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Q9KX62 (KGUA_MYCGA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Guanylate kinase
EC=2.7.4.8
Alternative name(s):
GMP kinase
Gene names
Name:gmk
Ordered Locus Names:MYCGA6400
ORF Names:MGA_0462
OrganismMycoplasma gallisepticum (strain R(low / passage 15 / clone 2)) [Complete proteome] [HAMAP]
Taxonomic identifier710127 [NCBI]
Taxonomic lineageBacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma ›

Protein attributes

Sequence length195 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Essential for recycling GMP and indirectly, cGMP By similarity. HAMAP-Rule MF_00328

Catalytic activity

ATP + GMP = ADP + GDP. HAMAP-Rule MF_00328

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the guanylate kinase family.

Contains 1 guanylate kinase-like domain.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processpurine nucleotide metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

guanylate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 195195Guanylate kinase HAMAP-Rule MF_00328
PRO_0000170561

Regions

Domain12 – 191180Guanylate kinase-like
Nucleotide binding19 – 268ATP By similarity

Experimental info

Sequence conflict1201R → K in AAF36761. Ref.1
Sequence conflict1911L → R in AAF36761. Ref.1
Sequence conflict1941N → S in AAF36761. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Q9KX62 [UniParc].

Last modified August 15, 2003. Version 2.
Checksum: 6AB0B0FBF9A66573

FASTA19522,473
        10         20         30         40         50         60 
MVVIYIMSNK QGLIILISGP SGVGKGTIVS RLLSDNNLKL NVSISATTRK KRASEVEGVH 

        70         80         90        100        110        120 
YFFKTKEEFE QMIANNQLLE YANYVNNYYG TPLSLVKEIL DKNENLILEI EYQGVIQVLR 

       130        140        150        160        170        180 
KGFRTLSIFV LPPSEDELVA RLKKRGTEND EVIKHRLEQA VKEYAHRELY DHTIINDDLE 

       190 
KTIEDIKQLI LKYNQ

« Hide

References

« Hide 'large scale' references
[1]Skamrov A.V., Feoktistova E.S., Gol'dman M.A., Bibilashvili R.S.
Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: A5969Var.B.
[2]"The complete genome sequence of the avian pathogen Mycoplasma gallisepticum strain R(low)."
Papazisi L., Gorton T.S., Kutish G., Markham P.F., Browning G.F., Nguyen D.K., Swartzell S., Madan A., Mahairas G., Geary S.J.
Microbiology 149:2307-2316(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: R(low / passage 15 / clone 2).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		L35043 Genomic DNA. Translation: AAF36761.1.
AE015450 Genomic DNA. Translation: AAP56990.1.
RefSeqNP_853422.1. NC_004829.2.

3D structure databases

ProteinModelPortalQ9KX62.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAP56990; AAP56990; MGA_0462.
GeneID1089945.
KEGGmga:MGA_0462.
PATRIC20009175. VBIMycGal115357_0717.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0194.
HOGENOMHOG000037639.
KOK00942.
OMAEWAEFAG.

Family and domain databases

HAMAPMF_00328. Guanylate_kinase.
InterProIPR008144. Guanylate_kin.
IPR008145. Guanylate_kin/L-typ_Ca_channel.
IPR020590. Guanylate_kinase_CS.
IPR017665. Guanylate_kinase_sub.
[Graphical view]
PfamPF00625. Guanylate_kin. 1 hit.
[Graphical view]
SMARTSM00072. GuKc. 1 hit.
[Graphical view]
TIGRFAMsTIGR03263. guanyl_kin. 1 hit.
PROSITEPS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameKGUA_MYCGA
AccessionPrimary (citable) accession number: Q9KX62
Entry history
Integrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: August 15, 2003
Last modified: May 1, 2013
This is version 74 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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