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Q9KUZ6

- EFTU2_VIBCH

UniProt

Q9KUZ6 - EFTU2_VIBCH

Protein

Elongation factor Tu-B

Gene

tufB

Organism
Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 85 (01 Oct 2014)
      Sequence version 1 (01 Oct 2000)
      Previous versions | rss
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    Functioni

    This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi19 – 268GTPUniRule annotation
    Nucleotide bindingi81 – 855GTPUniRule annotation
    Nucleotide bindingi136 – 1394GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: InterPro
    2. GTP binding Source: UniProtKB-HAMAP
    3. translation elongation factor activity Source: TIGR

    GO - Biological processi

    1. translational elongation Source: TIGR

    Keywords - Molecular functioni

    Elongation factor

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciVCHO:VC0362-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor Tu-BUniRule annotation
    Short name:
    EF-Tu-BUniRule annotation
    Gene namesi
    Name:tufBUniRule annotation
    Ordered Locus Names:VC_0362
    OrganismiVibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
    Taxonomic identifieri243277 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
    ProteomesiUP000000584: Chromosome 1

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 394394Elongation factor Tu-BPRO_0000091432Add
    BLAST

    Proteomic databases

    PRIDEiQ9KUZ6.

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi243277.VC0362.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9KUZ6.
    SMRiQ9KUZ6. Positions 4-394.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini10 – 204195tr-type GAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni19 – 268G1By similarity
    Regioni60 – 645G2By similarity
    Regioni81 – 844G3By similarity
    Regioni136 – 1394G4By similarity
    Regioni174 – 1763G5By similarity

    Sequence similaritiesi

    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

    Phylogenomic databases

    KOiK02358.
    OMAiGTEMCMP.
    OrthoDBiEOG6R5C6X.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00118_B. EF_Tu_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. G_TR_1. 1 hit.
    PS51722. G_TR_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9KUZ6-1 [UniParc]FASTAAdd to Basket

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    MSKEKFERTK PHVNVGTIGH VDHGKTTLTA AICTVLAKVY GGKARDFASI    50
    DNAPEERERG ITINTSHVEY DTPNRHYAHV DCPGHADYVK NMITGAAQMD 100
    GGILVVAATD GPMPQTREHI LLGRQVGIPY IIVFMNKCDM VDDEELLELV 150
    EMEVRELLSE YDFPGDDLPV IQGSALGALN GEAQWEAKIV ELAEALDTYI 200
    PEPERAVDMA FLMPIEDVFS IQGRGTVVTG RIERGILKVG DEVAIVGIKE 250
    TVKTTCTGVE MFRKLLDEGR AGENVGALLR GTKREEVERG QVLAKPGSIT 300
    PHTKFESEVY VLSKDEGGRH TPFFKGYRPQ FYFRTTDVTG SIELPEGVEM 350
    VMPGDNVKMV VDLIAPIAMD EGLRFAIREG GRTVGAGVVA KIIA 394
    Length:394
    Mass (Da):43,126
    Last modified:October 1, 2000 - v1
    Checksum:iBF0DE31A00618B36
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE003852 Genomic DNA. Translation: AAF93535.1.
    PIRiD82332.
    RefSeqiNP_230016.1. NC_002505.1.

    Genome annotation databases

    EnsemblBacteriaiAAF93535; AAF93535; VC_0362.
    GeneIDi2615041.
    KEGGivch:VC0362.
    PATRICi20079797. VBIVibCho83274_0339.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE003852 Genomic DNA. Translation: AAF93535.1 .
    PIRi D82332.
    RefSeqi NP_230016.1. NC_002505.1.

    3D structure databases

    ProteinModelPortali Q9KUZ6.
    SMRi Q9KUZ6. Positions 4-394.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 243277.VC0362.

    Proteomic databases

    PRIDEi Q9KUZ6.

    Protocols and materials databases

    DNASUi 2615041.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAF93535 ; AAF93535 ; VC_0362 .
    GeneIDi 2615041.
    KEGGi vch:VC0362.
    PATRICi 20079797. VBIVibCho83274_0339.

    Phylogenomic databases

    KOi K02358.
    OMAi GTEMCMP.
    OrthoDBi EOG6R5C6X.

    Enzyme and pathway databases

    BioCyci VCHO:VC0362-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00118_B. EF_Tu_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. G_TR_1. 1 hit.
    PS51722. G_TR_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 39315 / El Tor Inaba N16961.

    Entry informationi

    Entry nameiEFTU2_VIBCH
    AccessioniPrimary (citable) accession number: Q9KUZ6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 19, 2002
    Last sequence update: October 1, 2000
    Last modified: October 1, 2014
    This is version 85 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3