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Q9KTA6 (SYQ_VIBCH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glutamine--tRNA ligase
EC=6.1.1.18
Alternative name(s):
Glutaminyl-tRNA synthetase
Short name=GlnRS
Gene names
Name:glnS
Ordered Locus Names:VC_0997
OrganismVibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) [Reference proteome] [HAMAP]
Taxonomic identifier243277 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio ›

Protein attributes

Sequence length556 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln). HAMAP-Rule MF_00126

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00126

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00126.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 556556Glutamine--tRNA ligase HAMAP-Rule MF_00126
PRO_0000195852

Regions

Motif34 – 4411"HIGH" region HAMAP-Rule MF_00126
Motif268 – 2725"KMSKS" region HAMAP-Rule MF_00126

Sites

Binding site2711ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9KTA6 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 8108C0366F0760F8

FASTA55664,089
        10         20         30         40         50         60 
MSEAEARPSN FIRQIIDKDL ADGKHTTVHT RFPPEPNGYL HIGHAKSICL NFGIAQDYQG 

        70         80         90        100        110        120 
QCNLRFDDTN PEKENLEYVE SIKKDVTWLG FDWSGEVCYS SDYFDKLYEY AIELIQKGLA 

       130        140        150        160        170        180 
YVDELTPEQI REYRGTLTEP GKHSPYRDRS VEENLALFEK MRAGEFAEGQ ACLRAKIDMA 

       190        200        210        220        230        240 
SSFIVMRDPV LYRVRFAEHH QTGDKWCIYP MYDFTHCISD ALEGITHSIC TLEFQDNRRL 

       250        260        270        280        290        300 
YDWVLDNITI PCHPRQYEFS RLNLEYTVMS KRKLNQLVTE KLVTGWDDPR MPTISGLRRR 

       310        320        330        340        350        360 
GFTPSAIREF CKRIGVTKQE NMIEYSALES CIRDDLNENA PRAMAVLDPV KLVIENFAAG 

       370        380        390        400        410        420 
TVETLTLANH PNKPEMGDRE VPFTRELWIE REDFREEANK KYKRLVLGKE VRLRGAYVIK 

       430        440        450        460        470        480 
AERIEKDEQG NITTIFCSYD PETLGKNPAD GRKVKGVIHW VSAEKGVPAE FRLYERLFTV 

       490        500        510        520        530        540 
PNPGAADNFA ETINPESLVK VQGYVEPSLV EAKPEFGYQF ERMGYFCADN KDSSPQALVF 

       550 
NRTVGLRDSF AKIDEE

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE003852 Genomic DNA. Translation: AAF94158.1.
PIRH82254.
PC4398.
RefSeqNP_230643.1. NC_002505.1.

3D structure databases

ProteinModelPortalQ9KTA6.
SMRQ9KTA6. Positions 9-549.
ModBaseSearch...

Protein-protein interaction databases

STRING243277.VC0997.

Proteomic databases

PRIDEQ9KTA6.

Protocols and materials databases

DNASU2614250.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAF94158; AAF94158; VC_0997.
GeneID2614250.
KEGGvch:VC0997.
PATRIC20081092. VBIVibCho83274_0950.

Phylogenomic databases

eggNOGCOG0008.
KOK01886.
OMARMPTIAG.
ProtClustDBPRK05347.

Family and domain databases

Gene3D1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
HAMAPMF_00126. Gln_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth_Ib.
IPR022861. Gln_tRNA_ligase_bac.
IPR000924. Glu/Gln-tRNA-synth_Ib.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERPTHR10119. PTHR10119. 1 hit.
PfamPF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
[Graphical view]
PRINTSPR00987. TRNASYNTHGLU.
SUPFAMSSF50715. Ribosomal_L25rel. 1 hit.
TIGRFAMsTIGR00440. glnS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYQ_VIBCH
AccessionPrimary (citable) accession number: Q9KTA6
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: October 1, 2000
Last modified: May 1, 2013
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries

SIMILARITY comments

Index of protein domains and families

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