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Q9KUJ4 (UPPP_VIBCH) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Synonyms:bacA, upk
Ordered Locus Names:VC_0526
OrganismVibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) [Reference proteome] [HAMAP]
Taxonomic identifier243277 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio

Protein attributes

Sequence length267 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 267267Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_0000151234

Regions

Transmembrane1 – 2121Helical; Potential
Transmembrane39 – 5921Helical; Potential
Transmembrane83 – 10321Helical; Potential
Transmembrane111 – 13121Helical; Potential
Transmembrane149 – 16921Helical; Potential
Transmembrane189 – 20921Helical; Potential
Transmembrane218 – 23821Helical; Potential
Transmembrane245 – 26521Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q9KUJ4 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 1A02C60BF0951D9A

FASTA26729,285
        10         20         30         40         50         60 
MSYFESFILA LIQGFTEFLP ISSSAHLILP SAILGWEDQG LAFDVAVHVG TLAAVVLYFR 

        70         80         90        100        110        120 
KEVVSLLSAF FASIFKGDRS KEAKLAWLIV LATIPACLFG FVMKDIVELY LRSAWVIATT 

       130        140        150        160        170        180 
TIVFGLLLWY VDKHAELKAD EYQADWKKAL FIGLAQAVAI IPGTSRSGAT ITAALYLGFT 

       190        200        210        220        230        240 
REAAARFSFL MSIPIIVLAG SYLGLKLVTS GEPVHSGFLL TGIITSFISA YICIHFFLKL 

       250        260 
ISRMGMTPFV IYRLVLGVGL FAFLLTQ 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE003852 Genomic DNA. Translation: AAF93694.1.
PIRE82313.
RefSeqNP_230177.1. NC_002505.1.

3D structure databases

ProteinModelPortalQ9KUJ4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243277.VC0526.

Protocols and materials databases

DNASU2615817.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAF93694; AAF93694; VC_0526.
GeneID2615817.
KEGGvch:VC0526.
PATRIC20080156. VBIVibCho83274_0502.

Phylogenomic databases

eggNOGCOG1968.
KOK06153.
OMAMGASKRS.
OrthoDBEOG6QP13M.
ProtClustDBPRK00281.

Enzyme and pathway databases

BioCycVCHO:VC0526-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP_VIBCH
AccessionPrimary (citable) accession number: Q9KUJ4
Entry history
Integrated into UniProtKB/Swiss-Prot: March 5, 2002
Last sequence update: October 1, 2000
Last modified: February 19, 2014
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families