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Q9KTW3 (Q9KTW3_VIBCH) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Inosine-5'-monophosphate dehydrogenase RuleBase RU003928

EC=1.1.1.205 RuleBase RU003928
Gene names
Ordered Locus Names:VC_0767
OrganismVibrio cholerae
Taxonomic identifier666 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio

Protein attributes

Sequence length489 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH. RuleBase RU003928

Pathway

Purine metabolism; XMP biosynthesis via de novo pathway; XMP from IMP: step 1/1. RuleBase RU003928

Sequence similarities

Belongs to the IMPDH/GMPR family. RuleBase RU003927

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site3071Thioimidate intermediate By similarity PIRSR PIRSR000130-1

Sequences

Sequence LengthMass (Da)Tools
Q9KTW3 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: B38133B52F8661C4

FASTA48951,943
        10         20         30         40         50         60 
MHMLRIAKEA LTFDDVLLVP AHSTVLPNTA DLRTRLTKNI ALNIPMVSAS MDTVTEARLA 

        70         80         90        100        110        120 
IALAQEGGIG FIHKNMSIEQ QAAQVHQVKI FEAGVVTHPV TVRPEQTIAD VMELTHYHGF 

       130        140        150        160        170        180 
AGFPVVTENN ELVGIITGRD VRFVTDLTKS VAAVMTPKER LATVKEGATG AEVQEKMHKA 

       190        200        210        220        230        240 
RVEKILVVND EFQLKGMITA KDFHKAESKP NACKDEQGRL RVGAAVGAAP GNEERVKALV 

       250        260        270        280        290        300 
EAGVDVLLID SSHGHSEGVL QRIRETRAAY PHLEIIGGNV ATAEGARALI EAGVSAVKVG 

       310        320        330        340        350        360 
IGPGSICTTR IVTGVGVPQI TAIADAAGVA NEYGIPVIAD GGIRFSGDIS KAIAAGASCV 

       370        380        390        400        410        420 
MVGSMFAGTE EAPGEVILYQ GRSYKAYRGM GSLGAMSKGS SDRYFQTDNA ADKLVPEGIE 

       430        440        450        460        470        480 
GRIAYKGHLK EIIHQQMGGL RSCMGLTGSA TVEDLRTKAQ FVRISGAGMK ESHVHDVQIT 


KEAPNYRLG 

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE003852 Genomic DNA. Translation: AAF93932.1.
PIRC82282.
RefSeqNP_230416.1. NC_002505.1.

3D structure databases

HSSPHSSP built from PDB template 1EEP based on UniProtKB P49058.
ProteinModelPortalQ9KTW3.
SMRQ9KTW3. Positions 5-487.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2615310.
GenomeReviewsGene locus VC_0767 in contig AE003852_GR.
KEGGvch:VC0767.
PATRIC20080645. VBIVibCho83274_0731.
TIGRVC_0767.

Phylogenomic databases

HOGENOMHBG298985.
OMAGIGIVHK.
PhylomeDBQ9KTW3.
ProtClustDBPRK05567.

Family and domain databases

InterProIPR013785. Aldolase_TIM.
IPR000644. Cysta_beta_synth_core.
IPR005990. IMP_DH.
IPR018529. IMP_DH-rel.
IPR015875. IMP_DH/GMP_Rdtase_CS.
IPR001093. IMP_DH_GMPRt.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK00088.
PANTHERPTHR11911:SF6. IMP_DH_GMPRtase. 1 hit.
PfamPF00571. CBS. 2 hits.
PF00478. IMPDH. 1 hit.
[Graphical view]
PIRSFPIRSF000130. IMPDH. 1 hit.
SMARTSM00116. CBS. 2 hits.
[Graphical view]
TIGRFAMsTIGR01302. IMP_dehydrog. 1 hit.
PROSITEPS51371. CBS. 2 hits.
PS00487. IMP_DH_GMP_RED. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ9KTW3_VIBCH
AccessionPrimary (citable) accession number: Q9KTW3
Entry history
Integrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: December 14, 2011
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)