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Q9KXS0 (KGUA_STRCO) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 80. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Guanylate kinase

EC=2.7.4.8
Alternative name(s):
GMP kinase
Gene names
Name:gmk
Ordered Locus Names:SCO1479
ORF Names:SC9C5.03c
OrganismStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) [Reference proteome] [HAMAP]
Taxonomic identifier100226 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomycesStreptomyces albidoflavus group

Protein attributes

Sequence length197 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Essential for recycling GMP and indirectly, cGMP By similarity. HAMAP-Rule MF_00328

Catalytic activity

ATP + GMP = ADP + GDP. HAMAP-Rule MF_00328

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00328.

Sequence similarities

Belongs to the guanylate kinase family.

Contains 1 guanylate kinase-like domain.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processpurine nucleotide metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

guanylate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 197197Guanylate kinase HAMAP-Rule MF_00328
PRO_0000170615

Regions

Domain17 – 197181Guanylate kinase-like
Nucleotide binding24 – 318ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9KXS0 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 318741E08824DC53

FASTA19721,734
        10         20         30         40         50         60 
MAATPRGTSP VPPDARPRLT VLSGPSGVGK STVVAHMRKE HPEVWLSVSA TTRRPRPGEQ 

        70         80         90        100        110        120 
HGVHYFFVSD EEMDKLIANG ELLEWAEFAG NRYGTPRTAV LERLEAGEPV LLEIDLQGAR 

       130        140        150        160        170        180 
QVRESMPEAR LVFLAPPSWD ELVRRLTGRG TEPPEVIERR LAAAKVELAA EPEFDQTLVN 

       190 
TSVEDVAREL LALTNVV 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL939109 Genomic DNA. Translation: CAB93359.1.
RefSeqNP_625759.1. NC_003888.3.

3D structure databases

ProteinModelPortalQ9KXS0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING100226.SCO1479.

Proteomic databases

PRIDEQ9KXS0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAB93359; CAB93359; CAB93359.
GeneID1096905.
KEGGsco:SCO1479.
PATRIC23732534. VBIStrCoe124346_1488.

Phylogenomic databases

eggNOGCOG0194.
HOGENOMHOG000037640.
KOK00942.
OMADAVFSIS.
OrthoDBEOG6CP410.
PhylomeDBQ9KXS0.

Family and domain databases

Gene3D3.40.50.300. 2 hits.
HAMAPMF_00328. Guanylate_kinase.
InterProIPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like.
IPR017665. Guanylate_kinase.
IPR020590. Guanylate_kinase_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamPF00625. Guanylate_kin. 1 hit.
[Graphical view]
SMARTSM00072. GuKc. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR03263. guanyl_kin. 1 hit.
PROSITEPS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameKGUA_STRCO
AccessionPrimary (citable) accession number: Q9KXS0
Entry history
Integrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: October 1, 2000
Last modified: May 14, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families