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Protein

Sulfofructosephosphate aldolase

Gene

yihT

Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Cleaves 6-deoxy-6-sulfo-D-fructose 1-phosphate (SFP) to form dihydroxyacetone phosphate (DHAP) and 3-sulfolactaldehyde (SLA).UniRule annotation

Catalytic activityi

6-deoxy-6-sulfo-D-fructose 1-phosphate = glycerone phosphate + 2-hydroxy-3-oxopropane-1-sulfonate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Lyase

Names & Taxonomyi

Protein namesi
Recommended name:
Sulfofructosephosphate aldolaseUniRule annotation (EC:4.1.2.57UniRule annotation)
Short name:
SFP aldolaseUniRule annotation
Gene namesi
Name:yihT
Ordered Locus Names:STM4022
OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Taxonomic identifieri99287 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000001014 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002039721 – 292Sulfofructosephosphate aldolaseAdd BLAST292

Proteomic databases

PaxDbiQ9L7R9.
PRIDEiQ9L7R9.

Interactioni

Protein-protein interaction databases

STRINGi99287.STM4022.

Structurei

Secondary structure

1292
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi6 – 9Combined sources4
Beta strandi16 – 20Combined sources5
Helixi25 – 33Combined sources9
Helixi42 – 56Combined sources15
Helixi57 – 59Combined sources3
Beta strandi61 – 65Combined sources5
Turni67 – 70Combined sources4
Helixi71 – 76Combined sources6
Beta strandi84 – 89Combined sources6
Beta strandi91 – 96Combined sources6
Beta strandi99 – 106Combined sources8
Helixi112 – 117Combined sources6
Beta strandi122 – 129Combined sources8
Helixi135 – 150Combined sources16
Turni151 – 153Combined sources3
Beta strandi155 – 162Combined sources8
Helixi173 – 184Combined sources12
Beta strandi190 – 194Combined sources5
Helixi197 – 200Combined sources4
Helixi204 – 216Combined sources13
Beta strandi222 – 224Combined sources3
Turni231 – 233Combined sources3
Helixi234 – 243Combined sources10
Beta strandi248 – 252Combined sources5
Helixi253 – 256Combined sources4
Helixi257 – 259Combined sources3
Helixi265 – 271Combined sources7
Helixi273 – 289Combined sources17

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1TO3X-ray2.70A2-292[»]
ProteinModelPortaliQ9L7R9.
SMRiQ9L7R9.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9L7R9.

Family & Domainsi

Sequence similaritiesi

Belongs to the aldolase LacD family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D2M. Bacteria.
COG3684. LUCA.
HOGENOMiHOG000244296.
KOiK01671.
OMAiLCQIAEN.
PhylomeDBiQ9L7R9.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_01912. SFP_aldolase. 1 hit.
InterProiIPR013785. Aldolase_TIM.
IPR002915. DeoC/FbaB/lacD_aldolase.
IPR017291. SFP_aldolase_YihT.
[Graphical view]
PfamiPF01791. DeoC. 1 hit.
[Graphical view]
PIRSFiPIRSF037840. Aldolase_YihT. 1 hit.
SMARTiSM01133. DeoC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9L7R9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNNYTIKDIT RASGGFAMLA VDQREAMRLM FAAAGAKTPV ADSVLTDFKV
60 70 80 90 100
NAAKILSPYA SAVLLDQQFC YRQAVEQNAV AKSCAMIVAA DDFIPGNGIP
110 120 130 140 150
VDNVVLDKKI NAQAVKRDGA KALKLLVLWR SDEDAQQRLN MVKEFNELCH
160 170 180 190 200
SNGLLSIIEP VVRPPRCGDK FDREQAIIDA AKELGDSGAD LYKVEMPLYG
210 220 230 240 250
KGARSDLLTA SQRLNGHINM PWVILSSGVD EKLFPRAVRV AMEAGASGFL
260 270 280 290
AGRAVWSSVI GLPDTELMLR DVSAPKLQRL GEIVDEMMAK RR
Length:292
Mass (Da):31,866
Last modified:January 23, 2002 - v2
Checksum:iB4BC0AC12D7197E1
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti235P → L in AAF27922 (Ref. 1) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF220438 Genomic DNA. Translation: AAF27922.1.
AE006468 Genomic DNA. Translation: AAL22861.1.
RefSeqiNP_462902.1. NC_003197.1.
WP_001067421.1. NC_003197.1.

Genome annotation databases

EnsemblBacteriaiAAL22861; AAL22861; STM4022.
GeneIDi1255548.
KEGGistm:STM4022.
PATRICi32386914. VBISalEnt20916_4237.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF220438 Genomic DNA. Translation: AAF27922.1.
AE006468 Genomic DNA. Translation: AAL22861.1.
RefSeqiNP_462902.1. NC_003197.1.
WP_001067421.1. NC_003197.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1TO3X-ray2.70A2-292[»]
ProteinModelPortaliQ9L7R9.
SMRiQ9L7R9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi99287.STM4022.

Proteomic databases

PaxDbiQ9L7R9.
PRIDEiQ9L7R9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL22861; AAL22861; STM4022.
GeneIDi1255548.
KEGGistm:STM4022.
PATRICi32386914. VBISalEnt20916_4237.

Phylogenomic databases

eggNOGiENOG4105D2M. Bacteria.
COG3684. LUCA.
HOGENOMiHOG000244296.
KOiK01671.
OMAiLCQIAEN.
PhylomeDBiQ9L7R9.

Miscellaneous databases

EvolutionaryTraceiQ9L7R9.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_01912. SFP_aldolase. 1 hit.
InterProiIPR013785. Aldolase_TIM.
IPR002915. DeoC/FbaB/lacD_aldolase.
IPR017291. SFP_aldolase_YihT.
[Graphical view]
PfamiPF01791. DeoC. 1 hit.
[Graphical view]
PIRSFiPIRSF037840. Aldolase_YihT. 1 hit.
SMARTiSM01133. DeoC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSQUT_SALTY
AccessioniPrimary (citable) accession number: Q9L7R9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 26, 2001
Last sequence update: January 23, 2002
Last modified: November 2, 2016
This is version 90 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.