ID   Q9L0Z1_STRCO            Unreviewed;       774 AA.
AC   Q9L0Z1;
DT   01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2000, sequence version 1.
DT   27-MAR-2024, entry version 125.
DE   RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE            EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN   OrderedLocusNames=SCO1468 {ECO:0000313|EMBL:CAB76890.1};
GN   ORFNames=SCL6.25c {ECO:0000313|EMBL:CAB76890.1};
OS   Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
OX   NCBI_TaxID=100226 {ECO:0000313|EMBL:CAB76890.1, ECO:0000313|Proteomes:UP000001973};
RN   [1] {ECO:0000313|EMBL:CAB76890.1, ECO:0000313|Proteomes:UP000001973}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-471 / A3(2) / M145
RC   {ECO:0000313|Proteomes:UP000001973};
RX   PubMed=12000953; DOI=10.1038/417141a;
RA   Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L.,
RA   Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA   Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA   Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H.,
RA   Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E.,
RA   Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D.,
RA   Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA   Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.;
RT   "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT   A3(2).";
RL   Nature 417:141-147(2002).
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DR   EMBL; AL939109; CAB76890.1; -; Genomic_DNA.
DR   RefSeq; NP_625749.1; NC_003888.3.
DR   AlphaFoldDB; Q9L0Z1; -.
DR   STRING; 100226.gene:17759054; -.
DR   PaxDb; 100226-SCO1468; -.
DR   PATRIC; fig|100226.15.peg.1477; -.
DR   eggNOG; COG0515; Bacteria.
DR   HOGENOM; CLU_011707_0_0_11; -.
DR   InParanoid; Q9L0Z1; -.
DR   OrthoDB; 137117at2; -.
DR   PhylomeDB; Q9L0Z1; -.
DR   Proteomes; UP000001973; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IBA:GO_Central.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR031634; PknG_rubred.
DR   InterPro; IPR031636; PknG_TPR.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR24363; SERINE/THREONINE PROTEIN KINASE; 1.
DR   PANTHER; PTHR24363:SF0; SERINE_THREONINE-PROTEIN KINASE DDB_G0277989-RELATED; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   Pfam; PF16919; PknG_rubred; 1.
DR   Pfam; PF16918; PknG_TPR; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:CAB76890.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001973};
KW   Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527,
KW   ECO:0000313|EMBL:CAB76890.1}; Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          131..493
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
FT   REGION          1..83
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        16..36
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   774 AA;  83436 MW;  88FAE0E62CB2E8F2 CRC64;
     MVTGFCDTCF RRPLAPEPTA TPPDPDPDPA GPDARGPRPA QGPGAPAAGE LDRDGLLVLP
     HLPSPDPSEA ADTVARPPTG GRRCGVDNCA GTIGVSYDGG PAPDHGFCPE CGTEYSFRPK
     LRPGDRVAGH YAVLGYLAVG GHGWVYLAED TRVPGLHVVL KGLINTGDAV ARRAAVEERR
     SLTTLHHRDI VRIVTHVQHQ VPGDAEPTGY IVMEYVGGRS LSWIRFAPEE ELARLFGTGG
     FEFGHVITYG CKILGALEYL HDRGLLYCDM KPENVIHYGR EIKVIDLGAI RRIDDRSSGL
     VHTHGYAPPK RERDRRGLDV DSDLYTVGRT LKVLAERAAR PAGLAARSFE ALIRRATHPE
     PAARFRSAAE MSRQLWEVLR EDQALGGREP YPERSTRFEP TAAVFGAALG TVPALQWWTR
     RPGTGTPELP AGAPEPRAAA RALPVPLPDA SDPAAVLLGG LAADTPDRIA ERSAGDPALR
     TVETALWLCR AYLEAGDAAR AEEWVARAKG WSGDYDWRIF WHRGLIHLTR DAVDKAEDEF
     AATYAALPGE AAPKLALGFC AEYLAERPRE SAGEGGGPAD AQAAARMRAR QAQAEEFYEA
     VLRRDPTQGS AAFGLARVRL RRAGRRPAVD VLDGVPTTSR HYDAARVAAV RILTGRLPDR
     PAPLAAELRE AAERLAGLHL DGSGSWDRLV TELREHALAC RPPGGWGSGF PAGELCGPQD
     TEEALRRLLS ASLRRLADQA GGVGERGDLL DTAYAVLPAP AGLRELVRGW RRTA
//