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Q9KUR1

- GLSA_VIBCH

UniProt

Q9KUR1 - GLSA_VIBCH

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Protein
Glutaminase
Gene
glsA, VC_0454
Organism
Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei64 – 641Substrate By similarity
Binding sitei115 – 1151Substrate By similarity
Binding sitei159 – 1591Substrate By similarity
Binding sitei166 – 1661Substrate By similarity
Binding sitei190 – 1901Substrate By similarity
Binding sitei242 – 2421Substrate By similarity
Binding sitei260 – 2601Substrate; via amide nitrogen By similarity

GO - Molecular functioni

  1. catalytic activity Source: TIGR
  2. glutaminase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. glutamine metabolic process Source: InterPro
  2. metabolic process Source: TIGR
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Glutaminase (EC:3.5.1.2)
Gene namesi
Name:glsA
Ordered Locus Names:VC_0454
OrganismiVibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Taxonomic identifieri243277 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
ProteomesiUP000000584: Chromosome 1

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 306306GlutaminaseUniRule annotation
PRO_0000110629Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi243277.VC0454.

Structurei

3D structure databases

ProteinModelPortaliQ9KUR1.

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.

Phylogenomic databases

eggNOGiCOG2066.
KOiK01425.
OMAiMSIAVWS.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9KUR1-1 [UniParc]FASTAAdd to Basket

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MKPTADILAS IIEEVRPLTS KGIVADYIPA LAKVPSDKLG IAVFTNQGEV    50
ITAGDAQEGF SIQSISKVLS LTLAMGLYQP DELWSRVGKE PSGQAFNSLI 100
QLEMEQGIPR NPFINAGAIV VCDMLQSRLS APRQRLLEFV RQLSGEPQIA 150
YDKVVAASEM MHSDRNAAIA YLMRSFGNFH NEVIPVLHNY FHACALKMSC 200
VELAKTFSYL ANKGVSVVTG ETVITPTQSK QTNALLATCG LYDGAGEFAY 250
RVGMPGKSGV GGGIIAVVPG EMTIAVWSPA LDQSGNSLAG TRALELLAQR 300
IGRSIF 306
Length:306
Mass (Da):32,765
Last modified:June 16, 2003 - v2
Checksum:i24FAE9E570A002B3
GO

Sequence cautioni

The sequence AAF93627.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE003852 Genomic DNA. Translation: AAF93627.1. Different initiation.
PIRiF82320.
RefSeqiNP_230108.1. NC_002505.1.

Genome annotation databases

EnsemblBacteriaiAAF93627; AAF93627; VC_0454.
GeneIDi2615116.
KEGGivch:VC0454.
PATRICi20080003. VBIVibCho83274_0427.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE003852 Genomic DNA. Translation: AAF93627.1 . Different initiation.
PIRi F82320.
RefSeqi NP_230108.1. NC_002505.1.

3D structure databases

ProteinModelPortali Q9KUR1.
ModBasei Search...

Protein-protein interaction databases

STRINGi 243277.VC0454.

Protocols and materials databases

DNASUi 2615116.
Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAF93627 ; AAF93627 ; VC_0454 .
GeneIDi 2615116.
KEGGi vch:VC0454.
PATRICi 20080003. VBIVibCho83274_0427.

Phylogenomic databases

eggNOGi COG2066.
KOi K01425.
OMAi MSIAVWS.
OrthoDBi EOG6N94BK.

Family and domain databases

Gene3Di 3.40.710.10. 1 hit.
HAMAPi MF_00313. Glutaminase.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view ]
PANTHERi PTHR12544. PTHR12544. 1 hit.
Pfami PF04960. Glutaminase. 1 hit.
[Graphical view ]
SUPFAMi SSF56601. SSF56601. 1 hit.
TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 39315 / El Tor Inaba N16961.

Entry informationi

Entry nameiGLSA_VIBCH
AccessioniPrimary (citable) accession number: Q9KUR1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 24, 2001
Last sequence update: June 16, 2003
Last modified: May 14, 2014
This is version 73 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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