Q9L9F2 (Q9L9F2_STRSH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
NovP EMBL AAF67509.1

Gene names

Name:

novP EMBL AAF67509.1

Organism

Streptomyces spheroides (Streptomyces caeruleus) EMBL AAF67509.1

Taxonomic identifier

195949 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptomycineae › Streptomycetaceae › Streptomyces

Protein attributes

Sequence length	262 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Technical term	3D-structure PDB 2WK1
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Region	64 – 65	2	S-adenosyl-L-homocysteine binding PDB 2WK1
	Region	92 – 96	5	S-adenosyl-L-homocysteine binding PDB 2WK1
	Region	122 – 126	5	S-adenosyl-L-homocysteine binding PDB 2WK1
	Region	196 – 197	2	S-adenosyl-L-homocysteine binding PDB 2WK1
Sites
	Binding site	178	1	S-adenosyl-L-homocysteine PDB 2WK1
	Binding site	202	1	S-adenosyl-L-homocysteine PDB 2WK1

Sequences

	Sequence		Length	Mass (Da)
	Q9L9F2 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 2FC79BADAC4E0184	FASTA	262	29,967
	10 20 30 40 50 60 MAPIVETAKE TNSDSSLYLD LMIKVLAGTV YEDPAHRENF SHRDSTYREE VRNEGRDWPA 70 80 90 100 110 120 NAHTMIGIKR LENIRQCVED VIGNNVPGDL VETGVWRGGA CILMRGILRA HDVRDRTVWV 130 140 150 160 170 180 ADSFQGIPDV GEDGYAGDRK MALHRRNSVL AVSEEEVRRN FRNYDLLDEQ VRFLPGWFKD 190 200 210 220 230 240 TLPTAPIDTL AVLRMDGDLY ESTWDTLTNL YPKVSVGGYV IVDDYMMCPP CKDAVDEYRA 250 260 KFDIADELIT IDRDGVYWQR TR

References

[1]	"Identification of the novobiocin biosynthetic gene cluster of Streptomyces spheroides NCIB 11891." Steffensky M., Muhlenweg A., Wang Z.X., Li S.M., Heide L. Antimicrob. Agents Chemother. 44:1214-1222(2000) [PubMed: 10770754] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: NCIB 11891 EMBL AAF67509.1.
[2]	Steffensky M., Muehlenweg A., Wang Z., Li S.M., Heide L. Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: NCIB 11891 EMBL AAF67509.1.
[3]	"The crystal structure of the novobiocin biosynthetic enzyme NovP: the first representative structure for the TylF O-methyltransferase superfamily." Gomez Garcia I., Stevenson C.E., Uson I., Freel Meyers C.L., Walsh C.T., Lawson D.M. J. Mol. Biol. 395:390-407(2010) [PubMed: 19857499] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.40 ANGSTROMS) IN COMPLEX WITH S-ADENOSYL-L-HOMOCYSTEINE.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AF170880 Genomic DNA. Translation: AAF67509.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2WK1	X-ray	1.40	A	1-262	[»]

ModBase

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Protocols and materials databases

StructuralBiologyKnowledgebase

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Family and domain databases

InterPro

IPR008884. TylF_MeTrfase.
[Graphical view]

Pfam

PF05711. TylF. 1 hit.
[Graphical view]

ProtoNet

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Entry information

Entry name

Q9L9F2_STRSH

Accession

Primary (citable) accession number: Q9L9F2

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2000
Last sequence update:	October 1, 2000
Last modified:	July 27, 2011
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)