Q9KST2 (TRPE_VIBCH) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 70.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Anthranilate synthase component 1 EC=4.1.3.27 Alternative name(s): Anthranilate synthase component I | ||||
| Gene names |
| ||||
| Organism | Vibrio cholerae | ||||
| Taxonomic identifier | 666 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio |
Protein attributes
| Sequence length | 523 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Catalytic activity | Chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate. |
| Pathway | Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 1/5. |
| Subunit structure | Tetramer of two components I and two components II By similarity. |
| Miscellaneous | Component I catalyzes the formation of anthranilate using ammonia rather than glutamine, whereas component II provides glutamine amidotransferase activity. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis |
| Molecular function | Lyase |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological process | tryptophan biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | anthranilate synthase activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 523 | 523 | Anthranilate synthase component 1 | PRO_0000154118 | |||
Sequences
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References
| [1] | "DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae." Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L., Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R., Nelson K.E., Read T.D., Tettelin H., Richardson D.L., Ermolaeva M.D., Vamathevan J.J., Bass S. Fraser C.M.Nature 406:477-483(2000) [PubMed: 10952301] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 39315 / El Tor Inaba N16961 / Serotype O1. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AE003852 Genomic DNA. Translation: AAF94333.1. |
| PIR | A82233. |
| RefSeq | NP_230819.1. NC_002505.1. |
3D structure databases | |
| ProteinModelPortal | Q9KST2. |
| SMR | Q9KST2. Positions 13-521. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 2614607. |
| GenomeReviews | Gene locus VC_1174 in contig AE003852_GR. |
| KEGG | vch:VC1174. |
| PATRIC | 20081440. VBIVibCho83274_1123. |
| TIGR | VC_1174. |
Phylogenomic databases | |
| HOGENOM | HBG507440. |
| OMA | NDIARVC. |
| PhylomeDB | Q9KST2. |
| ProtClustDB | PRK13564. |
Family and domain databases | |
| InterPro | IPR005801. ADC_synthase. IPR019999. Anth_synth_I. IPR006805. Anth_synth_I_N. IPR005257. Anth_synth_I_TrpE. IPR015890. Chorismate-bd_C. [Graphical view] |
| Gene3D | G3DSA:3.60.120.10. TRPE_1_chor_bd. 1 hit. |
| KO | K01657. |
| Pfam | PF04715. Anth_synt_I_N. 1 hit. PF00425. Chorismate_bind. 1 hit. [Graphical view] |
| PRINTS | PR00095. ANTSNTHASEI. |
| SUPFAM | SSF56322. TRPE_1_chor_bd. 1 hit. |
| TIGRFAMs | TIGR00565. TrpE_proteo. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | TRPE_VIBCH | ||||||||
| Accession | Primary (citable) accession number: Q9KST2 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |

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