Q9L4W3 (Q9L4W3_9ACTO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
NysC EMBL AAF71776.1

Gene names

Name:

nysC EMBL AAF71776.1

Organism

Streptomyces noursei EMBL AAF71776.1

Taxonomic identifier

1971 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptomycineae › Streptomycetaceae › Streptomyces

Protein attributes

Sequence length	11096 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Ligand	Phosphopantetheine RuleBase RU000721
Molecular function	Transferase RuleBase RU000693
Gene Ontology (GO)
Biological process	biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	acyl carrier activity Inferred from electronic annotation. Source: InterPro cofactor binding Inferred from electronic annotation. Source: InterPro nucleotide binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity Inferred from electronic annotation. Source: InterPro phosphopantetheine binding Inferred from electronic annotation. Source: InterPro transferase activity, transferring acyl groups other than amino-acyl groups Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9L4W3 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 776CAEAFCAE551DD	FASTA	11,096	1,150,432
	10 20 30 40 50 60 MSTNPDKYVE ALRSSLKEIE RLRRQNEQLV AAAVEPVAVV GIGCRFPGGV TSPEDLWELV 70 80 90 100 110 120 AEGRDVIGPF PQDRGWDLEK LAGGGEGGSL AQVGGFVEDA AGFDPGFFGI SPREAVAMDP 130 140 150 160 170 180 QQRILLEITW EALERAGIDP STLRGTPTGV FVGTTGQDYG EVIKASAEDV EVYSTTGHAA 190 200 210 220 230 240 SVISGRLSYT LGAEGPAVTV DTGCSSSLVA LHWAVQALRG GECSMALAGG ASIMATPGPF 250 260 270 280 290 300 VAFTAQSGLA ADGRCKPFSD RADGTGWGEG AGMLVLMRLS DAQREGRPVL AVLRGSAINQ 310 320 330 340 350 360 DGASNGLTAP NGPSQQRVIR AALDSAHLTA ADIDAVEAHG TGTTLGDPIE AQALLATYGQ 370 380 390 400 410 420 DRPRPLWLGS VKSNIGHTQA ASGAAGVIKM IMALQRGVLP RSLHATEPTT DVDWTAGSVD 430 440 450 460 470 480 LLDETVAWPE TGRARRAGVS SFGISGTNAH VILEQAPTAP EEPTTEPTVR PAVVPWALSA 490 500 510 520 530 540 RTAAALDAQR ARLTGHLADT PDADPLDVGY ALADGRATFE HRAVLLPDGT ELAHGTAGEG 550 560 570 580 590 600 PCAVLFSGQG SQRPGMGREL HARFPVFAAA FDEITALLDT HLDRPLREVV WGTDADLLND 610 620 630 640 650 660 TGWAQPALFA VEVALYRLVA SLGVTPDFVG GHSIGELAAA HVAGVLSLED ACTLVAARAR 670 680 690 700 710 720 LMQALPRGGA MLAIRATEDE VTPHLTDDVS IAAVNGPTSV VVAGTEEAVA AIGARFTAQD 730 740 750 760 770 780 RKTTRLRVSH AFHSPLMDPM LAEFRAVAAG LTYHEPRIPV LSNLTGTVAA VADLCSADYW 790 800 810 820 830 840 VRHVREAVRF ADGVTALTDR GVTTLVELGP DGVLSAMAQE SLPDGAAAVP LLRKDRPEEL 850 860 870 880 890 900 SAVTGLARAH VRGVTVRWAG LFDGTGARRA DLPTYPFQHQ RFWPTAARAA QDVTAAGLGA 910 920 930 940 950 960 ADHPLLGATV ELADGAGYLF TSRLSVRTHP WLADHGVQGR ALLPGTAFVE LAVRAGDEAG 970 980 990 1000 1010 1020 CDRVEELTLA APLVLPERGG VQLQVRVGAP DAAGRRTLGI FSRVEDGFDL PWSQHATGVL 