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Q9KUY4

- G6PI_VIBCH

UniProt

Q9KUY4 - G6PI_VIBCH

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Protein

Glucose-6-phosphate isomerase

Gene
pgi, VC_0374
Organism
Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei356 – 3561Proton donor By similarity
Active sitei387 – 3871 By similarity
Active sitei515 – 5151 By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: TIGR

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: TIGR
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciVCHO:VC0374-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:VC_0374
OrganismiVibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Taxonomic identifieri243277 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
ProteomesiUP000000584: Chromosome 1

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 550550Glucose-6-phosphate isomeraseUniRule annotationPRO_0000180762Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi243277.VC0374.

Structurei

Secondary structure

1
550
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi7 – 93
Helixi11 – 2313
Helixi28 – 336
Helixi38 – 414
Beta strandi43 – 464
Turni47 – 493
Beta strandi50 – 534
Beta strandi56 – 583
Helixi61 – 7313
Helixi76 – 8510
Turni91 – 944
Helixi99 – 1024
Beta strandi115 – 1173
Helixi118 – 13720
Beta strandi150 – 1545
Helixi157 – 1593
Helixi161 – 1699
Helixi171 – 1733
Beta strandi178 – 1825
Helixi187 – 1948
Helixi199 – 2013
Beta strandi202 – 2076
Beta strandi209 – 2113
Helixi214 – 23118
Helixi234 – 2396
Beta strandi241 – 2466
Helixi248 – 2547
Helixi258 – 2603
Helixi270 – 2723
Turni274 – 2763
Helixi277 – 2793
Helixi280 – 2867
Helixi288 – 30720
Helixi310 – 3123
Helixi314 – 32714
Beta strandi333 – 3397
Helixi341 – 3433
Helixi346 – 35813
Beta strandi376 – 3783
Turni382 – 3854
Helixi386 – 39510
Beta strandi396 – 3983
Beta strandi402 – 4098
Helixi417 – 43418
Helixi438 – 44710
Helixi452 – 46211
Beta strandi470 – 4767
Helixi480 – 50021
Helixi509 – 5113
Helixi512 – 52110
Helixi522 – 5254
Beta strandi526 – 5283
Helixi536 – 54914

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3HJBX-ray1.50A/B/C/D1-550[»]
ProteinModelPortaliQ9KUY4.
SMRiQ9KUY4. Positions 8-549.

Miscellaneous databases

EvolutionaryTraceiQ9KUY4.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.

Phylogenomic databases

eggNOGiCOG0166.
KOiK01810.
OMAiNCHFVAN.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9KUY4-1 [UniParc]FASTAAdd to Basket

« Hide

MLKNINPTQT QAWKALTAHF ESAQDMDLKA LFAQDSERFA KYSARFGQDI    50
LVDYSKNLVN AETMQHLFAL AKETDLQSAI TAMFKGEAIN QTEDRAVLHT 100
ALRNRSNSPV LVNGEDVMPA VNAVLAKMKA FSERVIGGEW KGFTGKAITD 150
VVNIGIGGSD LGPYMVTEAL VPYKNHLTMH FVSNVDGTHM AETLKNVDPE 200
TTLFLVASKT FTTQETMTNA HTARDWFLKA AGDEAHVAKH FAALSTNGKA 250
VAEFGIDTDN MFEFWDWVGG RYSLWSAIGL SIILSIGYDN FVELLAGAHE 300
MDQHFVNTPF ESNIPVILAL IGIWYNNFHG AESEAILPYD QYLHRFAAYF 350
QQGNMESNGK YVDRNGNPVT YQTGPIIWGE PGTNGQHAFY QLIHQGTKLI 400
PCDFIAPAVS HNLVGDHHQK LMSNFFAQTE ALAFGKSAQA VQAELEKAGK 450
SAAEIAALVP FKVFEGNRPT NSILVKQITP RTLGNLIAMY EHKIFVQGVI 500
WNIFSFDQWG VELGKQLANQ ILPELADSAA VTSHDSSTNG LINAFKAFRA 550
Length:550
Mass (Da):60,691
Last modified:October 1, 2000 - v1
Checksum:i5E38B0421C3A1B16
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE003852 Genomic DNA. Translation: AAF93547.1.
PIRiB82330.
RefSeqiNP_230028.1. NC_002505.1.

Genome annotation databases

EnsemblBacteriaiAAF93547; AAF93547; VC_0374.
GeneIDi2615017.
KEGGivch:VC0374.
PATRICi20079819. VBIVibCho83274_0350.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE003852 Genomic DNA. Translation: AAF93547.1 .
PIRi B82330.
RefSeqi NP_230028.1. NC_002505.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3HJB X-ray 1.50 A/B/C/D 1-550 [» ]
ProteinModelPortali Q9KUY4.
SMRi Q9KUY4. Positions 8-549.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243277.VC0374.

Protocols and materials databases

DNASUi 2615017.
Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAF93547 ; AAF93547 ; VC_0374 .
GeneIDi 2615017.
KEGGi vch:VC0374.
PATRICi 20079819. VBIVibCho83274_0350.

Phylogenomic databases

eggNOGi COG0166.
KOi K01810.
OMAi NCHFVAN.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
BioCyci VCHO:VC0374-MONOMER.

Miscellaneous databases

EvolutionaryTracei Q9KUY4.

Family and domain databases

Gene3Di 1.10.1390.10. 1 hit.
HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 39315 / El Tor Inaba N16961.

Entry informationi

Entry nameiG6PI_VIBCH
AccessioniPrimary (citable) accession number: Q9KUY4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 2, 2001
Last sequence update: October 1, 2000
Last modified: June 11, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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