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Protein

Co-chaperone protein HscB homolog

Gene

hscB

Organism
Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.UniRule annotation

GO - Molecular functioni

GO - Biological processi

  • iron-sulfur cluster assembly Source: GO_Central
  • protein folding Source: TIGR
  • protein oligomerization Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Enzyme and pathway databases

BioCyciVCHO:VC0751-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Co-chaperone protein HscB homologUniRule annotation
Gene namesi
Name:hscBUniRule annotation
Ordered Locus Names:VC_0751
OrganismiVibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Taxonomic identifieri243277 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
Proteomesi
  • UP000000584 Componenti: Chromosome 1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000709921 – 171Co-chaperone protein HscB homologAdd BLAST171

Interactioni

Subunit structurei

Interacts with HscA and stimulates its ATPase activity.UniRule annotation

GO - Molecular functioni

Protein-protein interaction databases

STRINGi243277.VC0751.

Structurei

Secondary structure

1171
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi3 – 6Combined sources4
Beta strandi11 – 13Combined sources3
Helixi17 – 30Combined sources14
Helixi33 – 36Combined sources4
Helixi41 – 62Combined sources22
Helixi64 – 73Combined sources10
Turni74 – 76Combined sources3
Turni81 – 86Combined sources6
Helixi89 – 104Combined sources16
Helixi105 – 107Combined sources3
Beta strandi108 – 110Combined sources3
Helixi111 – 138Combined sources28
Helixi142 – 169Combined sources28

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4IT5X-ray2.15A/B/C/D1-171[»]
ProteinModelPortaliQ9KTX9.
SMRiQ9KTX9.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9KTX9.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 74JUniRule annotationAdd BLAST73

Sequence similaritiesi

Belongs to the HscB family.UniRule annotation
Contains 1 J domain.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108SWN. Bacteria.
COG1076. LUCA.
KOiK04082.
OMAiDIRGEQQ.

Family and domain databases

CDDicd06257. DnaJ. 1 hit.
Gene3Di1.10.287.110. 1 hit.
1.20.1280.20. 1 hit.
HAMAPiMF_00682. HscB. 1 hit.
InterProiIPR001623. DnaJ_domain.
IPR004640. HscB.
IPR009073. HscB_oligo_C.
[Graphical view]
PANTHERiPTHR14021. PTHR14021. 1 hit.
PfamiPF00226. DnaJ. 1 hit.
PF07743. HSCB_C. 1 hit.
[Graphical view]
SMARTiSM00271. DnaJ. 1 hit.
[Graphical view]
SUPFAMiSSF46565. SSF46565. 1 hit.
SSF47144. SSF47144. 1 hit.
TIGRFAMsiTIGR00714. hscB. 1 hit.
PROSITEiPS50076. DNAJ_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9KTX9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNYFELFGLP IQFELDGSLL SSQFRALQKR FHPDNFATAS ERDRLMAVQQ
60 70 80 90 100
AAQINDAYQT LKDPLRRAEY LLSLQGIEMN AEQQTLQDPM FLMEQMELRE
110 120 130 140 150
ELESVTACAD PEAALVAFDT KVTAMQRHYL AQLQGQLAQS EWLAAADQIR
160 170
KLKFIAKLKN EVERVEDQLL G
Length:171
Mass (Da):19,627
Last modified:October 1, 2000 - v1
Checksum:i4516C70B3B51AF29
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE003852 Genomic DNA. Translation: AAF93916.1.
PIRiB82286.
RefSeqiNP_230400.1. NC_002505.1.
WP_001105747.1. NC_002505.1.

Genome annotation databases

EnsemblBacteriaiAAF93916; AAF93916; VC_0751.
GeneIDi2615760.
KEGGivch:VC0751.
PATRICi20080613. VBIVibCho83274_0715.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE003852 Genomic DNA. Translation: AAF93916.1.
PIRiB82286.
RefSeqiNP_230400.1. NC_002505.1.
WP_001105747.1. NC_002505.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4IT5X-ray2.15A/B/C/D1-171[»]
ProteinModelPortaliQ9KTX9.
SMRiQ9KTX9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243277.VC0751.

Protocols and materials databases

DNASUi2615760.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAF93916; AAF93916; VC_0751.
GeneIDi2615760.
KEGGivch:VC0751.
PATRICi20080613. VBIVibCho83274_0715.

Phylogenomic databases

eggNOGiENOG4108SWN. Bacteria.
COG1076. LUCA.
KOiK04082.
OMAiDIRGEQQ.

Enzyme and pathway databases

BioCyciVCHO:VC0751-MONOMER.

Miscellaneous databases

EvolutionaryTraceiQ9KTX9.

Family and domain databases

CDDicd06257. DnaJ. 1 hit.
Gene3Di1.10.287.110. 1 hit.
1.20.1280.20. 1 hit.
HAMAPiMF_00682. HscB. 1 hit.
InterProiIPR001623. DnaJ_domain.
IPR004640. HscB.
IPR009073. HscB_oligo_C.
[Graphical view]
PANTHERiPTHR14021. PTHR14021. 1 hit.
PfamiPF00226. DnaJ. 1 hit.
PF07743. HSCB_C. 1 hit.
[Graphical view]
SMARTiSM00271. DnaJ. 1 hit.
[Graphical view]
SUPFAMiSSF46565. SSF46565. 1 hit.
SSF47144. SSF47144. 1 hit.
TIGRFAMsiTIGR00714. hscB. 1 hit.
PROSITEiPS50076. DNAJ_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiHSCB_VIBCH
AccessioniPrimary (citable) accession number: Q9KTX9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 19, 2003
Last sequence update: October 1, 2000
Last modified: November 2, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.