1030 1040 1050 1060 1070 1080 TAGAGAPDPT FDATVWPPSG AEPVDLTGAY ERLAALGFQY GPAFQGLRAA WRRDTEVYAE 1090 1100 1110 1120 1130 1140 VALPDGADTD PAAFGLHPAL LDAAQHAAAY ADLGAISRGG LPFAWEGVSL AAAGATTVRA 1150 1160 1170 1180 1190 1200 RIAPAGEDTV TIAVYDAAGG TVLSVDSLVS REVPADAPGA AGTVHRDSLF HVEWTPLQGR 1210 1220 1230 1240 1250 1260 PGPAPATVAV LGPDPDALAD TLRATGIRTT APRDLAALAD AEGPVPDLVV TTLTTTPGAP 1270 1280 1290 1300 1310 1320 VPDAAHATTA AVLALAQQWL ADDRFADARL VLVTRGATDG TDPAAAAAGG LIRTARTENP 1330 1340 1350 1360 1370 1380 GRFALLDLAP DTGRPDPETL ATALAASHDE PDLAVRGTDV HAARLARVPL ATEPTTWNPD 1390 1400 1410 1420 1430 1440 GTVLITGGTG GLGAVLARHL VATHGVRHLL LASRRGPAAD GADDLTAELT GLGATVHIAA 1450 1460 1470 1480 1490 1500 CDVADPAALA DLLGTVPAGH PLTVVVHTAG VVDDGVLGSL TPQRLDTVLR PKADAAWHLH 1510 1520 1530 1540 1550 1560 EATRHLDLDA FVLFSSVAAT LGSPGQANYA AGNAFLDALA ARRAATGLPA TSLAWGPWTQ 1570 1580 1590 1600 1610 1620 SVGMTSSLSD LDVERIARSG MPPLTLEQGT ALFDAALAAG PAALAPVRLD LPVLRTQGDI 1630 1640 1650 1660 1670 1680 APLLRGLIRT PVRRTAAQVS QTADGLAQRL AGLDAAARRE ALLELVRTQI AQVLGHADAT 1690 1700 1710 1720 1730 1740 EVETGRQFQD LGFDSLTAVE LRNALNTATG LRLPATMVFD YPTPHALADH LRDELLGTEA 1750 1760 1770 1780 1790 1800 ESTTAVPVPT RTAGTDDPIV IVGMACRYPG GIASPEDLWR LVSQGADATG PFPTNRGWDL 1810 1820 1830 1840 1850 1860 DNLYDPDPDR PGRTHVRAGG FLHDAGSFDA DFFGMSPREA MATDSQQRLL LELSWEAVER 1870 1880 1890 1900 1910 1920 AGIDPASLRD SGTGVFAGVM YNDYGTTLTG DEYEAFRGNG SAPSVASGRV SYTLGLEGPA 1930 1940 1950 1960 1970 1980 VTVDTACSSS LVALHWAAQA LRAGECSLAL AGGVTVMSTP STFVEFSRQR GLAPDGRSKA 1990 2000 2010 2020 2030 2040 FAEAADGVAW SEGVGMLVLE RQSDAVRNGH EILAVVRGSA VNQDGASNGL TAPNGPSQQR 2050 2060 2070 2080 2090 2100 VIRQALASGG LSTADVDAVE AHGTGTTLGD PIEAQALLAT YGRDRDPENP LLLGSIKSNI 2110 2120 2130 2140 2150 2160 GHTQAAAGVA GVIKMVMAMR HGVLPQTLHV DAPSSHVDWS VGAVELLTEQ TAWPETGRAR 2170 2180 2190 2200 2210 2220 RAGVSSFGIS GTNAHVVIEQ SPTAVPATPA SADRSVEEPP AVPWALSGKT PDALRDQAAR 2230 2240 2250 2260 2270 2280 LLAHVEAHPA LRPVDISYSL IATRTAFDHR AVVLGTDRAE ALRALTALAA GETDPAALTG 2290 2300 2310 2320 2330 2340 TVRTGRTAFL FSGQGSQRLG MGRVLYERFP AFAEALDTVL TALDAELGHP LRDIIWGEDA 2350 2360 2370 2380 2390 2400 QLVDRTGYTQ PALFAIEVAL FRLLEAWGIT PDFVAGHSIG EIAAAHVAGV LSLGDACRLV 2410 2420 2430 2440 2450 2460 VARAVLMQSL PEGGAMIAVQ ATEDEVLPLL TDDVSIAAVN SPTSVVVSGY ENATLAVARH 2470 2480 2490 2500 2510 2520 FADQGRRTTR LRVSHAFHSP LMAPMLDDFR AVVESLTFTA PTTPVVSNLT GELAPAEALC 2530 2540 2550 2560 2570 2580 SADYWVRHVR EAVRFADGIR TLADRGVTTF VELGPDSVLS AMAQESAPEG AGTIPLLRRD 2590 2600 2610 2620 2630 2640 RPEEQAVLAA LCHLQVLGVE ADWSATFRGL DPVRVDLPTY AFQHRWFWPA ARPARPDDVR 2650 2660 2670 2680 2690 2700 AAGLGAAEHP LLGAAVQLPD DDGALFTGRL SLRTHPWLAD HTVLGTVLLP GTALVELAVR 2710 2720 