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Q9KU37 (NAGZ_VIBCH) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Beta-hexosaminidase
EC=3.2.1.52
Alternative name(s):
Beta-N-acetylhexosaminidase
N-acetyl-beta-glucosaminidase
Gene names
Name:nagZ
Ordered Locus Names:VC_0692
OrganismVibrio cholerae
Taxonomic identifier666 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio

Protein attributes

Sequence length330 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides By similarity. HAMAP MF_00364

Catalytic activity

Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides. HAMAP MF_00364

Pathway

Cell wall biogenesis; peptidoglycan recycling. HAMAP MF_00364

Subunit structure

Monomer Potential.

Subcellular location

Cytoplasm By similarity HAMAP MF_00364.

Sequence similarities

Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 330330Beta-hexosaminidase HAMAP MF_00364
PRO_0000210800

Sites

Active site2421 By similarity

Secondary structure

1 .......................................................... 330
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q9KU37 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: A737BD82C149D3A2

FASTA33036,466
        10         20         30         40         50         60 
MGPLWLDVAG YELSAEDREI LQHPTVGGVI LFGRNYHDNQ QLLALNKAIR QAAKRPILIG 

        70         80         90        100        110        120 
VDQEGGRVQR FREGFSRIPP AQYYARAENG VELAEQGGWL MAAELIAHDV DLSFAPVLDM 

       130        140        150        160        170        180 
GFACKAIGNR AFGEDVQTVL KHSSAFLRGM KAVGMATTGK HFPGHGAVIA DSHLETPYDE 

       190        200        210        220        230        240 
RETIAQDMAI FRAQIEAGVL DAMMPAHVVY PHYDAQPASG SSYWLKQVLR EELGFKGIVF 

       250        260        270        280        290        300 
SDDLSMEGAA VMGGPVERSH QALVAGCDMI LICNKREAAV EVLDNLPIME VPQAEALLKK 

       310        320        330 
QQFSYSELKR LERWQQASAN MQRLIEQFSE

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE003852 Genomic DNA. Translation: AAF93857.1.
PIRA82292.
RefSeqNP_230341.1. NC_002505.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1TR9X-ray1.80A2-330[»]
1Y65X-ray1.85A2-330[»]
2OXNX-ray1.70A1-330[»]
3GS6X-ray2.30A1-330[»]
3GSMX-ray2.40A1-330[»]
ProteinModelPortalQ9KU37.
SMRQ9KU37. Positions 1-330.
ModBaseSearch...

Protein family/group databases

CAZyGH3. Glycoside Hydrolase Family 3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2615481.
GenomeReviewsGene locus VC_0692 in contig AE003852_GR.
KEGGvch:VC0692.
PATRIC20080499. VBIVibCho83274_0663.
TIGRVC_0692.

Phylogenomic databases

HOGENOMHBG617255.
OMADLTMEGA.
PhylomeDBQ9KU37.
ProtClustDBPRK05337.

Family and domain databases

HAMAPMF_00364. NagZ.
[Tree]
InterProIPR022956. Beta_hexosaminidase.
IPR019800. Glyco_hydro_3_AS.
IPR001764. Glyco_hydro_3_N.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
Gene3DG3DSA:3.20.20.300. Glyco_hydro_3_N. 1 hit.
KOK01207.
PfamPF00933. Glyco_hydro_3. 1 hit.
[Graphical view]
SUPFAMSSF51445. Glyco_hydro_cat. 1 hit.
PROSITEPS00775. GLYCOSYL_HYDROL_F3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameNAGZ_VIBCH
AccessionPrimary (citable) accession number: Q9KU37
Entry history
Integrated into UniProtKB/Swiss-Prot: May 4, 2001
Last sequence update: October 1, 2000
Last modified: January 25, 2012
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries

PATHWAY comments

Index of metabolic and biosynthesis pathways

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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