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Q9KVZ7 (T2X1_XANVA) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Type-2 restriction enzyme XhoI

Short name=R.XhoI
EC=3.1.21.4
Alternative name(s):
Endonuclease XhoI
Type II restriction enzyme XhoI
OrganismXanthomonas vasicola
Taxonomic identifier56459 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas

Protein attributes

Sequence length248 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Recognizes the double-stranded sequence CTCGAG and cleaves after C-1.

Catalytic activity

Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.

Sequence similarities

Belongs to the type II restriction enzyme XhoI family.

Ontologies

Keywords
   Biological processRestriction system
   Molecular functionEndonuclease
Hydrolase
Nuclease
Gene Ontology (GO)
   Biological_processDNA restriction-modification system

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionDNA binding

Inferred from electronic annotation. Source: InterPro

Type II site-specific deoxyribonuclease activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 248248Type-2 restriction enzyme XhoI
PRO_0000077372

Sequences

Sequence LengthMass (Da)Tools
Q9KVZ7 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 81D3B2B231BE6622

FASTA24827,575
        10         20         30         40         50         60 
MALDLAEYDR LARLGVAQFW DGRSSALEND EERSQGGERS GVLGGRNMDG FLAMIEGIVR 

        70         80         90        100        110        120 
KNGLPDAEVC IKGRPNLTLP GYYRPTKLWD VLVFDGKKLV AAVELKSHVG PSFGNNFNNR 

       130        140        150        160        170        180 
AEEAIGTAHD LATAIREGIL GDQLPPFTGW LILVEDCEKS KRAVRDSSPH FPVFPDFKGA 

       190        200        210        220        230        240 
SYLTRYEVLC RKLILKGFTP RPQSLLRPAL RVLGATIASF RKPRVCAHLR HGWPAMYPVG 


QSRIRVNF 

« Hide

References

[1]"Nucleotide sequences of the XhoI methylase and endonuclease genes."
Morita M., Sugino Y.
Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 13461 / XH 3 / LMG 7416.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB046567 Genomic DNA. Translation: BAB03597.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Chemistry

ChEMBLCHEMBL2439945.

Protein family/group databases

REBASE2136. XhoI.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR007636. Restrct_endonuc_II_XhoI.
[Graphical view]
PfamPF04555. XhoI. 1 hit.
[Graphical view]
PIRSFPIRSF000994. Restrict_endonuc_II_XhoI. 1 hit.
ProtoNetSearch...

Entry information

Entry nameT2X1_XANVA
AccessionPrimary (citable) accession number: Q9KVZ7
Entry history
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 1, 2000
Last modified: June 11, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Restriction enzymes and methylases

Classification of restriction enzymes and methylases and list of entries