2730 2740 2750 2760 AGDETGSGHL EELTLAAPLT LPEDGATLLQ VRVGSADDTG RRTVTVHARP DDTADRTWTL 2770 2780 2790 2800 2810 2820 HATGVLATTP PAAAAFDTTV WPPADAEPLT TDDCYAHFTT HRFAYGPAFQ GLRAAWRAGD 2830 2840 2850 2860 2870 2880 VLYAEVALPE SATDEAAAFG LHPALLDAGL HAALLADDRD TGLPFSWEGV TLHASGATAL 2890 2900 2910 2920 2930 2940 RVRLAPNGPN GLSVTAADPA GNPVATVTRL LARPLDAEQL TIHSALTRDA LFHLDWTPVP 2950 2960 2970 2980 2990 3000 LPDTANSAPP ALLGPDTAVL ADALGDPAVA RHATLDDLLA GDTTPPATVL VPLGAPLDGD 3010 3020 3030 3040 3050 3060 TAQHAHALTR SALTLVQQWL ATDRLADSRL VFVTHGAVAT DDAPPTDLAA AAVWGLIRSA 3070 3080 3090 3100 3110 3120 QTENPGTFTL LDLDTEPDST TALSRALTLD EPQLLLRAGR ARAARLTRTP APTTTTHTPW 3130 3140 3150 3160 3170 3180 SADGTVLVTG GTGGLGGLVA RHLVRSCGVR HLLLTSRSGV GAAGAAGLVA ELESLGARVV 3190 3200 3210 3220 3230 3240 VAACDVGDGS AVAELVAGVS ESYPLSAVVH AAGVLDDGVV GSLTPERLAA VLRPKVDGAW 3250 3260 3270 3280 3290 3300 NLHEATRGLD LDAFVVFSSV AGVFGGAGQA NYAAGNAFLD ALMVHRVAGG LPGVSLAWGA 3310 3320 3330 3340 3350 3360 WDQGVGMTAG LTERDVRRAA ESGMPLLTVD QGVALFDAAL ATGSAALVPV RLDLAALRTR 3370 3380 3390 3400 3410 3420 GDIAPLLRGL VRAPLRRTAA TGLATGADTG LVQRLGRLDH AQRHEALLDM VRSSAALVLG 3430 3440 3450 3460 3470 3480 HADGNAIDAE RAFRDLGFDS LTAVELRNRL RTATGLHLSA TMVFDHPTLS ALAEHLRDEL 3490 3500 3510 3520 3530 3540 FGAVESEVRV PVQALPPTAD DPIVVVGMAC RFPGGVTSPE DLWRLVDDGT DAITTFPTNR 3550 3560 3570 3580 3590 3600 GWDLDNLYDP DPEHFGTSYT RSGGFLHEAG EFDPAFFGMS PREALATDSQ QRLLLESSWE 3610 3620 3630 3640 3650 3660 AIERAGIDPL TLRGSATGVF AGVMYSDYGS ILGGKEFEGF QGQGSAGSVA SGRVSYALGF 3670 3680 3690 3700 3710 3720 EGPAVTVDTA CSSSLVALHW AAQALRAGEC SLALAGGVTV MSTPSTFVEF SRQRGLAPDG 3730 3740 3750 3760 3770 3780 RSKAFAEAAD GVGWSEGVGI LVLERQSDAV RNGHEILAVI RGSAVNQDGA SNGLTAPNGP 3790 3800 3810 3820 3830 3840 SQQRVIRQAL ASGGLSTADV DAVEAHGTGT TLGDPIEAQA LLATYGRDRD PENPLWLGSL 3850 3860 3870 3880 3890 3900 KSNIGHTQAA AGVAGVIKMV MAMRHGVLPQ TLHVDAPSSH VDWSVGAVEL LTEQTAWPET 3910 3920 3930 3940 3950 3960 GRVRRAGVSS FGISGTNAHV IVEQPALVES PAAEPSGREP GVVPLPLSGK SPEALRDQAA 3970 3980 3990 4000 4010 4020 RLLAGLAERP ALRPLDLGYS LATTRSAFDH RAVVLATDRA DAVRALTALA AADADLSAVV 4030 4040 4050 4060 4070 4080 GDTRTGRHAV LFSGQGSQRL GMGRELYERF PVFAEALDVA IDHLDAALPA QASLREVMWG 4090 4100 4110 4120 4130 4140 DDVELLDETG WTQPALFAVE VALFRLVESW GVRPDFVAGH SIGEIAAAHV VGVFSLEDAC 4150 4160 4170 4180 4190 4200 RLVAARATLM QALPTGGAMI AIQAAEDEVT QHLTDDVSIA AVNGPTSVVV SGAESAARTV 4210 4220 4230 4240 4250 4260 ADRLAENGRK TTRLRVSHAF HSPLMDPMLA EFRAVAEGLS YATPTLPVVS NLTGRLATAD 4270 4280 4290 4300 4310 4320 DLCSAEYWAR HVREAVRFAD GVSTLENEGV TTFLELGPDG VLSAMAQQSL TGDAATVPAL 4330 4340 4350 4360 4370 4380 RKDRDEETSA LTALAHLHTA GLRVDWAAFF AGSGATRVDL PTYAFQHATY WPTGTLPTAH 4390 4400 4410 4420 