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Q9KVW8 (SYGB_VIBCH) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glycine--tRNA ligase beta subunit
EC=6.1.1.14
Alternative name(s):
Glycyl-tRNA synthetase beta subunit
Short name=GlyRS
Gene names
Name:glyS
Ordered Locus Names:VC_0020
OrganismVibrio cholerae
Taxonomic identifier666 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio

Protein attributes

Sequence length688 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP MF_00255

Subunit structure

Tetramer of two alpha and two beta subunits By similarity.

Subcellular location

Cytoplasm HAMAP MF_00255.

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: InterPro

glycyl-tRNA aminoacylation

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: InterPro

glycine-tRNA ligase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 688688Glycine--tRNA ligase beta subunit HAMAP MF_00255
PRO_0000072935

Sequences

Sequence LengthMass (Da)Tools
Q9KVW8 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 9B6A9A21715D2B39

FASTA68875,925
        10         20         30         40         50         60 
MAKEFLIELG TEELPPKQLR TLAEAFAANF AAELATADIA HEGVTWFATP RRLALKVANL 

        70         80         90        100        110        120 
AESQPDRVVE KRGPAVNVAF DADGKPTKAA EGWARGNGIT VEQAERLVTD KGEWLLFKEQ 

       130        140        150        160        170        180 
VQGQQTASVV VEMAAKALAN LPIAKPMRWG DKETQFIRPV KTLTILFGSE LIQGEILGVA 

       190        200        210        220        230        240 
SARTLRGHRF MGEAEFTIES AEQYPAILEE RGKVIADYAT RKAMIIEGSQ QAAQQLGGIA 

       250        260        270        280        290        300 
DLEDALVEEV TSLVEWPVVM TAKFEEKFLK VPAEALVYTM KGDQKYFPVY DASKKLLPNF 

       310        320        330        340        350        360 
IFVSNIESKE PRHIVEGNEK VVRPRLADAE FFFNTDRKRP LVDRLPLLEN AIFQQQLGTI 

       370        380        390        400        410        420 
KDKTDRITEL AGYIAEQIGA DVEKSKRAGL LAKCDLMTSM VFEFTDTQGV MGMHYARHDG 

       430        440        450        460        470        480 
EAEEVAVALN EQYMPRFAGD ELPSRGVSAA VAMADKLDTI VGIFGIGQAP KGSDPFALRR 

       490        500        510        520        530        540 
ASLGVLRILV EYGYQLDLVD LIAKAKSLFG DRLTNANVEQ EVIEFMLGRF PTWYQDAGFS 

       550        560        570        580        590        600 
IDIIQAVLAR NPTKPADFDQ RVKAVSHFRA LEEAEALAAA NKRVGNILAK YDGELGEEID 

       610        620        630        640        650        660 
LALLQEDAEK ALAEAVEIMA EALEPAFATG NYQEALSKLA GLRAPVDAFF DNVMVMADDE 

       670        680 
ALKKNRLTLL NKLRNLFLQI ADISLLQK

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE003852 Genomic DNA. Translation: AAF93198.1.
PIRF82373.
RefSeqNP_229679.1. NC_002505.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2614960.
GenomeReviewsGene locus VC_0020 in contig AE003852_GR.
KEGGvch:VC0020.
PATRIC20079088. VBIVibCho83274_0019.
TIGRVC_0020.

Phylogenomic databases

HOGENOMHBG586599.
OMAFIRPVHT.
PhylomeDBQ9KVW8.
ProtClustDBPRK01233.

Family and domain databases

HAMAPMF_00255. Gly_tRNA_synth_beta.
[Tree]
InterProIPR008909. DALR_anticod-bd.
IPR006194. Gly-tRNA-synth_II_heterodimer.
IPR015944. Gly-tRNA-synth_IIc_bsu.
IPR023279. HD.
[Graphical view]
Gene3DG3DSA:1.10.3210.10. HD. 1 hit.
KOK01879.
PfamPF05746. DALR_1. 1 hit.
PF02092. tRNA_synt_2f. 1 hit.
[Graphical view]
PRINTSPR01045. TRNASYNTHGB.
SMARTSM00836. DALR_1. 1 hit.
[Graphical view]
TIGRFAMsTIGR00211. GlyS. 1 hit.
PROSITEPS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYGB_VIBCH
AccessionPrimary (citable) accession number: Q9KVW8
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: October 1, 2000
Last modified: January 25, 2012
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries

SIMILARITY comments

Index of protein domains and families

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