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Protein
Submitted name:

Isocitrate dehydrogenase

Gene

SCO7000

Organism
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Cofactori

Mg2+UniRule annotation, Mn2+UniRule annotationNote: Binds 1 Mg2+ or Mn2+ ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei145SubstrateUniRule annotation1
Sitei255Critical for catalysisUniRule annotation1
Metal bindingi348Magnesium or manganeseUniRule annotation1
Sitei418Critical for catalysisUniRule annotation1
Binding sitei545SubstrateUniRule annotation1
Metal bindingi546Magnesium or manganeseUniRule annotation1
Metal bindingi550Magnesium or manganeseUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMagnesiumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenaseImported
Gene namesi
Ordered Locus Names:SCO7000Imported
OrganismiStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)Imported
Taxonomic identifieri100226 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomycesStreptomyces albidoflavus group
Proteomesi
  • UP000001973 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi100226.SCO7000

Structurei

3D structure databases

ProteinModelPortaliQ9KZF3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni132 – 139Substrate bindingUniRule annotation8

Phylogenomic databases

eggNOGiCOG2838 LUCA
HOGENOMiHOG000240860
InParanoidiQ9KZF3
KOiK00031
OMAiRDSGKMW
OrthoDBiPOG091H0B3N
PhylomeDBiQ9KZF3

Family and domain databases

InterProiView protein in InterPro
IPR004436 Isocitrate_DH_NADP_mono
PANTHERiPTHR36999 PTHR36999, 1 hit
PfamiView protein in Pfam
PF03971 IDH, 1 hit
PIRSFiPIRSF009407 IDH_monmr, 1 hit
TIGRFAMsiTIGR00178 monomer_idh, 1 hit

Sequencei

Sequence statusi: Complete.

Q9KZF3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDSTIIYTH TDEAPALATY SFLPVVRAYA SQAGVAVETR DISLAGRIIA
60 70 80 90 100
LFPEYLTEDQ RIPDALAELG ELAKTPAANI IKLPNISASI PQLKAAVAEL
110 120 130 140 150
QGQGYALPAY PDDPKTDEER DIRARYDKVK GSAVNPVLRE GNSDRRAPAS
160 170 180 190 200
VKNYAKTHPH RMGAWTGESK TNVATMGEND FRSTEKSAVI AEDGTLRIEL
210 220 230 240 250
VGDDGTTTVL RESVPVKKDE VVDASVLRVA ALREFLTAQV ARAKAEGILY
260 270 280 290 300
SVHLKATMMK VSDPIIFGHV VRAFFPKTFA QYGDVLAKAG LTPNDGLGGI
310 320 330 340 350
YKGLESLPEG AEIKASFDAE LAEGPELAMV DSDKGITNLH VPSDVIIDAS
360 370 380 390 400
MPAMIRTSGH MWGADGGEHD ALAVIPDSSY AGVYQAVIED CRANGAYDPS
410 420 430 440 450
TMGSVPNVGL MAQKAEEYGS HDKTFEIPTT GTVRLVDAAG NAVLEQTVSA
460 470 480 490 500
GDIFRACQTK DAPIRDWVKL AVTRARATGD PAVFWLDEGR AHDANLIAKV
510 520 530 540 550
KQYLSEHDTE GLDIRILDPV EATKLSVERI RRGENTISVT GNVLRDYLTD
560 570 580 590 600
LFPILELGTS AKMLSVVPLM AGGGLFETGA GGSAPKHVQQ LVKEDYLRWD
610 620 630 640 650
SLGEFFALVP SLEKYAEATG NGKAKVLADT LDRATATFLN EDKSPTRRVG
660 670 680 690 700
GIDNRGSHFY LSLYWAQELA KQTDDADLAK AFAPLAETLT ASEQKIVEEL
710 720 730
NAVQGKPAEI GGYYQPDPAK AAKIMRPSTT WNEALASLA
Length:739
Mass (Da):79,520
Last modified:October 1, 2000 - v1
Checksum:iFCDF3F1D006AFC2D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL939130 Genomic DNA Translation: CAB88977.1
RefSeqiNP_631065.1, NC_003888.3
WP_011031369.1, NC_003888.3

Genome annotation databases

EnsemblBacteriaiCAB88977; CAB88977; CAB88977
GeneIDi1102438
KEGGisco:SCO7000
PATRICifig|100226.15.peg.7102

Similar proteinsi

Entry informationi

Entry nameiQ9KZF3_STRCO
AccessioniPrimary (citable) accession number: Q9KZF3
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: May 23, 2018
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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