Q9L1J1 (Q9L1J1_STRCO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Methylmalonic acid semialdehyde dehydrogenase EMBL CAB75315.1

Gene names

Name:	msdA
Ordered Locus Names:	SCO2726

Organism

Streptomyces coelicolor

Taxonomic identifier

1902 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptomycineae › Streptomycetaceae › Streptomyces

Protein attributes

Sequence length	500 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the aldehyde dehydrogenase family. RuleBase RU003345

Ontologies

Keywords
Molecular function	Oxidoreductase RuleBase RU003344
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	methylmalonate-semialdehyde dehydrogenase (acylating) activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9L1J1 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 089F3B4AC57F6C19	FASTA	500	52,573
	10 20 30 40 50 60 MTNIVNHWIG GKTAEGASGT YGPVTNPATG EVTTKVAFAS VDEVDAAVAA AREAYLTWGQ 70 80 90 100 110 120 SSLAQRTSIL FRFRALLDAH RDEIAELITA EHGKVHSDAL GEVARGLEIV DLACGINVQL 130 140 150 160 170 180 KGELSTQVAT RVDVSSIRQP LGVVAGITPF NFPAMVPLWM FPIAIACGNT FVLKPSEKDP 190 200 210 220 230 240 SAAVKVAELL SEAGLPDGVF NVVHGDKVAV DRLLEHPDVK AVSFVGSTPI ARYIHTTASA 250 260 270 280 290 300 NGKRVQALGG AKNHMLVLPD ADLDAAADAA VSAAYGSAGE RCMAISAVVA VGAVGDELVE 310 320 330 340 350 360 KIRERAEKIK IGPGTDPSSE MGPLITKAHR DKVASYVAGA AAEGCEVVLD GTGYTVDGHE 370 380 390 400 410 420 DGHWIGISLL DRVPTTAKAY QDEIFGPVLC VLRADTYEEG VALINASPFG NGTAIFTRDG 430 440 450 460 470 480 GAARRFQLEI EAGMVGVNVP IPVPVGYHSF GGWKDSLFGD HHIYGNDGTH FYTRGKVVTT 490 500 RWPDPADAPA GVDLGFPRNH

References

[1]

"Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)." Bentley S.D., Chater K.F., Cerdeno-Tarraga A.-M., Challis G.L., Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D., Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A., Fraser A., Goble A. , Hidalgo J., Hornsby T., Howarth S., Huang C.-H., Kieser T., Larke L., Murphy L.D., Oliver K., O'Neil S., Rabbinowitsch E., Rajandream M.A., Rutherford K.M., Rutter S., Seeger K., Saunders D., Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A., Woodward J.R., Barrell B.G., Parkhill J., Hopwood D.A. Nature 417:141-147(2002) [PubMed: 12000953] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-471 / A3(2) / M145.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL939113 Genomic DNA. Translation: CAB75315.1.
RefSeq	NP_626959.1. NC_003888.3.
3D structure databases
HSSP	HSSP built from PDB template 1O01 based on UniProtKB P05091.
ProteinModelPortal	Q9L1J1.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1098160.
GenomeReviews	Gene locus SCO2726 in contig AL645882_GR.
KEGG	sco:SCO2726.
NMPDR	fig|100226.1.peg.2691.
PATRIC	23735164. VBIStrCoe124346_2782.
Phylogenomic databases
HOGENOM	HBG752218.
OMA	HWIGGKT.
PhylomeDB	Q9L1J1.
ProtClustDB	CLSK635640.
Family and domain databases
InterPro	IPR016161. Ald_DH/histidinol_DH. IPR016163. Ald_DH_C. IPR016160. Ald_DH_CS. IPR016162. Ald_DH_N. IPR015590. Aldehyde_DH_dom. IPR010061. MeMal-semiAld_DH. [Graphical view]
Gene3D	G3DSA:3.40.309.10. Aldehyde_dehydrogenase_C. 1 hit. G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
KO	K00140.
PANTHER	PTHR11699:SF27. MMSDH. 1 hit.
Pfam	PF00171. Aldedh. 1 hit. [Graphical view]
SUPFAM	SSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
TIGRFAMs	TIGR01722. MMSDH. 1 hit.
PROSITE	PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9L1J1_STRCO

Accession

Primary (citable) accession number: Q9L1J1

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2000
Last sequence update:	October 1, 2000
Last modified:	December 14, 2011
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)