bd_dom.
IPR012318. HTH_CRP.
IPR014710. RmlC-like_jellyroll.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF13545. HTH_Crp_2. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF51206. SSF51206. 1 hit.
PROSITEiPS50042. CNMP_BINDING_3. 1 hit.
PS51063. HTH_CRP_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Purification and molecular characterization of ortho-chlorophenol reductive dehalogenase, a key enzyme of halorespiration in Desulfitobacterium dehalogenans."
    van de Pas B.A., Smidt H., Hagen W.R., van der Oost J., Schraa G., Stams A.J., de Vos W.M.
    J. Biol. Chem. 274:20287-20292(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: JW/IU-DC1Imported.
  2. "Transcriptional regulation of the cpr gene cluster in ortho-chlorophenol-respiring Desulfitobacterium dehalogenans."
    Smidt H., van Leest M., van der Oost J., de Vos W.M.
    J. Bacteriol. 182:5683-5691(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: JW/IU-DC1Imported.
  3. Cited for: X-RAY CRYSTALLOGRAPHY (2.90 ANGSTROMS).

Entry informationi

Entry nameiQ9LAS2_9FIRM
AccessioniPrimary (citable) accession number: Q9LAS2
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: May 11, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.