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Q9KX58 (G6PI_MYCGA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 81. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:MYCGA6360
ORF Names:MGA_0457
OrganismMycoplasma gallisepticum (strain R(low / passage 15 / clone 2)) [Complete proteome] [HAMAP]
Taxonomic identifier710127 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma

Protein attributes

Sequence length426 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 426426Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180678

Sites

Active site2821Proton donor By similarity
Active site3031 By similarity
Active site4191 By similarity

Experimental info

Sequence conflict651T → A in AAF36765. Ref.1
Sequence conflict1191I → V in AAF36765. Ref.1
Sequence conflict1231V → I in AAF36765. Ref.1
Sequence conflict4171N → D in AAF36765. Ref.1
Sequence conflict4261L → LKE in AAF36765. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Q9KX58 [UniParc].

Last modified August 15, 2003. Version 2.
Checksum: 8C40A7D813D78357

FASTA42648,484
        10         20         30         40         50         60 
MIKLTFNLIK GLDYKKLDKN YQAKLDEIFS QLKNKKTPSA NMLGWIDYVD QDHTKIYKSI 

        70         80         90        100        110        120 
DNKITEWDKL KVTDVVVIGI GGSFTGIKAI LDVVAYLPSE QKRQIHFIRS LSENSFLKIL 

       130        140        150        160        170        180 
EEVKDKNWGI VVISKSGTTL EPSVGFKLFR EALYKQYGEQ AQKRIVAITD PKKGVLHDIA 

       190        200        210        220        230        240 
VKNKYEMLPI YSDIGGRFST ITPSGLLVAG LVGADYKQLI EGAKKAKADL FASSELKKNS 

       250        260        270        280        290        300 
AYTYAALRHY LYTEMKKDVE IAITYEEQHE YLMLQHRQLF GESEGKSLNS LFPTYSVFTT 

       310        320        330        340        350        360 
DLHSMGQLYQ DGKKIFFETV FSFEKANKNK LKLKNSEFNN DDQLDYLTKK SVNQLNYVAC 

       370        380        390        400        410        420 
EATKQAHASA GVPIIEIDVK ENSAYGFGYL YFWLCVATSV SALLLGHDPY NQPGVENYKQ 


RMFKLL 

« Hide

References

« Hide 'large scale' references
[1]Skamrov A.V., Feoktistova E.S., Gol'dman M.A., Bibilashvili R.S.
Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: A5969Var.B.
[2]"The complete genome sequence of the avian pathogen Mycoplasma gallisepticum strain R(low)."
Papazisi L., Gorton T.S., Kutish G., Markham P.F., Browning G.F., Nguyen D.K., Swartzell S., Madan A., Mahairas G., Geary S.J.
Microbiology 149:2307-2316(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: R(low / passage 15 / clone 2).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L35043 Genomic DNA. Translation: AAF36765.1.
AE015450 Genomic DNA. Translation: AAP56986.2.
RefSeqNP_853418.2. NC_004829.2.

3D structure databases

ProteinModelPortalQ9KX58.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAP56986; AAP56986; MGA_0457.
GeneID1089949.
KEGGmga:MGA_0457.
PATRIC20009167. VBIMycGal115357_0713.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000100403.
KOK01810.
OMAEPSLHFV.
ProtClustDBPRK14097.

Enzyme and pathway databases

BioCycMGAL710127:GC09-718-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_MYCGA
AccessionPrimary (citable) accession number: Q9KX58
Entry history
Integrated into UniProtKB/Swiss-Prot: November 2, 2001
Last sequence update: August 15, 2003
Last modified: February 19, 2014
This is version 81 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways