ID   Q9L2J2_STRCO            Unreviewed;       375 AA.
AC   Q9L2J2;
DT   01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2000, sequence version 1.
DT   27-MAR-2024, entry version 106.
DE   SubName: Full=Integral membrane protein {ECO:0000313|EMBL:CAB69689.1};
GN   OrderedLocusNames=SCO0717 {ECO:0000313|EMBL:CAB69689.1};
GN   ORFNames=SCF42.27 {ECO:0000313|EMBL:CAB69689.1};
OS   Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
OX   NCBI_TaxID=100226 {ECO:0000313|EMBL:CAB69689.1, ECO:0000313|Proteomes:UP000001973};
RN   [1] {ECO:0000313|EMBL:CAB69689.1, ECO:0000313|Proteomes:UP000001973}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-471 / A3(2) / M145
RC   {ECO:0000313|Proteomes:UP000001973};
RX   PubMed=12000953; DOI=10.1038/417141a;
RA   Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L.,
RA   Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA   Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA   Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H.,
RA   Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E.,
RA   Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D.,
RA   Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA   Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.;
RT   "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT   A3(2).";
RL   Nature 417:141-147(2002).
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DR   EMBL; AL939106; CAB69689.1; -; Genomic_DNA.
DR   RefSeq; NP_625022.1; NC_003888.3.
DR   RefSeq; WP_011027313.1; NZ_VNID01000004.1.
DR   AlphaFoldDB; Q9L2J2; -.
DR   STRING; 100226.gene:17758300; -.
DR   PaxDb; 100226-SCO0717; -.
DR   PATRIC; fig|100226.15.peg.705; -.
DR   eggNOG; COG2208; Bacteria.
DR   HOGENOM; CLU_045535_1_1_11; -.
DR   InParanoid; Q9L2J2; -.
DR   OrthoDB; 3210173at2; -.
DR   PhylomeDB; Q9L2J2; -.
DR   Proteomes; UP000001973; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016791; F:phosphatase activity; IBA:GO_Central.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   PANTHER; PTHR43156:SF2; MULTIDOMAIN REGULATORY PROTEIN RV1364C; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001973};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        64..84
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        96..113
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          146..362
FT                   /note="PPM-type phosphatase"
FT                   /evidence="ECO:0000259|SMART:SM00331"
SQ   SEQUENCE   375 AA;  39304 MW;  FE9D3CF770B187D0 CRC64;
     MRKVSAPPRR GEDRRSWLSG APPPRWVRVL PPALVAAICA ATLLSDEPLE IGFLLGAIPP
     LAVLSYGPLA TAVLGGVVIV LLHIPALQLD RPGDADLLTI VFVAVLSVFV SFVRSRRDAQ
     LGLERTVAEA AQHAVVPPLP ERVGAVRCAG LYRAAQRGTL VGGDFFDVRD GPFGVRAVMG
     DVQGHGLSAV STVASLLGAF REAVLDQADL AAVAGRLDRR LLVDSADARH AELFATAALL
     EFSADALEVR VVVCGNPPPL LLRGADAAEL EVSPWTPLGL GLADAGAIEA CTVSLRPGDR
     LFLASDGVVE ARDGSGAYYP LARRLSGLAG EDSAALPDLV WADLARFCPD VQDDVTILVL
     TPSPPALRMR GPVPH
//