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Protein

Succinyl-CoA ligase [ADP-forming] subunit alpha

Gene

SCO4809

Organism
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + succinate + CoA = ADP + phosphate + succinyl-CoA.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei251 – 2511Tele-phosphohistidine intermediateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Succinyl-CoA ligase [ADP-forming] subunit alphaUniRule annotation (EC:6.2.1.5UniRule annotation)
Gene namesi
Ordered Locus Names:SCO4809Imported
OrganismiStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)Imported
Taxonomic identifieri100226 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomycesStreptomyces albidoflavus group
Proteomesi
  • UP000001973 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ9KY55.

Interactioni

Subunit structurei

Heterotetramer of two alpha and two beta subunits.UniRule annotation

Protein-protein interaction databases

STRINGi100226.SCO4809.

Structurei

3D structure databases

ProteinModelPortaliQ9KY55.
SMRiQ9KY55. Positions 3-290.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini4 – 104101CoA_bindingInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the succinate/malate CoA ligase alpha subunit family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CH8. Bacteria.
COG0074. LUCA.
HOGENOMiHOG000239685.
InParanoidiQ9KY55.
KOiK01902.
OMAiFEQDPQT.
OrthoDBiEOG644ZT0.
PhylomeDBiQ9KY55.

Family and domain databases

Gene3Di3.40.50.261. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR017440. Cit_synth/succinyl-CoA_lig_AS.
IPR003781. CoA-bd.
IPR005810. CoA_lig_alpha.
IPR005811. CoA_ligase.
IPR016040. NAD(P)-bd_dom.
IPR016102. Succinyl-CoA_synth-like.
[Graphical view]
PfamiPF02629. CoA_binding. 1 hit.
PF00549. Ligase_CoA. 1 hit.
[Graphical view]
PIRSFiPIRSF001553. SucCS_alpha. 1 hit.
PRINTSiPR01798. SCOASYNTHASE.
SMARTiSM00881. CoA_binding. 1 hit.
[Graphical view]
SUPFAMiSSF51735. SSF51735. 1 hit.
SSF52210. SSF52210. 1 hit.
TIGRFAMsiTIGR01019. sucCoAalpha. 1 hit.
PROSITEiPS01216. SUCCINYL_COA_LIG_1. 1 hit.
PS00399. SUCCINYL_COA_LIG_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9KY55-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAIWLNKDSK VIVQGMTGAT GMKHTKLMLG DGTEVVGGVN PRKAGTSVDF
60 70 80 90 100
DGNEVPVFGT VKEAIEKTGA NVSVIFVPEK FTKDAVVEAI DAEIPLAVVI
110 120 130 140 150
TEGIAVHDSA AFWSYAGKKG NKTRIIGPNC PGIITPGQSN VGIIPGDITK
160 170 180 190 200
PGRIGLVSKS GTLTYQMMYE LRDIGFSTAV GIGGDPIIGT THIDALAAFE
210 220 230 240 250
ADPETDLIVM IGEIGGDAEE RAAEYISKNV TKPVVGYVAG FTAPEGKTMG
260 270 280 290
HAGAIVSGSS GTAQAKKEAL EAAGVKVGKT PTETAKLARA ILAG
Length:294
Mass (Da):30,239
Last modified:October 1, 2000 - v1
Checksum:iECD4DC830CAE8F09
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL939121 Genomic DNA. Translation: CAB92672.1.
RefSeqiNP_628966.1. NC_003888.3.
WP_003974163.1. NC_003888.3.

Genome annotation databases

EnsemblBacteriaiCAB92672; CAB92672; CAB92672.
GeneIDi1100250.
KEGGisco:SCO4809.
PATRICi23739452. VBIStrCoe124346_4886.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL939121 Genomic DNA. Translation: CAB92672.1.
RefSeqiNP_628966.1. NC_003888.3.
WP_003974163.1. NC_003888.3.

3D structure databases

ProteinModelPortaliQ9KY55.
SMRiQ9KY55. Positions 3-290.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi100226.SCO4809.

Proteomic databases

PRIDEiQ9KY55.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB92672; CAB92672; CAB92672.
GeneIDi1100250.
KEGGisco:SCO4809.
PATRICi23739452. VBIStrCoe124346_4886.

Phylogenomic databases

eggNOGiENOG4105CH8. Bacteria.
COG0074. LUCA.
HOGENOMiHOG000239685.
InParanoidiQ9KY55.
KOiK01902.
OMAiFEQDPQT.
OrthoDBiEOG644ZT0.
PhylomeDBiQ9KY55.

Family and domain databases

Gene3Di3.40.50.261. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR017440. Cit_synth/succinyl-CoA_lig_AS.
IPR003781. CoA-bd.
IPR005810. CoA_lig_alpha.
IPR005811. CoA_ligase.
IPR016040. NAD(P)-bd_dom.
IPR016102. Succinyl-CoA_synth-like.
[Graphical view]
PfamiPF02629. CoA_binding. 1 hit.
PF00549. Ligase_CoA. 1 hit.
[Graphical view]
PIRSFiPIRSF001553. SucCS_alpha. 1 hit.
PRINTSiPR01798. SCOASYNTHASE.
SMARTiSM00881. CoA_binding. 1 hit.
[Graphical view]
SUPFAMiSSF51735. SSF51735. 1 hit.
SSF52210. SSF52210. 1 hit.
TIGRFAMsiTIGR01019. sucCoAalpha. 1 hit.
PROSITEiPS01216. SUCCINYL_COA_LIG_1. 1 hit.
PS00399. SUCCINYL_COA_LIG_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-471 / A3(2) / M145Imported.

Entry informationi

Entry nameiQ9KY55_STRCO
AccessioniPrimary (citable) accession number: Q9KY55
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: March 16, 2016
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.