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Protein
Submitted name:

Sigma-54-dependent transcriptional activator

Gene

prdR

Organism
Acetoanaerobium sticklandii (Clostridium sticklandii)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi301 – 308ATPPROSITE-ProRule annotation8
Nucleotide bindingi364 – 373ATPPROSITE-ProRule annotation10

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingSAAS annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandATP-bindingPROSITE-ProRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Sigma-54-dependent transcriptional activatorImported
Gene namesi
Name:prdRImported
OrganismiAcetoanaerobium sticklandii (Clostridium sticklandii)Imported
Taxonomic identifieri1511 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesPeptostreptococcaceaeAcetoanaerobium

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliQ9L4Q6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini15 – 71CBSInterPro annotationAdd BLAST57
Domaini77 – 137CBSInterPro annotationAdd BLAST61
Domaini134 – 185PAS (PER-ARNT-SIM)InterPro annotationAdd BLAST52
Domaini273 – 502Sigma-54 factor interactionInterPro annotationAdd BLAST230

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili239 – 266Sequence analysisAdd BLAST28

Keywords - Domaini

CBS domainPROSITE-ProRule annotation, Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG4108JUB. Bacteria.
COG3829. LUCA.

Family and domain databases

InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR000644. CBS_dom.
IPR009057. Homeobox-like.
IPR002197. HTH_Fis.
IPR027417. P-loop_NTPase.
IPR000014. PAS.
IPR002078. Sigma_54_int.
IPR025662. Sigma_54_int_dom_ATP-bd_1.
IPR025943. Sigma_54_int_dom_ATP-bd_2.
IPR025944. Sigma_54_int_dom_CS.
PfamiView protein in Pfam
PF00571. CBS. 2 hits.
PF02954. HTH_8. 1 hit.
PF13426. PAS_9. 1 hit.
PF00158. Sigma54_activat. 1 hit.
PRINTSiPR01590. HTHFIS.
SMARTiView protein in SMART
SM00382. AAA. 1 hit.
SM00116. CBS. 2 hits.
SM00091. PAS. 1 hit.
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF55785. SSF55785. 1 hit.
TIGRFAMsiTIGR00229. sensory_box. 1 hit.
PROSITEiView protein in PROSITE
PS51371. CBS. 2 hits.
PS50112. PAS. 1 hit.
PS00675. SIGMA54_INTERACT_1. 1 hit.
PS00676. SIGMA54_INTERACT_2. 1 hit.
PS00688. SIGMA54_INTERACT_3. 1 hit.
PS50045. SIGMA54_INTERACT_4. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9L4Q6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFFNQTKRLK VKEIMSKDFI VFDSDISLRR CVEHIALNNL KEVIVRHHEK
60 70 80 90 100
LTGYIKFDDI IKISLSQSFS EKKLFDIRAN KPFYLNVEDT VLMAKDIMRE
110 120 130 140 150
NQVDRVFVLD DEKLVGVLRT QDIVYKLYPK IQANEDLYEL LWDNVHEGIC
160 170 180 190 200
IIDNKGMVCI WGRGSEKLYG IKKSEIIGKK LEEFFPTALL LDVLKSKEPV
210 220 230 240 250
ENIIHSPRKN TYVNISALPL IKNGKLIGVV STERDVSEIT NLSRELEFTK
260 270 280 290 300
EKLDYLQVEV RKMNEDKFSF GNIVGKSKIM THTIDRAYQV ASTTSSVLIS
310 320 330 340 350
GESGTGKEVF ARAIHQSSGR EGAFVAINCS AIPESLFESE MFGYESGAFT
360 370 380 390 400
GALSKGKIGK IEIANGGTLF LDEIGDMPLH MQAKLLRVLQ ERQLMRVGGD
410 420 430 440 450
KSISLDVRVI SATHRNLEDM VKSGTFREDL YYRLNVVNIK LPSLSDRIED
460 470 480 490 500
VPLFVKLFIE EFCRENHMKV PNISPEILNM LMNYSWPGNI RELKNMVEHL
510 520 530 540 550
VVFSKNNEIQ IDTLPEYINN KEDKTINIKN EKSLTDLIRK TEIKAIHDAM
560 570 580
KECGNNKQQA AKLLDIPRST LYYKIKFYDL NQYL
Length:584
Mass (Da):67,033
Last modified:October 1, 2000 - v1
Checksum:iEF1F80779877F721
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ130879 Genomic DNA. Translation: CAB71309.1.
RefSeqiWP_013362446.1. NC_014614.1.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ9L4Q6_ACEST
AccessioniPrimary (citable) accession number: Q9L4Q6
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: July 5, 2017
This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)