Q9KTW3 (Q9KTW3_VIBCH) Unreviewed, UniProtKB/TrEMBL
Last modified
December 14, 2011.
Version 69.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize orderNames and origin
| Protein names | Recommended name: Inosine-5'-monophosphate dehydrogenase RuleBase RU003928 EC=1.1.1.205 RuleBase RU003928 | ||
| Gene names |
| ||
| Organism | Vibrio cholerae | ||
| Taxonomic identifier | 666 [NCBI] | ||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio |
Protein attributes
| Sequence length | 489 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Catalytic activity | Inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH. RuleBase RU003928 |
| Pathway | Purine metabolism; XMP biosynthesis via de novo pathway; XMP from IMP: step 1/1. RuleBase RU003928 |
| Sequence similarities | Belongs to the IMPDH/GMPR family. RuleBase RU003927 |
Ontologies
| Keywords | |
|---|---|
| Biological process | GMP biosynthesis RuleBase RU003928 Purine biosynthesis |
| Ligand | Metal-binding RuleBase RU003928 NAD RuleBase RU003928 Potassium RuleBase RU003928 |
| Molecular function | Oxidoreductase SAAS SAAS001093 RuleBase RU003927 |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological process | GMP biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | IMP dehydrogenase activity Inferred from electronic annotation. Source: EC metal ion bindingInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Sites | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Active site | 307 | 1 | Thioimidate intermediate By similarity PIRSR PIRSR000130-1 | ||||||
Sequences
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References
| [1] | "DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae." Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L., Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R., Nelson K.E., Read T.D., Tettelin H., Richardson D.L., Ermolaeva M.D., Vamathevan J.J., Bass S. Fraser C.M.Nature 406:477-483(2000) [PubMed: 10952301] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 39315 / El Tor Inaba N16961 / Serotype O1. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AE003852 Genomic DNA. Translation: AAF93932.1. |
| PIR | C82282. |
| RefSeq | NP_230416.1. NC_002505.1. |
3D structure databases | |
| HSSP | HSSP built from PDB template 1EEP based on UniProtKB P49058. |
| ProteinModelPortal | Q9KTW3. |
| SMR | Q9KTW3. Positions 5-487. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 2615310. |
| GenomeReviews | Gene locus VC_0767 in contig AE003852_GR. |
| KEGG | vch:VC0767. |
| PATRIC | 20080645. VBIVibCho83274_0731. |
| TIGR | VC_0767. |
Phylogenomic databases | |
| HOGENOM | HBG298985. |
| OMA | GIGIVHK. |
| PhylomeDB | Q9KTW3. |
| ProtClustDB | PRK05567. |
Family and domain databases | |
| InterPro | IPR013785. Aldolase_TIM. IPR000644. Cysta_beta_synth_core. IPR005990. IMP_DH. IPR018529. IMP_DH-rel. IPR015875. IMP_DH/GMP_Rdtase_CS. IPR001093. IMP_DH_GMPRt. [Graphical view] |
| Gene3D | G3DSA:3.20.20.70. Aldolase_TIM. 1 hit. |
| KO | K00088. |
| PANTHER | PTHR11911:SF6. IMP_DH_GMPRtase. 1 hit. |
| Pfam | PF00571. CBS. 2 hits. PF00478. IMPDH. 1 hit. [Graphical view] |
| PIRSF | PIRSF000130. IMPDH. 1 hit. |
| SMART | SM00116. CBS. 2 hits. [Graphical view] |
| TIGRFAMs | TIGR01302. IMP_dehydrog. 1 hit. |
| PROSITE | PS51371. CBS. 2 hits. PS00487. IMP_DH_GMP_RED. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | Q9KTW3_VIBCH | ||||||||
| Accession | Primary (citable) accession number: Q9KTW3 | ||||||||
| Entry history |
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| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||

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