4430 4440 AAAVGLTAAE HPLLNGSVEL AEGEGVLFTG RLSLQSHPWL ADHAVMGQVL LPGTALLELA 4450 4460 4470 4480 4490 4500 FRAGDEAGCD RVEELTLAAP LVLPERGAVQ TQVRVGVADD TGRRTVTVHS RPEHATDVSW 4510 4520 4530 4540 4550 4560 TQHATGTLTM GSAPADTGFD ATAWPPADAE PLATDDCYAR FTTLGFAYGP VFQGLRAAWR 4570 4580 4590 4600 4610 4620 AGDVLYAEVA LAESTGDEAT AFGLHPALLD AALHASLVAH EGEESNGGLP FSWEGATLYA 4630 4640 4650 4660 4670 4680 TGATALRVRL TPTGTDGRSV AIAVADTAGR PVAAIDNLVS RRVSGDQLTG AAGLARDALF 4690 4700 4710 4720 4730 4740 TLDWNPVPEN LVPENPVPEN TGGGHAQDQD GRPAAATVAL VGADGTAIAA DLTAAGIHTT 4750 4760 4770 4780 4790 4800 LHPDLTTLAT TDADVPKTVL IPLTGTGTGT GTGTESTDGI GTGAAESDAS APSPAEVAHT 4810 4820 4830 4840 4850 4860 LSTAALALVQ EWTAQERFAG SRLAFVTTGA TAAGGTDVMD VAAAAVWGLV RSAQSEAPDT 4870 4880 4890 4900 4910 4920 FVLIDRDPGP AGTHDRTAAA ERGQLLLRAL HTDEPQLALR DGGVLAARLA RFDTAAALTP 4930 4940 4950 4960 4970 4980 PADRAWRLDS TAKGSLNGLA LTPYPAALAP LTGHEVRVEV RAAGLNFRDV LNALGMYPGD 4990 5000 5010 5020 5030 5040 DVGSFGSEAA GVVVEVGPEV TGLAPGDQVM GMITGSFGSL AVDDARRLAR LPEDWSWETG 5050 5060 5070 5080 5090 5100 ASVPLVFLTA YYALKELGGL RAGEKVLVHA GAGGVGMAAI QIARHVGAEV FATASEGKWD 5110 5120 5130 5140 5150 5160 VLRSLGVADD HIASSRTLDF EAAFAEVAGD RGLDVVLNSL AGDFVDASMR LLGDGGRFLE 5170 5180 5190 5200 5210 5220 MGKTDIRAAD SVPDGLSYQS FDLAWVVPET IGTMLAELMD LFRTGALRPL PVRTWDVRHA 5230 5240 5250 5260 5270 5280 KDAFRFMSMA KHIGKIVLTL PRSWKPEGTV LVTGGTGGLG GLVARHLVRS CGVRHLLLTS 5290 5300 5310 5320 5330 5340 RSGVGAAGAA GLVAELESLG ARVVVAACDV GDGSAVAELV AGVSESYPLS AVVHAAGVLD 5350 5360 5370 5380 5390 5400 DGVVGSLTPE RLAAVLRPKV DGAWNLHEAT RGLDLDAFVV FSSVAGVFGG AGQANYAAGN 5410 5420 5430 5440 5450 5460 AFLDALMVHR VAGGLPGVSL AWGAWDQGVG MTAGLTERDV RRAAESGMPL LTVDQGVALF 5470 5480 5490 5500 5510 5520 DAALATGSAA LVPVRLDLAA LRTRGDIAPL LRGLVKAPIR RAAATTPGDT GLAEQLTRLQ 5530 5540 5550 5560 5570 5580 RAERRDTLLA LVRDQAAMVL GHTSGDGVDP SRAFRDLGFD SLTAVELRNR IGAATGLRLP 5590 5600 5610 5620 5630 5640 ATAVFDYPTA DALAAHLLTE LLGPDAESDP DEPGDPTAGP TDDPIVIIGM SCRFPGDIGS 5650 5660 5670 5680 5690 5700 PEDLWRLLGD GADVVTDFPT NRGWDLDNLY DPDPAHAGTS YARTGGFLHD AADFDADFFG 5710 5720 5730 5740 5750 5760 MSPREAMATD SQQRLLLESS WEAIERAGID PLTLRDSRTG VFAGVMYSGY GTRLDGAEFE 5770 5780 5790 5800 5810 5820 GFQGQGSALS VASGRVSYTF GFEGPAMTVD TACSSSLVAL HLAAQALRGG ECTLALAGGV 5830 5840 5850 5860 5870 5880 TVMSIPDTFI EFSRQRGLAP DGRSKPFSES ADGVGWSEGV GMLLLERQSD AVRNGHQILA 5890 5900 5910 5920 5930 5940 VVRGSAVNQD GASNGLTAPN GPSQQRVIRQ ALASGGLSTA DVDAVEAHGT GTTLGDPIEA 5950 5960 5970 5980 5990 6000 QALLATYGRD RDPENPLLLG SIKSNLGHTQ AAAGVAGVIK MVMAMRHGVL PRSLNITEPS 6010 6020 6030 6040 6050 6060 SHVDWSAGAV ELLTEQTAWP ETGRARRAGI SSFGISGTNA HVILEQPEAA RHSAPEEADT 6070 6080 6090 6100 6110 6120 