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Protein

Protein translocase subunit SecE

Gene

secE

Organism
Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.UniRule annotation

GO - Molecular functioni

GO - Biological processi

  • protein secretion Source: TIGR
  • protein targeting Source: InterPro

Keywordsi

Biological processProtein transport, Translocation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Protein translocase subunit SecEUniRule annotation
Gene namesi
Name:secEUniRule annotation
Ordered Locus Names:VC_0322
OrganismiVibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Taxonomic identifieri243277 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
Proteomesi
  • UP000000584 Componenti: Chromosome 1

Subcellular locationi

  • Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei18 – 38HelicalUniRule annotationAdd BLAST21
Transmembranei40 – 60HelicalUniRule annotationAdd BLAST21
Transmembranei97 – 117HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001041931 – 126Protein translocase subunit SecEAdd BLAST126

Interactioni

Subunit structurei

Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.UniRule annotation

Protein-protein interaction databases

STRINGi243277.VC0322.

Family & Domainsi

Sequence similaritiesi

Belongs to the SecE/SEC61-gamma family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105PM1. Bacteria.
COG0690. LUCA.
KOiK03073.
OMAiFLWLTDK.

Family and domain databases

HAMAPiMF_00422. SecE. 1 hit.
InterProiView protein in InterPro
IPR022943. SecE.
IPR005807. SecE_bac.
IPR001901. Translocase_SecE/Sec61-g.
PfamiView protein in Pfam
PF00584. SecE. 1 hit.
PRINTSiPR01650. SECETRNLCASE.
TIGRFAMsiTIGR00964. secE_bact. 1 hit.
PROSITEiView protein in PROSITE
PS01067. SECE_SEC61G. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9KV36-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKANNAEAPD SSNAADTLKW VATFVLLVAA VVGNYLYGEL SVVARAAGVI
60 70 80 90 100
VLIAAALGVA ATTTKGKEAI VFARESRMEV RKVVWPTRQE TMQTTLIVLA
110 120
VSIVMALALW GIDGIMVRLV AFATGV
Length:126
Mass (Da):13,276
Last modified:June 20, 2001 - v2
Checksum:i8A9FFD4D3668EE47
GO

Sequence cautioni

The sequence AAF93495 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE003852 Genomic DNA. Translation: AAF93495.1. Different initiation.
PIRiH82337.
RefSeqiNP_229976.1. NC_002505.1.

Genome annotation databases

EnsemblBacteriaiAAF93495; AAF93495; VC_0322.
GeneIDi2615088.
KEGGivch:VC0322.
PATRICifig|243277.26.peg.299.

Similar proteinsi

Entry informationi

Entry nameiSECE_VIBCH
AccessioniPrimary (citable) accession number: Q9KV36
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 20, 2001
Last sequence update: June 20, 2001
Last modified: August 30, 2017
This is version 97 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families