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Q9KRV2 (NAGK_VIBCH) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
N-acetyl-D-glucosamine kinase

EC=2.7.1.59
Alternative name(s):
GlcNAc kinase
Gene names
Name:nagK
Ordered Locus Names:VC_1532
OrganismVibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) [Reference proteome] [HAMAP]
Taxonomic identifier243277 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio

Protein attributes

Sequence length302 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P By similarity. HAMAP-Rule MF_01271

Catalytic activity

ATP + N-acetyl-D-glucosamine = ADP + N-acetyl-D-glucosamine 6-phosphate. HAMAP-Rule MF_01271

Pathway

Cell wall biogenesis; peptidoglycan recycling. HAMAP-Rule MF_01271

Sequence similarities

Belongs to the ROK (NagC/XylR) family. NagK subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 302302N-acetyl-D-glucosamine kinase HAMAP-Rule MF_01271
PRO_0000270119

Regions

Nucleotide binding4 – 118ATP Potential
Nucleotide binding133 – 1408ATP Potential

Sites

Metal binding1571Zinc By similarity
Metal binding1771Zinc By similarity
Metal binding1791Zinc By similarity
Metal binding1841Zinc By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9KRV2 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 5B21F13445425464

FASTA30232,603
        10         20         30         40         50         60 
MYYGFDVGGT KIEFGAFNEQ LERVATERVA TPTDDYAKLV ETIAGLVHKY DAQFGVEGTV 

        70         80         90        100        110        120 
GLGIPGMEDA DNGCVLTVNV PAAKGKPLRA DLETKLGRAV KVENDANCFA LSEAWDDELK 

       130        140        150        160        170        180 
EAASVMGLIL GTGFGGGLVY EGKVFSGRNH VAGEIGHMRL PIDAWFHLGE KAPLLGCGCG 

       190        200        210        220        230        240 
NKGCMDNYLS GRGFELLYEH YYGEKKKAID IITAQKEGES KAVEHVERFM ELLAICFANI 

       250        260        270        280        290        300 
FTANDPHVVV LGGGLSNYDL IYEEMPKRVP KHLLSVAKCP KIVKAKHGDS GGVRGAAFLN 


IK 

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE003852 Genomic DNA. Translation: AAF94686.1.
PIRB82189.
RefSeqNP_231172.1. NC_002505.1.

3D structure databases

ProteinModelPortalQ9KRV2.
SMRQ9KRV2. Positions 1-301.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243277.VC1532.

Protocols and materials databases

DNASU2613911.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAF94686; AAF94686; VC_1532.
GeneID2613911.
KEGGvch:VC1532.
PATRIC20082123. VBIVibCho83274_1460.

Phylogenomic databases

eggNOGCOG1940.
KOK00884.
OMAEHVDRFM.
OrthoDBEOG61P6P0.
ProtClustDBPRK13310.

Enzyme and pathway databases

BioCycVCHO:VC1532-MONOMER.
UniPathwayUPA00544.

Family and domain databases

HAMAPMF_01271. GlcNAc_kinase.
InterProIPR023505. N-acetyl-D-glucosamine_kinase.
IPR000600. ROK.
[Graphical view]
PfamPF00480. ROK. 1 hit.
[Graphical view]
PROSITEPS01125. ROK. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameNAGK_VIBCH
AccessionPrimary (citable) accession number: Q9KRV2
Entry history
Integrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: October 1, 2000
Last modified: April 16, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways