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Q9KT08 (PTA_VIBCH) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphate acetyltransferase

EC=2.3.1.8
Alternative name(s):
Phosphotransacetylase
Gene names
Name:pta
Ordered Locus Names:VC_1097
OrganismVibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) [Reference proteome] [HAMAP]
Taxonomic identifier243277 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio

Protein attributes

Sequence length714 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in acetate metabolism By similarity.

Catalytic activity

Acetyl-CoA + phosphate = CoA + acetyl phosphate.

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 2/2.

Subunit structure

Homohexamer By similarity.

Subcellular location

Cytoplasm Potential.

Domain

The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site By similarity.

Sequence similarities

In the N-terminal section; belongs to the CobB/CobQ family.

In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionAcyltransferase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processacetyl-CoA biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

fermentation

Inferred from sequence or structural similarity Ref.1. Source: TIGR

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionphosphate acetyltransferase activity

Inferred from sequence or structural similarity Ref.1. Source: TIGR

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 714714Phosphate acetyltransferase
PRO_0000405554

Regions

Region390 – 714325Phosphate acetyltransferase

Sequences

Sequence LengthMass (Da)Tools
Q9KT08 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 18B90F0A6D87AC80

FASTA71476,892
        10         20         30         40         50         60 
MSRTIMLIPI SAGVGLTSVS MGLLRAMERK GVSVSFYKPI AQPRTGDDQP DLTSTVMSRN 

        70         80         90        100        110        120 
SDIKIGQPMS MSAAETLIGS EKMDVLLETV VERYNQINKD AEVTLIEGLV PTRKHPFANQ 

       130        140        150        160        170        180 
VNAEIANTLG AEIVFVATPG TDNPTQLKER IEVACSNFGG TKNKSISGVI INKLNAPVDE 

       190        200        210        220        230        240 
AGRTRPDLSE IFDDADHAKQ ANLEVMQIFN TSPIRVLGCV PWSIDLIATR AIDMAKHLKA 

       250        260        270        280        290        300 
EIINQGDINT RRIKSITFCA RSIPNMIEHF KPGSLLVTSA DRPDVIVAAA LAAMNGVEIG 

       310        320        330        340        350        360 
AVLLTGGYDI PRELVSLCKP AFDTGLPIFK AQGNTWQTSL NLQSFSLEVP ADDKERIEFI 

       370        380        390        400        410        420 
SEHVASHIDG PWVDSLTEGA QASRRLSPPA FRYQLTELAR SANKRIVLPE GDEPRTVKAA 

       430        440        450        460        470        480 
AICAERGIAQ CVLLGNPEEI KRVAAQQGVE LGSGIEIIDP KVAQEKYVAR LVELRKSKGM 

       490        500        510        520        530        540 
TEVVAREQLE DTVVLGTMML ERNEVDGLVS GAVHTTANTI RPPLQIIKTA PNASLVSSIF 

       550        560        570        580        590        600 
FMLLPDQVLV YGDCAINPDP NAEQLAEIAI QSADSAAAFG IEPRVAMISY STGTSGQGAD 

       610        620        630        640        650        660 
VDKVREATRI AKEKRPDLVI DGPLQYDAAI MENVAASKAP NSPVAGKATV FVFPDLNTGN 

       670        680        690        700        710 
TTYKAVQRSA DLVSIGPMLQ GMRKPVNDLS RGALVDDIVY TIALTAIQAG QEQK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE003852 Genomic DNA. Translation: AAF94256.1.
PIRH82242.
RefSeqNP_230742.1. NC_002505.1.

3D structure databases

ProteinModelPortalQ9KT08.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243277.VC1097.

Proteomic databases

PRIDEQ9KT08.

Protocols and materials databases

DNASU2614367.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAF94256; AAF94256; VC_1097.
GeneID2614367.
KEGGvch:VC1097.
PATRIC20081288. VBIVibCho83274_1047.

Phylogenomic databases

eggNOGCOG0280.
KOK13788.
OMAKPIAQPH.
OrthoDBEOG6BKJ5W.

Enzyme and pathway databases

BioCycVCHO:VC1097-MONOMER.
UniPathwayUPA00340; UER00459.

Family and domain databases

Gene3D3.40.1390.20. 1 hit.
3.40.50.300. 1 hit.
InterProIPR010766. DRTGG.
IPR016475. P-Actrans_bac.
IPR027417. P-loop_NTPase.
IPR004614. P_AcTrfase.
IPR002505. PTA_PTB.
IPR028979. Ser_kin/Pase_Hpr_N_like.
[Graphical view]
PfamPF07085. DRTGG. 1 hit.
PF01515. PTA_PTB. 1 hit.
[Graphical view]
PIRSFPIRSF006107. PhpActrans_proteobac. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
SSF75138. SSF75138. 1 hit.
TIGRFAMsTIGR00651. pta. 1 hit.
ProtoNetSearch...

Entry information

Entry namePTA_VIBCH
AccessionPrimary (citable) accession number: Q9KT08
Entry history
Integrated into UniProtKB/Swiss-Prot: March 8, 2011
Last sequence update: October 1, 2000
Last modified: June 11, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways