ID   Q9KZX9_STRCO            Unreviewed;       362 AA.
AC   Q9KZX9;
DT   01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2000, sequence version 1.
DT   27-MAR-2024, entry version 106.
DE   SubName: Full=Integral membrane protein {ECO:0000313|EMBL:CAB88454.1};
GN   OrderedLocusNames=SCO4447 {ECO:0000313|EMBL:CAB88454.1};
GN   ORFNames=SCD6.25 {ECO:0000313|EMBL:CAB88454.1};
OS   Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
OX   NCBI_TaxID=100226 {ECO:0000313|EMBL:CAB88454.1, ECO:0000313|Proteomes:UP000001973};
RN   [1] {ECO:0000313|EMBL:CAB88454.1, ECO:0000313|Proteomes:UP000001973}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-471 / A3(2) / M145
RC   {ECO:0000313|Proteomes:UP000001973};
RX   PubMed=12000953; DOI=10.1038/417141a;
RA   Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L.,
RA   Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA   Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA   Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H.,
RA   Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E.,
RA   Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D.,
RA   Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA   Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.;
RT   "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT   A3(2).";
RL   Nature 417:141-147(2002).
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DR   EMBL; AL939120; CAB88454.1; -; Genomic_DNA.
DR   RefSeq; NP_628614.1; NC_003888.3.
DR   RefSeq; WP_011029660.1; NZ_VNID01000017.1.
DR   AlphaFoldDB; Q9KZX9; -.
DR   STRING; 100226.gene:17762092; -.
DR   PaxDb; 100226-SCO4447; -.
DR   PATRIC; fig|100226.15.peg.4517; -.
DR   eggNOG; COG2208; Bacteria.
DR   HOGENOM; CLU_045535_1_1_11; -.
DR   InParanoid; Q9KZX9; -.
DR   OrthoDB; 4935951at2; -.
DR   PhylomeDB; Q9KZX9; -.
DR   Proteomes; UP000001973; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016791; F:phosphatase activity; IBA:GO_Central.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   PANTHER; PTHR43156:SF2; MULTIDOMAIN REGULATORY PROTEIN RV1364C; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001973};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        20..47
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        59..78
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        84..103
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          136..350
FT                   /note="PPM-type phosphatase"
FT                   /evidence="ECO:0000259|SMART:SM00331"
SQ   SEQUENCE   362 AA;  37932 MW;  D1FF801BF18FD105 CRC64;
     MTVKKSPSGP VVLSWTPVAA MAVVAVVDLT MGPGVGLLPL VSLGPAFGSL VGGWRRTAVI
     GLAALLLCVG LGMYNGLFDR PRGYTAMLSV AGVTGVGIAA AVMRSRREAE LASVRSIAEA
     AQRVLLRPVP LTAGPLHAAV SYTSAVAEAR IGGDLYEVVA SPHGVRVIVG DVQGKGLAAV
     ETAARVLGAF REAAYDEEDL VELGERLERS VARELEDEKF VTAILAEIGH DHRVVLLNYG
     HPAPLLVHGD GTADFPEPPA YALPLGLAAH GGPGPDPFPV PFRPGDQLLL YTDGVTEARD
     ERGGFYPLAE RAHLLKDPDI HRALDALRED LVRHAAGPHH DDAAMLLLRY QQGAGATPST
     PA
//