AEAAAKAPAT AHLPVMPWAL SGKTPEALRA QAARLLAHLQ QRPELAPADI ALSLATQRSQ 6130 6140 6150 6160 6170 6180 FTHRAVVLST DRDEATRALS ALATTAASDP SALTGTVTMG RCAVLFSGQG SQRLGMGREL 6190 6200 6210 6220 6230 6240 YERFPVFAEA LDVVIDHLDA ALPAQAGLRE VMWGDDVELL NETGWTQPAL FAIEVALFRL 6250 6260 6270 6280 6290 6300 VESWGVRPDF VAGHSIGEIA AAHVVGVFSL EDACRLVAAR ATLMQALPAG GAMIAVQATE 6310 6320 6330 6340 6350 6360 DEVIPHLTDE VAIAAVNGPT SVVISGAEEA TQTVAQHFAD QGRRTTALRV SHAFHSPLMM 6370 6380 6390 6400 6410 6420 LAEFRAVAEG LSYATPTLPV VSNLTGQVAT ADELCSAEYW VRHVREAVRF ADGVTALEAE 6430 6440 6450 6460 6470 6480 GVRTFLELGP DGVLAAMARE TVADDTVTVP VLRRNMPEER TLLTALGRLH TTGTPIDWAA 6490 6500 6510 6520 6530 6540 LLAPTGARPV DLPTYAFQHR PFWPSGPRDT ADAAAVGIAG ASHPLLNGIV ELADEEGLLF 6550 6560 6570 6580 6590 6600 TGRLSLQSHP WLADHAVMGQ VLLPGTALLE LALRAGDEVG CDHVEELTLA APLVLPERGA 6610 6620 6630 6640 6650 6660 VQTQVRVGVA DTTGRRTVTI HSRPARATTT DSDTHTGTDT PWTQHATGVL VAGLPATATV 6670 6680 6690 6700 6710 6720 PFDATVWPPA HAEPVDLADF YASRAGEGFG YGPAFQGLRA AWRRDGEVFA DVALPEAGRT 6730 6740 6750 6760 6770 6780 EAEAYGLHPA LLDAGLHAAW LVAPDGEPTR TGSVPFSWRG VFLAASGASS VRVRLGRDSD 6790 6800 6810 6820 6830 6840 GTLSLAIADT TGAPVASVQA LSMRTVSVTA LSATAGLARD ALFRLDWASA PEPACQPDDT 6850 6860 6870 6880 6890 6900 VTVIPAVAVV GTETSELTSE LTAALRAAGA DVDVRTTLST DEPAPALIAL PLVASDQTGT 6910 6920 6930 6940 6950 6960 AEAAPVPAAV HDLTRRALAL VQTRLQEQHF ADTKFVFVTR GATVGRDVAA AAVWGLVRSA 6970 6980 6990 7000 7010 7020 QSENPGCFAL VDLDPDGAVG AAALVAALVS GEPQLAVRGD VLRVARLVRR PLTEVGAGAD 7030 7040 7050 7060 7070 7080 GTGDGVGGGS GVSFSGEGAV LVTGGTGGLG AVLARHLVAE YGVRDLLLVS RSGERAVGAG 7090 7100 7110 7120 7130 7140 ELVAELAGVG ARVRVVACDV TDRAAVVELV GGHAVSAVVH AAGVLDDGMV GALTGERLSA 7150 7160 7170 7180 7190 7200 VLRPKVDAVW HLHEATRGLD LDAFVVFSSL AGVFGSPGQA NYAAANAFLD ALMTRRRAEG 7210 7220 7230 7240 7250 7260 LPGLSLAWGP WSLTDGTSGM LADAEADRLT RSGVPPLTAE QGLALFDAAL ATGDATCVPV 7270 7280 7290 7300 7310 7320 RLDLSALRAQ GEVPPLLRSL IRGRSRRAAA AESATATGLR ERLVGLNPVE RQEVLLDLVR 7330 7340 7350 7360 7370 7380 GQVALVLGHA DADDVHPARA FRELGFDSLT SVELRNRLNT VTGLRLPATM VFDYPTVEVL 7390 7400 7410 7420 7430 7440 VSYVLDELLG TDAEVATVQP AAVAVADDPI VIVGMACRYP GGVASPDDLW RLVTDGVDAV 7450 7460 7470 7480 7490 7500 SPFPTNRGWD VESLYHPDPD HLGTSYTRSG GFLHEAGEFD PGFFGMSPRE ALATDSQQRL 7510 7520 7530 7540 7550 7560 LLESSWEAIE RAGIDPVSLR GSRTGVFAGV MYSDYSAMLA SPEFEGFQGS GSSPSLASGR 7570 7580 7590 7600 7610 7620 VAYTLGLEGP AVTVDTACSS SLVAMHWAMQ ALRSGECGLA LAGGVTVMST PAVFVDFARQ 7630 7640 7650 7660 7670 7680 RGLSPDGRCK AFADAADGVG WSEGVGVLVL ERQSDAVRNG HEILAVVRGS AVNQDGASNG 7690 7700 7710 7720 7730 7740 LTAPNGPSQQ RVIRQALASG GLTAGDVDVV EAHGTGTTLG DPIEAQALLA TYGRDREPER 7750 7760 7770 7780 7790 7800 PLLLGSVKSN