Reviewed, UniProtKB/Swiss-Prot Q9L473 (SELD2_EUBAC)

Names and origin

Protein names

Recommended name:
    Selenide, water dikinase 2
    EC=2.7.9.3
Alternative name(s):
    Selenophosphate synthetase 2
    Selenium donor protein 2

Gene names

Name:

selD2

Organism

Eubacterium acidaminophilum

Taxonomic identifier

1731 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Eubacteriaceae › Eubacterium

Protein attributes

Sequence length	367 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Synthesizes selenophosphate from selenide and ATP By similarity.
Catalytic activity	ATP + selenide + H2O = AMP + selenophosphate + phosphate. HAMAP MF_00625
Cofactor	Magnesium By similarity.
Sequence similarities	Belongs to the selenophosphate synthetase 1 family. Class I subfamily.

Ontologies

Keywords
Coding sequence diversity	Selenocysteine
Ligand	ATP-binding Magnesium Nucleotide-binding Selenium
Molecular function	Kinase Transferase
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: HAMAP selenide, water dikinase activity Inferred from electronic annotation. Source: HAMAP selenium binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 367	367	Selenide, water dikinase 2 HAMAP MF_00625		PRO_0000127624
Regions
	Nucleotide binding	249 – 255	7	ATP Potential
Sites
	Active site	38	1	Potential
	Site	41	1	Important for catalytic activity By similarity
Amino acid modifications
	Non-standard residue	38	1	Selenocysteine HAMAP MF_00625

Sequences

	Sequence		Length	Mass (Da)
	Q9L473-1 [UniParc]. Last modified February 26, 2008. Version 2. Checksum: 7395C5C3A7922631	FASTA	367	39,584
	10 20 30 40 50 60 MDIKKLKLHH RLETNKLKTN KHYEEEVKLT QMVRAAGUAA KLGPEYLAKA LEIIPQVFNK 70 80 90 100 110 120 DLLVGYEHSD DAAVYRINSE TALILTLDFF TPVVDDPYLF GLISATNSLS DVYAMGGKPL 130 140 150 160 170 180 VAMNIVCFPA CKDVGILAQI LKGGFDKVQE SGAILVGGHS VDDNEPKYGL SVCGIVHPGR 190 200 210 220 230 240 VLSNSAAKVG DVLVLTKPLG TGIINTGIKA GIVGQQTVDE VVKIMTHLNK YAALAFDDIR 250 260 270 280 290 300 VNSATDVTGF GFLGHTMEMA RGSDVTIEIT VAQIPFIAET EELAKSGIIP AGAYRNRDFV 310 320 330 340 350 360 KNDVRMEGIA DHISDILYDP QTAGGLLVSV PENDAKALVA KMLAYGSLDA RIVGRVIPKA DKYVIVR

References

[1]	"A selDABC cluster for selenocysteine incorporation in Eubacterium acidaminophilum." Gursinsky T., Jaeger J., Andreesen J.R., Soehling B. Arch. Microbiol. 174:200-212(2000) [PubMed: 11041351] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 49065 / DSM 3953 / al-2.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AJ249161 Genomic DNA. Translation: CAB53511.1.
3D structure databases
ModBase	Search...
Enzyme and pathway databases
BRENDA	2.7.9.3. 256975.
Family and domain databases
HAMAP	MF_00625. [Tree]
InterPro	IPR000728. AIR_synth. IPR010918. AIR_synth_C. IPR004536. SelD. [Graphical view]
Pfam	PF00586. AIRS. 1 hit. PF02769. AIRS_C. 1 hit. [Graphical view]
PIRSF	PIRSF036407. Selenphspht_syn. 1 hit.
TIGRFAMs	TIGR00476. selD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SELD2_EUBAC

Accession

Primary (citable) accession number: Q9L473

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 25, 2003
Last sequence update:	February 26, 2008
Last modified:	January 20, 2009
This is version 33 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)