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Q9KVL6 (DAPF_VIBCH) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Diaminopimelate epimerase
Short name=DAP epimerase
EC=5.1.1.7
Gene names
Name:dapF
Ordered Locus Names:VC_0126
OrganismVibrio cholerae
Taxonomic identifier666 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio

Protein attributes

Sequence length276 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

LL-2,6-diaminoheptanedioate = meso-diaminoheptanedioate. HAMAP MF_00197

Pathway

Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; DL-2,6-diaminopimelate from LL-2,6-diaminopimelate: step 1/1. HAMAP MF_00197

Subcellular location

Cytoplasm By similarity HAMAP MF_00197.

Sequence similarities

Belongs to the diaminopimelate epimerase family.

Sequence caution

The sequence AAF93303.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Lysine biosynthesis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processlysine biosynthetic process via diaminopimelate

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functiondiaminopimelate epimerase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 276276Diaminopimelate epimerase HAMAP MF_00197
PRO_0000149875

Sites

Active site751 By similarity
Active site2191 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9KVL6 [UniParc].

Last modified June 6, 2002. Version 2.
Checksum: 8FCFEC10E5DD714B

FASTA27630,651
        10         20         30         40         50         60 
MHFHFSKMHG LGNDFMVVDC ITQNVFFSPE LIRRLADRHT GVGFDQLLVV EAPYDPESDF 

        70         80         90        100        110        120 
HYRIFNADGS EVEQCGNGAR CFARFVRMKG LTNKYTIHVS TKKGKMVLNV EEEDLITVNM 

       130        140        150        160        170        180 
GVPEFEPNKI PFRAKQSEKT YILRVGEHTL FCGAVSMGNP HVVTVVDDIR TAAVETLGPL 

       190        200        210        220        230        240 
LESHERFPER VNAGFMQVVS RDEINLRVYE RGAGETQACG SGACAAVAVG ILQGLLDEQV 

       250        260        270 
RVHLPGGELE IHWQGPGKPL YMTGPATHIY DGQISC

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE003852 Genomic DNA. Translation: AAF93303.1. Different initiation.
PIRG82360.
RefSeqNP_229784.2. NC_002505.1.

3D structure databases

ProteinModelPortalQ9KVL6.
SMRQ9KVL6. Positions 4-275.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2614550.
GenomeReviewsGene locus VC_0126 in contig AE003852_GR.
KEGGvch:VC0126.
PATRIC20079296. VBIVibCho83274_0117.
TIGRVC_0126.

Phylogenomic databases

HOGENOMHBG399442.
OMAFMTGPAT.
PhylomeDBQ9KVL6.
ProtClustDBPRK00450.

Family and domain databases

HAMAPMF_00197. DAP_epimerase.
[Tree]
InterProIPR018510. DAP_epimerase_AS.
IPR001653. DAP_epimerase_DapF.
[Graphical view]
KOK01778.
PfamPF01678. DAP_epimerase. 2 hits.
[Graphical view]
TIGRFAMsTIGR00652. DapF. 1 hit.
PROSITEPS01326. DAP_EPIMERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDAPF_VIBCH
AccessionPrimary (citable) accession number: Q9KVL6
Entry history
Integrated into UniProtKB/Swiss-Prot: June 6, 2002
Last sequence update: June 6, 2002
Last modified: January 25, 2012
This is version 57 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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