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Protein

Magnesium and cobalt efflux protein CorC

Gene

corC

Organism
Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Plays a role in the transport of magnesium and cobalt ions.By similarity

GO - Molecular functioni

GO - Biological processi

  • hemolysis by symbiont of host erythrocytes Source: TIGR
  • killing of cells of other organism Source: TIGR
  • pathogenesis Source: TIGR
  • transport Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transport

Keywords - Ligandi

Cobalt, Magnesium

Enzyme and pathway databases

BioCyciVCHO:VC0959-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Magnesium and cobalt efflux protein CorC
Gene namesi
Name:corC
Ordered Locus Names:VC_0959
OrganismiVibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Taxonomic identifieri243277 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
Proteomesi
  • UP000000584 Componenti: Chromosome 1

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000883531 – 291Magnesium and cobalt efflux protein CorCAdd BLAST291

Interactioni

Protein-protein interaction databases

STRINGi243277.VC0959.

Structurei

3D structure databases

ProteinModelPortaliQ9KTE3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini71 – 131CBS 1PROSITE-ProRule annotationAdd BLAST61
Domaini136 – 193CBS 2PROSITE-ProRule annotationAdd BLAST58

Sequence similaritiesi

Belongs to the UPF0053 family.Curated
Contains 2 CBS domains.PROSITE-ProRule annotation

Keywords - Domaini

CBS domain, Repeat

Phylogenomic databases

eggNOGiENOG4108JU5. Bacteria.
COG4535. LUCA.
KOiK06189.
OMAiQMISIKA.

Family and domain databases

Gene3Di3.30.465.10. 1 hit.
InterProiIPR000644. CBS_dom.
IPR016169. CO_DH_flavot_FAD-bd_sub2.
IPR016166. FAD-bd_2.
IPR005170. Transptr-assoc_dom.
[Graphical view]
PfamiPF00571. CBS. 2 hits.
PF03471. CorC_HlyC. 1 hit.
[Graphical view]
SMARTiSM00116. CBS. 2 hits.
SM01091. CorC_HlyC. 1 hit.
[Graphical view]
SUPFAMiSSF56176. SSF56176. 1 hit.
PROSITEiPS51371. CBS. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9KTE3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNEDNSQNSE GPSRKSFFER LSQLFQGEPK DRQELVDVIR DSEVNDLIDH
60 70 80 90 100
DTRDMLEGVM EIAEMRVRDI MIPRSQMVTI DRTHNLDALV AIMTDAQHSR
110 120 130 140 150
YPVISEDKDH VEGILLAKDL LKYLGSNCAP FNIQEVIRPA VVVPESKRVD
160 170 180 190 200
RLLKEFREER YHMAIVVDEF GGVSGLVTIE DILEEIVGDI EDEFDDEEQK
210 220 230 240 250
DIRQLSKHTF SVKALTTIED FNHTFGTKFS DEEVDTVGGL VMTAFGHLPA
260 270 280 290
RGEVVDIAGY NFKVTAADSR RVVALQVTVP DLEALSHVAE E
Length:291
Mass (Da):32,916
Last modified:October 1, 2000 - v1
Checksum:i1930D11133B24CE6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE003852 Genomic DNA. Translation: AAF94121.1.
PIRiB82261.
RefSeqiNP_230606.1. NC_002505.1.
WP_001001301.1. NC_002505.1.

Genome annotation databases

EnsemblBacteriaiAAF94121; AAF94121; VC_0959.
GeneIDi2614212.
KEGGivch:VC0959.
PATRICi20081018. VBIVibCho83274_0913.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE003852 Genomic DNA. Translation: AAF94121.1.
PIRiB82261.
RefSeqiNP_230606.1. NC_002505.1.
WP_001001301.1. NC_002505.1.

3D structure databases

ProteinModelPortaliQ9KTE3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243277.VC0959.

Protocols and materials databases

DNASUi2614212.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAF94121; AAF94121; VC_0959.
GeneIDi2614212.
KEGGivch:VC0959.
PATRICi20081018. VBIVibCho83274_0913.

Phylogenomic databases

eggNOGiENOG4108JU5. Bacteria.
COG4535. LUCA.
KOiK06189.
OMAiQMISIKA.

Enzyme and pathway databases

BioCyciVCHO:VC0959-MONOMER.

Family and domain databases

Gene3Di3.30.465.10. 1 hit.
InterProiIPR000644. CBS_dom.
IPR016169. CO_DH_flavot_FAD-bd_sub2.
IPR016166. FAD-bd_2.
IPR005170. Transptr-assoc_dom.
[Graphical view]
PfamiPF00571. CBS. 2 hits.
PF03471. CorC_HlyC. 1 hit.
[Graphical view]
SMARTiSM00116. CBS. 2 hits.
SM01091. CorC_HlyC. 1 hit.
[Graphical view]
SUPFAMiSSF56176. SSF56176. 1 hit.
PROSITEiPS51371. CBS. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCORC_VIBCH
AccessioniPrimary (citable) accession number: Q9KTE3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 1, 2001
Last sequence update: October 1, 2000
Last modified: November 30, 2016
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.