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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Mycoplasma gallisepticum (strain R(low / passage 15 / clone 2))
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei282 – 2821Proton donorBy similarity
Active sitei303 – 3031By similarity
Active sitei419 – 4191By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciMGAL710127:GC09-718-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:MYCGA6360
ORF Names:MGA_0457
OrganismiMycoplasma gallisepticum (strain R(low / passage 15 / clone 2))
Taxonomic identifieri710127 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000001418 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 426426Glucose-6-phosphate isomerasePRO_0000180678Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ9KX58.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.Curated

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000100403.
KOiK01810.
OMAiKYNMFKL.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9KX58-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIKLTFNLIK GLDYKKLDKN YQAKLDEIFS QLKNKKTPSA NMLGWIDYVD
60 70 80 90 100
QDHTKIYKSI DNKITEWDKL KVTDVVVIGI GGSFTGIKAI LDVVAYLPSE
110 120 130 140 150
QKRQIHFIRS LSENSFLKIL EEVKDKNWGI VVISKSGTTL EPSVGFKLFR
160 170 180 190 200
EALYKQYGEQ AQKRIVAITD PKKGVLHDIA VKNKYEMLPI YSDIGGRFST
210 220 230 240 250
ITPSGLLVAG LVGADYKQLI EGAKKAKADL FASSELKKNS AYTYAALRHY
260 270 280 290 300
LYTEMKKDVE IAITYEEQHE YLMLQHRQLF GESEGKSLNS LFPTYSVFTT
310 320 330 340 350
DLHSMGQLYQ DGKKIFFETV FSFEKANKNK LKLKNSEFNN DDQLDYLTKK
360 370 380 390 400
SVNQLNYVAC EATKQAHASA GVPIIEIDVK ENSAYGFGYL YFWLCVATSV
410 420
SALLLGHDPY NQPGVENYKQ RMFKLL
Length:426
Mass (Da):48,484
Last modified:August 15, 2003 - v2
Checksum:i8C40A7D813D78357
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti65 – 651T → A in AAF36765 (Ref. 1) Curated
Sequence conflicti119 – 1191I → V in AAF36765 (Ref. 1) Curated
Sequence conflicti123 – 1231V → I in AAF36765 (Ref. 1) Curated
Sequence conflicti417 – 4171N → D in AAF36765 (Ref. 1) Curated
Sequence conflicti426 – 4261L → LKE in AAF36765 (Ref. 1) Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L35043 Genomic DNA. Translation: AAF36765.1.
AE015450 Genomic DNA. Translation: AAP56986.2.
RefSeqiNP_853418.2. NC_004829.2.
WP_011113896.1. NC_004829.2.

Genome annotation databases

EnsemblBacteriaiAAP56986; AAP56986; MGA_0457.
GeneIDi1089949.
KEGGimga:MGA_0457.
PATRICi20009167. VBIMycGal115357_0713.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L35043 Genomic DNA. Translation: AAF36765.1.
AE015450 Genomic DNA. Translation: AAP56986.2.
RefSeqiNP_853418.2. NC_004829.2.
WP_011113896.1. NC_004829.2.

3D structure databases

ProteinModelPortaliQ9KX58.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAP56986; AAP56986; MGA_0457.
GeneIDi1089949.
KEGGimga:MGA_0457.
PATRICi20009167. VBIMycGal115357_0713.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000100403.
KOiK01810.
OMAiKYNMFKL.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
BioCyciMGAL710127:GC09-718-MONOMER.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Skamrov A.V., Feoktistova E.S., Gol'dman M.A., Bibilashvili R.S.
    Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: A5969Var.B.
  2. "The complete genome sequence of the avian pathogen Mycoplasma gallisepticum strain R(low)."
    Papazisi L., Gorton T.S., Kutish G., Markham P.F., Browning G.F., Nguyen D.K., Swartzell S., Madan A., Mahairas G., Geary S.J.
    Microbiology 149:2307-2316(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: R(low / passage 15 / clone 2).

Entry informationi

Entry nameiG6PI_MYCGA
AccessioniPrimary (citable) accession number: Q9KX58
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 2, 2001
Last sequence update: August 15, 2003
Last modified: May 27, 2015
This is version 88 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.