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Q9KUX2 (CYSH_VIBCH) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoadenosine phosphosulfate reductase
EC=1.8.4.8
Alternative name(s):
3'-phosphoadenylylsulfate reductase
PAPS reductase, thioredoxin dependent
PAPS sulfotransferase
PAdoPS reductase
Gene names
Name:cysH
Ordered Locus Names:VC_0386
OrganismVibrio cholerae
Taxonomic identifier666 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio

Protein attributes

Sequence length253 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Reduction of activated sulfate into sulfite. HAMAP MF_00063

Catalytic activity

Adenosine 3',5'-bisphosphate + sulfite + thioredoxin disulfide = 3'-phosphoadenylyl sulfate + thioredoxin. HAMAP MF_00063

Pathway

Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 3/3. HAMAP MF_00063

Subcellular location

Cytoplasm By similarity HAMAP MF_00063.

Sequence similarities

Belongs to the PAPS reductase family. CysH subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 253253Phosphoadenosine phosphosulfate reductase HAMAP MF_00063
PRO_0000100652

Sequences

Sequence LengthMass (Da)Tools
Q9KUX2 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: A92EF4BEE08A9FFD

FASTA25329,249
        10         20         30         40         50         60 
MPNRTVPTLE ELLTLNKVQQ TLRLTEVNQH LESLTAQERV VWGLENLQGN HALSSSFGIQ 

        70         80         90        100        110        120 
AAVMLHLLTS VKSDIPVVLT DTGYLFPETY QFIDELTERL NLNLKVYSAP VSAAWQEARY 

       130        140        150        160        170        180 
GKLWEQGVEG IERYNQINKV EPMRRALDEL NIGTWFSGLR REQSQSRASL PILSVQNGVF 

       190        200        210        220        230        240 
KFLPVIDWTN KEVHYYLKDN DLPYHPLWEQ GYLSVGDTHT TQKWQPGMNE EQTRFFGLKR 

       250 
ECGLHEDHND THQ

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE003852 Genomic DNA. Translation: AAF93559.1.
PIRD82329.
RefSeqNP_230040.1. NC_002505.1.

3D structure databases

ProteinModelPortalQ9KUX2.
SMRQ9KUX2. Positions 9-246.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2615029.
GenomeReviewsGene locus VC_0386 in contig AE003852_GR.
KEGGvch:VC0386.
PATRIC20079843. VBIVibCho83274_0362.
TIGRVC_0386.

Phylogenomic databases

HOGENOMHBG758022.
OMAAIHGTRF.
PhylomeDBQ9KUX2.
ProtClustDBPRK02090.

Family and domain databases

HAMAPMF_00063. CysH.
[Tree]
InterProIPR004511. PAPS/APS_Rdtase.
IPR002500. PAPS_reduct.
IPR011800. PAPS_reductase_CysH.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
Gene3DG3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
KOK00390.
PfamPF01507. PAPS_reduct. 1 hit.
[Graphical view]
TIGRFAMsTIGR00434. CysH. 1 hit.
TIGR02057. PAPS_reductase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameCYSH_VIBCH
AccessionPrimary (citable) accession number: Q9KUX2
Entry history
Integrated into UniProtKB/Swiss-Prot: July 11, 2002
Last sequence update: October 1, 2000
Last modified: January 25, 2012
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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