LGHTQAAAGV AGVIKMVLAM RHGVVPRTLH VDAPSSHVDW SEGAVELLSE 7810 7820 7830 7840 7850 7860 QAAWPETGRV RRAGVSSFGI SGTNAHVILE RPEAARRPVM ETNTVEPSTV PWVLSGKTPE 7870 7880 7890 7900 7910 7920 ALRAQAAKLL SSIEERPELR LVDVGMSLVT GRSTFEHRAV VLAADRADAA RALSAIAADE 7930 7940 7950 7960 7970 7980 ADAAAATGRV GAGRHAVLFS GQGAQRLGMG RELYERFPVF AEALDVVVDH LDAALPAQAG 7990 8000 8010 8020 8030 8040 LREVMWGDDA ELLNETGWTQ PALFAIEVAL FRLVESWGVR PDFVAGHSIG EIAAAHVAGV 8050 8060 8070 8080 8090 8100 FSLEDACRLV AARATLMQAL PAGGAMIAVQ ATEDEVTPHL TDDVAIAAIN GPNALVVSGV 8110 8120 8130 8140 8150 8160 EDAAVEIGAR FAAEGRRTTR LHVSHAFHSP LMDPMLAEFR VVAEGLSYAA PSLPVVSNLT 8170 8180 8190 8200 8210 8220 GQVATADELC SAEYWVRHVR EAVRFADGVT ALEAEGVRTF LELGPDGVLA AMAGASLTES 8230 8240 8250 8260 8270 8280 SLAVPLLRKD RPEEPAALAA LAQLHIAGAR VDWPVLFAGV GAGRVELPTY AFQRGWFWPV 8290 8300 8310 8320 8330 8340 GRVGVGGDVG AVGLGSAGHP LLGAAVELAA GAGVVLTGRL SLSSHGWLAD HAVMGRVFVP 8350 8360 8370 8380 8390 8400 GTALLEMVMR AGDEVGCGRV EELTLAAPLV LPERGGVRVQ VAVDAPDAAG RRGVGVYSCP 8410 8420 8430 8440 8450 8460 DGVGQAVWSQ HAVGVLASGV ADQVGGFGDG GVWPPQGAVS VDAEGCYELF ADAGFGYGPV 8470 8480 8490 8500 8510 8520 FQGLRAVWRR GEELFAEVAL SDEVAESADT ATGFGLHPAL LDASLHASLL SSLEGQSADG 8530 8540 8550 8560 8570 8580 GPALPFAWEG VSLFASGATA LRVRLAPAGE HAVSVTAVDP TGAPVISIDA LRTRRLTLDE 8590 8600 8610 8620 8630 8640 VNASHTQLSD ALFGVQWTTV PSTPAADHPS VAIIGTDHLG LAEALSSSSA GATTTTTAAA 8650 8660 8670 8680 8690 8700 YESLDALIAA GPEVSVPDVT LIGLTTEDAI AQYVNDHDAT VAGQGTIGAG AAAVDAARRL 8710 8720 8730 8740 8750 8760 TAEALRTIQA WLADERLAAR RLVFVTRGAA DGQDVAAAAV QGLVRSAQTE NPGTFGLLDL 8770 8780 8790 8800 8810 8820 DGTEASTAVL GEALTSDEPQ LLLRDGHLHA ARLTRLASPA DTAVPTEWNA DGTVLITGGT 8830 8840 8850 8860 8870 8880 GGLGAQFARH LVDRYGVRNL LLVSRRGPDA PGTTELVAEL TAHGAEVAVQ ACDVADGDAV 8890 8900 8910 8920 8930 8940 AALVAGVPDE HPLRAVVHTA GVLDDGVIGS LTEERLATVL RPKADAAWHL HEATRGLDLD 8950 8960 8970 8980 8990 9000 AFVVFSSVAG VFGGAGQANY AAANAFLDAL MAQRRAAGLP GLSLAWGPWD QTGGMTGMLS 9010 9020 9030 9040 9050 9060 DAEADRLARS GIPPLSAEQG LALFDAALAL AGTSTPDRAA GSAAASTSGT GDTIAIPAAA 9070 9080 9090 9100 9110 9120 LVAPVRLDLA ALAAQGEVPA ILRGLVRTRT RRTAAGGSVT VAGLVNRLSG LTADERRQEL 9130 9140 9150 9160 9170 9180 LELVRTQAAL VLGHADPASV DSTAQFRDLG FDSLTAVELR NRLSTATGLR LTATLVFDYP 9190 9200 9210 9220 9230 9240 NTDALAEHLR DELFGAVESE VRVPVQALPP TADDPIVVVG MACRFPGGVT SPEDLWRLVD 9250 9260 9270 9280 9290 9300 AGTDAITTFP TNRGWDLESL YDPDPAHLGT SYTRSGGFLH EAGEFDPAFF GMSPREALAT 9310 9320 9330 9340 9350 9360 DSQQRLLLES SWEAIERAGI DPLTLRGSAT GVFAGVMYSD YGSILGGKEF EGFQGQGSAG 9370 9380 9390 9400 9410 9420 SVASGRVSYT LGFEGPAVTV DTACSSSLVA LHLAAQALRA GECTLALAGG VTVMSTPGTF 9430 9440 9450 9460 9470 9480 VEFSRQRGLA PDGRSKAFAE