Q9L4K1 (BETB_CHRSD) Reviewed, UniProtKB/Swiss-Prot
Last modified
April 3, 2013.
Version 55.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Betaine aldehyde dehydrogenase Short name=BADH EC=1.2.1.8 | ||
| Gene names |
| ||
| Organism | Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768) | ||
| Taxonomic identifier | 290398 [NCBI] | ||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Oceanospirillales › Halomonadaceae › Chromohalobacter › ![]() |
Protein attributes
| Sequence length | 489 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Catalytic activity | Betaine aldehyde + NAD+ + H2O = betaine + NADH. HAMAP-Rule MF_00804 |
| Pathway | Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine from betaine aldehyde: step 1/1. HAMAP-Rule MF_00804 |
| Sequence similarities | Belongs to the aldehyde dehydrogenase family. |
Ontologies
| Keywords | |
|---|---|
| Ligand | NAD |
| Molecular function | Oxidoreductase |
| Gene Ontology (GO) | |
| Biological_process | glycine betaine biosynthetic process from choline Inferred from electronic annotation. Source: HAMAP |
| Molecular_function | betaine-aldehyde dehydrogenase activity Inferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 489 | 489 | Betaine aldehyde dehydrogenase HAMAP-Rule MF_00804 | PRO_0000056545 | |||||
Regions | |||||||||
| Nucleotide binding | 228 – 233 | 6 | NAD By similarity | ||||||
Sites | |||||||||
| Active site | 251 | 1 | By similarity | ||||||
| Active site | 285 | 1 | By similarity | ||||||
Sequences
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References
| [1] | "Genes for the synthesis of the osmoprotectant glycine betaine from choline in the moderately halophilic bacterium Halomonas elongata DSM 3043." Canovas D., Vargas C., Kneip S., Moron M.J., Ventosa A., Bremer E., Nieto J.J. Microbiology 146:455-463(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AJ238780 Genomic DNA. Translation: CAB77175.1. |
3D structure databases | |
| ProteinModelPortal | Q9L4K1. |
| SMR | Q9L4K1. Positions 8-489. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Enzyme and pathway databases | |
| UniPathway | UPA00529; UER00386. |
Family and domain databases | |
| Gene3D | 3.40.309.10. 1 hit. 3.40.605.10. 1 hit. |
| HAMAP | MF_00804. BADH. |
| InterPro | IPR016161. Ald_DH/histidinol_DH. IPR016163. Ald_DH_C. IPR016160. Ald_DH_CS. IPR016162. Ald_DH_N. IPR015590. Aldehyde_DH_dom. IPR011264. Betaine_Ald_DH. [Graphical view] |
| Pfam | PF00171. Aldedh. 1 hit. [Graphical view] |
| SUPFAM | SSF53720. Aldehyde_DH/Histidinol_DH. 1 hit. |
| TIGRFAMs | TIGR01804. BADH. 1 hit. |
| PROSITE | PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit. PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | BETB_CHRSD | ||||||||
| Accession | Primary (citable) accession number: Q9L4K1 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with
