Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q9KRA7

- LFTR_VIBCH

UniProt

Q9KRA7 - LFTR_VIBCH

Protein

Leucyl/phenylalanyl-tRNA--protein transferase

Gene

aat

Organism
Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 72 (01 Oct 2014)
      Sequence version 1 (01 Oct 2000)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.UniRule annotation

    Catalytic activityi

    L-leucyl-tRNA(Leu) + [protein] = tRNA(Leu) + L-leucyl-[protein].UniRule annotation
    L-phenylalanyl-tRNA(Phe) + [protein] = tRNA + L-phenylalanyl-[protein].UniRule annotation

    GO - Molecular functioni

    1. leucyltransferase activity Source: UniProtKB-EC
    2. peptidase activity Source: TIGR

    GO - Biological processi

    1. protein catabolic process Source: InterPro
    2. proteolysis Source: TIGR

    Keywords - Molecular functioni

    Acyltransferase, Transferase

    Enzyme and pathway databases

    BioCyciVCHO:VC1735-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Leucyl/phenylalanyl-tRNA--protein transferaseUniRule annotation (EC:2.3.2.6UniRule annotation)
    Alternative name(s):
    L/F-transferaseUniRule annotation
    LeucyltransferaseUniRule annotation
    PhenyalanyltransferaseUniRule annotation
    Gene namesi
    Name:aatUniRule annotation
    Ordered Locus Names:VC_1735
    OrganismiVibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
    Taxonomic identifieri243277 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
    ProteomesiUP000000584: Chromosome 1

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 243243Leucyl/phenylalanyl-tRNA--protein transferasePRO_0000207247Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi243277.VC1735.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9KRA7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the L/F-transferase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2360.
    KOiK00684.
    OMAiWSPDPRG.
    OrthoDBiEOG6WX4R3.

    Family and domain databases

    HAMAPiMF_00688. Leu_Phe_trans.
    InterProiIPR016181. Acyl_CoA_acyltransferase.
    IPR004616. Leu/Phe-tRNA_Trfase.
    [Graphical view]
    PfamiPF03588. Leu_Phe_trans. 1 hit.
    [Graphical view]
    SUPFAMiSSF55729. SSF55729. 1 hit.
    TIGRFAMsiTIGR00667. aat. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q9KRA7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAIYLTELSP ETLTFPSPFT ALDDPNGLLA FGGDLRLERI WAAYQQGIFP    50
    WYGPEDPILW WSPSPRAVFD PTRFQPAKSV KKFQRKHQYR VSVNHATSQV 100
    IEQCALTRPA DQRWLNDSMR HAYGELAKQG RCHSVEVWQG EQLVGGLYGI 150
    SVGQLFCGES MFSLATNASK IALWYFCDHF SRHQGQLIDC QVMNPHLQSL 200
    GATTLSREQF IQSLLSFKEK QVLSGCFETQ WLATPTSPCA FED 243
    Length:243
    Mass (Da):27,569
    Last modified:October 1, 2000 - v1
    Checksum:i24AF885AE888D515
    GO

    Sequence cautioni

    The sequence AAB87633.1 differs from that shown. Reason: Frameshift at position 206.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE003852 Genomic DNA. Translation: AAF94885.1.
    AF035002 Genomic DNA. Translation: AAB87633.1. Frameshift.
    PIRiG82163.
    RefSeqiNP_231371.1. NC_002505.1.

    Genome annotation databases

    EnsemblBacteriaiAAF94885; AAF94885; VC_1735.
    GeneIDi2613740.
    KEGGivch:VC1735.
    PATRICi20082524. VBIVibCho83274_1658.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE003852 Genomic DNA. Translation: AAF94885.1 .
    AF035002 Genomic DNA. Translation: AAB87633.1 . Frameshift.
    PIRi G82163.
    RefSeqi NP_231371.1. NC_002505.1.

    3D structure databases

    ProteinModelPortali Q9KRA7.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 243277.VC1735.

    Protocols and materials databases

    DNASUi 2613740.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAF94885 ; AAF94885 ; VC_1735 .
    GeneIDi 2613740.
    KEGGi vch:VC1735.
    PATRICi 20082524. VBIVibCho83274_1658.

    Phylogenomic databases

    eggNOGi COG2360.
    KOi K00684.
    OMAi WSPDPRG.
    OrthoDBi EOG6WX4R3.

    Enzyme and pathway databases

    BioCyci VCHO:VC1735-MONOMER.

    Family and domain databases

    HAMAPi MF_00688. Leu_Phe_trans.
    InterProi IPR016181. Acyl_CoA_acyltransferase.
    IPR004616. Leu/Phe-tRNA_Trfase.
    [Graphical view ]
    Pfami PF03588. Leu_Phe_trans. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55729. SSF55729. 1 hit.
    TIGRFAMsi TIGR00667. aat. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 39315 / El Tor Inaba N16961.
    2. "Substrate recognition by the leucyl/phenylalanyl-tRNA-protein transferase. Conservation within the enzyme family and localization to the trypsin-resistant domain."
      Ichetovkin I.E., Abramochkin G., Shrader T.E.
      J. Biol. Chem. 272:33009-33014(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-208.

    Entry informationi

    Entry nameiLFTR_VIBCH
    AccessioniPrimary (citable) accession number: Q9KRA7
    Secondary accession number(s): O50259
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 25, 2003
    Last sequence update: October 1, 2000
    Last modified: October 1, 2014
    This is version 72 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3