AADGVGWSEG VGILVLERQS DAVRNGHEIL AVIRGSAVNQ 9490 9500 9510 9520 9530 9540 DGASNGLTAP NGPSQQRVIR QALASGGLST ADVDAVEAHG TGTTLGDPIE AQALLATYGR 9550 9560 9570 9580 9590 9600 DRDPENPLLL GSIKSNLGHT QAAAGVAGVI KMVMAMRHGV LPQTLHVDAP SSHVDWSVGA 9610 9620 9630 9640 9650 9660 VELLTEQTVW PETGRVRRAG VSSFGISGTN AHVILEQPEA VQRLAPGAAE TVEPVAIKPS 9670 9680 9690 9700 9710 9720 AEPSLVPWAL SGKSPEALRA QAARLRDFLA ERPEPRSIDI GHSLAVTRSQ FDHRAIVLVD 9730 9740 9750 9760 9770 9780 DAKAPADSLA ALAALASGVA DPAVVSDAVS TGGSAVLFTG QGAQRLGMGR ELYGRFPVFA 9790 9800 9810 9820 9830 9840 EALDVVVDHL DAALPAQAGL REVMWGDDVE LLNETGWTQP ALFAVEVALF RLVERWGVRP 9850 9860 9870 9880 9890 9900 DFVAGHSIGE IAAAHVAGVF SLEDACRLVA ARATLMQALP TGGAMIAVQA TEDEVTPHLT 9910 9920 9930 9940 9950 9960 DEVAIAAVNG PTSVVISGAE EATQTVAQHF ADQGRRTTAL RVSHAFHSPL MDPMLAEFRA 9970 9980 9990 10000 10010 10020 VAEGLSYATP SLPVVSNLTG WLATADELCS AEYWVRHVRE AVRFADGITT LEAEGVRTFL 10030 10040 10050 10060 10070 10080 ELGPDGILSA LAQQSLAGEA VTVPVLRKDR GEESTALTAR AHLHTRGLIE DWQDFFAGVG 10090 10100 10110 10120 10130 10140 AGRVELPTYA FQRGWFWPVG RVGVGGDVGA VGLGSAGHPL LGAAVELAAG AGVVLTGRLS 10150 10160 10170 10180 10190 10200 LSSHGWLADH AVMGRVFAPG TALLEMVMRA GDEVGCGRVE ELTLAAPLVL PERGGVRVQV 10210 10220 10230 10240 10250 10260 AVDAPDAAGR RGVGVYSCPD GVGQAVWSQH AVGVLASGAA DQVGGFGDGG VWPPQGAVSV 10270 10280 10290 10300 10310 10320 DAEGCYELFA DAGFGYGPVF QGLRAVWRRG EELFAEVALS DEVAESADTA TGFGLHPALL 10330 10340 10350 10360 10370 10380 DASLHASLLS SLEGQSADGG PALPFAWEGV SLFASGATAL RVRLAPAGEH AVSVTAVDPT 10390 10400 10410 10420 10430 10440 GAPVISIDAL RTRRLTLDEV NASHTQLSDA LFGVQWTTVP STPAADHPSV AIIGTDPFGL 10450 10460 10470 10480 10490 10500 ADGLSDALPL VEERGDLAAL AASEHPVPDL VLVPVAGTRR TGVPADAEGH TDAGTSDMLR 10510 10520 10530 10540 10550 10560 SVREATAQVL EQIQQWLADD RFEAARLVFV TRGAVSVGEG GIADLAASAV WGLVRSAQSE 10570 10580 10590 10600 10610 10620 NPGCFGLLDL DLDLALDSDL APEVDIERDR DRDPVGGTVQ PALAAALHAT ADEPQLALRG 10630 10640 10650 10660 10670 10680 GTVQAARLTR IPAPQTDRAE TDPAETDRPE IDTRRPGTVL ITGGTGGLGG LLARHLVAER 10690 10700 10710 10720 10730 10740 GVRSLVLASR SGLAAEGAEK LVADLEALGA VVAVQTCDVA DGDAVAALVA GVSDEYPLTA 10750 10760 10770 10780 10790 10800 VVHTAGVLDD GVIGSLTEER LATVLRPKAD AAWHLHEATR DLDLDAFVVF SSLAGVLGGA 10810 10820 10830 10840 10850 10860 GQANYAAANT FLDALMAQRR AAGLPGVSLA WGPWDRAGGM TGTLSDAEAD RLARSGVPPI 10870 10880 10890 10900 10910 10920 SAEQGLALYD AATAGERPLV VPVRLDLAAL RGLGDVPALL RGLVRTPARR TAAAGAAPSA 10930 10940 10950 10960 10970 10980 DVLTRQLAGL GGAEQEEVLL RLVRGQAAVV LGHADGSAIG AGRQFQELGF DSLTAVEFRN 10990 11000 11010 11020 11030 11040 RLNAATGLRL PATLLFDYPT PADVVGHLRG RLGTGEVSGA GSVLAALDNL EAVIAGLSLD 11050 11060 11070 11080 11090 DAGEHQLVAG RLEVLRAKWA DMRSAEGAVD GGADVDIEEA SDDDMFALLD DELGLN

