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Q9KTP8 (PPNK_VIBCH) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable inorganic polyphosphate/ATP-NAD kinase

Short name=Poly(P)/ATP NAD kinase
EC=2.7.1.23
Gene names
Name:ppnK
Ordered Locus Names:VC_0853
OrganismVibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) [Reference proteome] [HAMAP]
Taxonomic identifier243277 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio

Protein attributes

Sequence length294 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity. HAMAP-Rule MF_00361

Catalytic activity

ATP + NAD+ = ADP + NADP+. HAMAP-Rule MF_00361

Cofactor

Divalent metal ions By similarity. HAMAP-Rule MF_00361

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00361.

Sequence similarities

Belongs to the NAD kinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
NAD
NADP
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processNAD metabolic process

Inferred from electronic annotation. Source: InterPro

NADP biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

NAD+ kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 294294Probable inorganic polyphosphate/ATP-NAD kinase HAMAP-Rule MF_00361
PRO_0000120686

Sequences

Sequence LengthMass (Da)Tools
Q9KTP8 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 7FEAA38920AAEAE8

FASTA29432,698
        10         20         30         40         50         60 
MKKPFNVLAI IGKPRDQQAI QTHKEIYHWL RSLGYTVFID DRLREILTDL PTEHFASLIE 

        70         80         90        100        110        120 
LGKKADLAIV VGGDGNMLGA ARVLSRFDIS VIGVNRGNLG FLTDLNPEDF QQRLQEVLDG 

       130        140        150        160        170        180 
HYLQETRFLL EAEIHRHGQV KSHNAALNEA VLHPGKIAHM IEFEVYIDDN FAFSQRSDGL 

       190        200        210        220        230        240 
IVSTPTGSTA YSLSGGGPIL SPSLNAITLV PMFPHTLSCR PLVVGGNQRI KLVVSPENRG 

       250        260        270        280        290 
TQEVSCDGQV SLPVSPGDEI HIYQSPNVLK LIHPQDYSYY HVLRTKLGWS SKLF 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE003852 Genomic DNA. Translation: AAF94015.1.
PIRH82272.
RefSeqNP_230500.1. NC_002505.1.

3D structure databases

ProteinModelPortalQ9KTP8.
SMRQ9KTP8. Positions 5-294.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243277.VC0853.

Protocols and materials databases

DNASU2614520.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAF94015; AAF94015; VC_0853.
GeneID2614520.
KEGGvch:VC0853.
PATRIC20080809. VBIVibCho83274_0813.

Phylogenomic databases

eggNOGCOG0061.
KOK00858.
OMAGMVELRV.
OrthoDBEOG6PZXDR.
ProtClustDBPRK03378.

Enzyme and pathway databases

BioCycVCHO:VC0853-MONOMER.

Family and domain databases

Gene3D2.60.200.30. 1 hit.
3.40.50.10330. 1 hit.
HAMAPMF_00361. NAD_kinase.
InterProIPR017438. ATP-NAD_kinase_dom_1.
IPR016064. ATP-NAD_kinase_PpnK-typ.
IPR017437. ATP-NAD_kinase_PpnK-typ_all-b.
IPR002504. PolyP/ATP_NADK_prd.
[Graphical view]
PANTHERPTHR20275. PTHR20275. 1 hit.
PfamPF01513. NAD_kinase. 1 hit.
[Graphical view]
SUPFAMSSF111331. SSF111331. 1 hit.
ProtoNetSearch...

Entry information

Entry namePPNK_VIBCH
AccessionPrimary (citable) accession number: Q9KTP8
Entry history
Integrated into UniProtKB/Swiss-Prot: May 4, 2001
Last sequence update: October 1, 2000
Last modified: February 19, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families