ID   Q9L255_STRCO            Unreviewed;       903 AA.
AC   Q9L255;
DT   01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2000, sequence version 1.
DT   27-MAR-2024, entry version 131.
DE   RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE            EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN   OrderedLocusNames=SCO2666 {ECO:0000313|EMBL:CAB71204.1};
GN   ORFNames=SC6D10.09 {ECO:0000313|EMBL:CAB71204.1};
OS   Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
OX   NCBI_TaxID=100226 {ECO:0000313|EMBL:CAB71204.1, ECO:0000313|Proteomes:UP000001973};
RN   [1] {ECO:0000313|EMBL:CAB71204.1, ECO:0000313|Proteomes:UP000001973}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-471 / A3(2) / M145
RC   {ECO:0000313|Proteomes:UP000001973};
RX   PubMed=12000953; DOI=10.1038/417141a;
RA   Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L.,
RA   Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA   Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA   Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H.,
RA   Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E.,
RA   Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D.,
RA   Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA   Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.;
RT   "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT   A3(2).";
RL   Nature 417:141-147(2002).
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DR   EMBL; AL939113; CAB71204.1; -; Genomic_DNA.
DR   RefSeq; NP_626901.1; NC_003888.3.
DR   RefSeq; WP_011028497.1; NZ_VNID01000020.1.
DR   AlphaFoldDB; Q9L255; -.
DR   STRING; 100226.gene:17760272; -.
DR   PaxDb; 100226-SCO2666; -.
DR   PATRIC; fig|100226.15.peg.2714; -.
DR   eggNOG; COG0457; Bacteria.
DR   eggNOG; COG0515; Bacteria.
DR   HOGENOM; CLU_011707_0_0_11; -.
DR   InParanoid; Q9L255; -.
DR   OrthoDB; 137117at2; -.
DR   PhylomeDB; Q9L255; -.
DR   Proteomes; UP000001973; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IBA:GO_Central.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd14014; STKc_PknB_like; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR031634; PknG_rubred.
DR   InterPro; IPR031636; PknG_TPR.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR24363; SERINE/THREONINE PROTEIN KINASE; 1.
DR   PANTHER; PTHR24363:SF0; SERINE_THREONINE-PROTEIN KINASE DDB_G0277989-RELATED; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   Pfam; PF16919; PknG_rubred; 1.
DR   Pfam; PF16918; PknG_TPR; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:CAB71204.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001973};
KW   Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527,
KW   ECO:0000313|EMBL:CAB71204.1}; Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          206..495
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
FT   REGION          48..127
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          508..535
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        60..122
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   903 AA;  94154 MW;  F864E323590834ED CRC64;
     MSEAGRTCQR PGCGGTYEDM GGGELYCDTC GLAPVVAAGG ALGATPTGVT GGGGSGGSRG
     SRGASGSGGS RSSARSSRTS SQSSRSSKSR RSVSGRLSRA VSGRSTGRSV SVRSSGSSAG
     STGRGRLGVG LVEVPAVPRP DPRVMVMDHP EVPERKRFCS RSDCGAPVGR SRGERPGRTE
     GFCTKCGHPY SFVPKLKAGD VVHGQYEVVG CLAHGGLGWI YLAVDKAVSD RWVVLKGLLD
     TGDQDAMAAA ISERRFLAEI EHANIVRIYN FVEHLDQRTG SLDGYIVMEY VGGKSLKEIA
     NARRSPQGRR DPLPVEQACA YGIEALEALG HLHSRKLLYC DFKVDNAIQT EDQLKLIDMG
     AVRRMDDDES AIYGTVGYQA PEVADVGPSV ASDLYTVGRT LAVLSFDFQG YTTVYADSLP
     DPDSIEVFRQ YESFYRLLVR ATDPDPARRF ASAQEMAEQL TGVLREVVSL QTGRARPAVS
     TLFGPEVRVT DTELFPRLDG EVSRLGARVP PARGRRGGSG AALPGGAGAA PALPGGSGPA
     VGAPGGTVAH APPVGAGTPV AASGGASASL PGAVSSAGSA GWLGTGASGL VKEADAPTAS
     LTLPVPRVDA GDPNAGFLAG LMASAPAELL TALAAAPAPS TETRLRQIRA RLENGDASGA
     LEALGALEGE RPDDWRVVWY RGLAALVTGA HEDAALAFDA IYDAFPGEIA PKLALGLCAE
     VLGQLDNAAE YYRLVWSSDP SHVSAAFGLA RVQLAAGDRA AAVRTLESVP ESSVHCTAAR
     VAAVRARLRQ RTAAAGDLRF LDDLIAAARQ VEALDVYGLD PARREQLSAE VLGCALDWVL
     SGGRGSVPPA AGGRTLLGSG LDERGLRFGL ERSYRTLARL ARGGEERIDL VERANRYRPR
     TWV
//