References

[1]	"Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway." Brautaset T., Sekurova O.N., Sletta H., Ellingsen T.E., StrLm A.R., Valla S., Zotchev S.B. Chem. Biol. 7:395-403(2000) [PubMed: 10873841] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: ATCC 11455 EMBL AAF71776.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF263912 Genomic DNA. Translation: AAF71776.1.
3D structure databases
HSSP	HSSP built from PDB template 1PQW based on UniProtKB P96202.
ProteinModelPortal	Q9L4W3.
SMR	Q9L4W3. Positions 1645-1735, 5244-5425.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR001227. Ac_transferase_dom. IPR009081. Acyl_carrier_prot-like. IPR014043. Acyl_transferase. IPR016035. Acyl_Trfase/lysoPLipase. IPR013149. ADH_C. IPR013154. ADH_GroES-like. IPR000794. Beta-ketoacyl_synthase. IPR002198. DH_sc/Rdtase_SDR. IPR011032. GroES-like. IPR018201. Ketoacyl_synth_AS. IPR014031. Ketoacyl_synth_C. IPR014030. Ketoacyl_synth_N. IPR016036. Malonyl_transacylase_ACP-bd. IPR016040. NAD(P)-bd_dom. IPR006163. Phsphopanteth-bd. IPR020842. PKS/FAS_KR. IPR020801. PKS_acyl_transferase. IPR020841. PKS_Beta-ketoAc_synthase_dom. IPR020807. PKS_dehydratase. IPR020843. PKS_ER. IPR013968. PKS_KR. IPR020806. PKS_PP-bd. IPR006162. PPantetheine_attach_site. IPR002364. Quin_OxRdtase/zeta-crystal_CS. IPR016039. Thiolase-like. IPR016038. Thiolase-like_subgr. [Graphical view]
Gene3D	G3DSA:3.40.366.10. Ac_transferase_reg. 12 hits. G3DSA:1.10.1200.10. ACP_like. 6 hits. G3DSA:3.40.50.720. NAD(P)-bd. 7 hits. G3DSA:3.40.47.10. Thiolase-like_subgr. 12 hits.
PANTHER	PTHR11712. Ketoacyl_synth. 1 hit.
Pfam	PF00698. Acyl_transf_1. 6 hits. PF08240. ADH_N. 1 hit. PF00106. adh_short. 2 hits. PF00107. ADH_zinc_N. 1 hit. PF00109. ketoacyl-synt. 6 hits. PF02801. Ketoacyl-synt_C. 6 hits. PF08659. KR. 4 hits. PF00550. PP-binding. 6 hits. [Graphical view]
SMART	SM00827. PKS_AT. 6 hits. SM00826. PKS_DH. 6 hits. SM00829. PKS_ER. 1 hit. SM00822. PKS_KR. 6 hits. SM00825. PKS_KS. 6 hits. SM00823. PKS_PP. 6 hits. [Graphical view]
SUPFAM	SSF47336. ACP_like. 6 hits. SSF52151. Acyl_Trfase/lysoPlipase. 6 hits. SSF50129. GroES_like. 1 hit. SSF55048. Malonyl_transacylase_ACP-bd. 6 hits. SSF53901. Thiolase-like. 6 hits.
PROSITE	PS50075. ACP_DOMAIN. 6 hits. PS00606. B_KETOACYL_SYNTHASE. 6 hits. PS00012. PHOSPHOPANTETHEINE. 5 hits. PS01162. QOR_ZETA_CRYSTAL. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9L4W3_9ACTO

Accession

Primary (citable) accession number: Q9L4W3

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2000
Last sequence update:	October 1, 2000
Last modified:	December 14, 2011
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)