Q9KTY5 (SUHB_VIBCH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Inositol-1-monophosphatase
Short name=I-1-Pase
Short name=IMPase
Short name=Inositol-1-phosphatase
EC=3.1.3.25

Gene names

Ordered Locus Names:

VC_0745

Organism

Vibrio cholerae

Taxonomic identifier

666 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio

Protein attributes

Sequence length	267 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Myo-inositol phosphate + H2O = myo-inositol + phosphate.
Cofactor	Magnesium By similarity.
Sequence similarities	Belongs to the inositol monophosphatase family.
Sequence caution	The sequence AAF93910.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	inositol monophosphate 1-phosphatase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 267	267	Inositol-1-monophosphatase		PRO_0000142575
Regions
	Region	86 – 89	4	Substrate binding By similarity
Sites
	Metal binding	67	1	Magnesium 1 By similarity
	Metal binding	84	1	Magnesium 1 By similarity
	Metal binding	84	1	Magnesium 2 By similarity
	Metal binding	86	1	Magnesium 1; via carbonyl oxygen By similarity
	Metal binding	87	1	Magnesium 2 By similarity
	Metal binding	212	1	Magnesium 2 By similarity
	Binding site	67	1	Substrate By similarity
	Binding site	183	1	Substrate By similarity
	Binding site	212	1	Substrate By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9KTY5 [UniParc]. Last modified January 23, 2002. Version 2. Checksum: 88AD8CDF78A7AD87	FASTA	267	29,088
	10 20 30 40 50 60 MHPMLNIAIR AARKAGNHIA KSLENAEKIQ TTQKGSNDFV TNVDKEAEAI IVSTIKSSYP 70 80 90 100 110 120 EHCIIAEEGG LIEGKDKEVQ WIIDPLDGTT NFVKGFPHFA VSIAVRFRGK TEVACVYDPM 130 140 150 160 170 180 TNELFTAQRG AGAQLNNARI RVQPIKDLQG AVLATAFPFK QKQHSESFMK ILSAMFVECA 190 200 210 220 230 240 DFRRTGSAAL DLCYLAANRV DGYFELGLKP WDMAAGELIA REAGAIVTDF AGGTDYMQSG 250 260 NIVASSPRGV KAILQHIREN GNSAILK

References

[1]

"DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae." Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L., Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R., Nelson K.E., Read T.D., Tettelin H., Richardson D.L., Ermolaeva M.D., Vamathevan J.J., Bass S. , Qin H., Dragoi I., Sellers P., McDonald L.A., Utterback T.R., Fleischmann R.D., Nierman W.C., White O., Salzberg S.L., Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M. Nature 406:477-483(2000) [PubMed: 10952301] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 39315 / El Tor Inaba N16961 / Serotype O1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE003852 Genomic DNA. Translation: AAF93910.1. Different initiation.
PIR	D82285.
RefSeq	NP_230394.1. NC_002505.1.
3D structure databases
ProteinModelPortal	Q9KTY5.
SMR	Q9KTY5. Positions 1-259.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2615754.
GenomeReviews	Gene locus VC_0745 in contig AE003852_GR.
KEGG	vch:VC0745.
PATRIC	20080601. VBIVibCho83274_0709.
TIGR	VC_0745.
Phylogenomic databases
HOGENOM	HBG730251.
OMA	TGFPFKQ.
PhylomeDB	Q9KTY5.
ProtClustDB	CLSK874093.
Family and domain databases
InterPro	IPR020583. Inositol_monoP_metal-BS. IPR000760. Inositol_monophosphatase. IPR020550. Inositol_monophosphatase_CS. IPR022337. Inositol_monophosphatase_SuhB. [Graphical view]
KO	K01092.
PANTHER	PTHR20854. Inositol_P. 1 hit.
Pfam	PF00459. Inositol_P. 1 hit. [Graphical view]
PRINTS	PR00377. IMPHPHTASES. PR01959. SBIMPHPHTASE.
PROSITE	PS00629. IMP_1. 1 hit. PS00630. IMP_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SUHB_VIBCH

Accession

Primary (citable) accession number: Q9KTY5

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 23, 2002
Last sequence update:	January 23, 2002
Last modified:	January 25, 2012
This is version 60 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program