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Protein
Submitted name:

Transcriptional regulator, HTH_3 family

Gene

VC_1968

Organism
Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi120 – 1201Zinc; via tele nitrogenCombined sources
Metal bindingi126 – 1261ZincCombined sources
Metal bindingi160 – 1601Zinc; via tele nitrogenCombined sources
Metal bindingi162 – 1621ZincCombined sources

GO - Molecular functioni

GO - Biological processi

  • regulation of transcription, DNA-templated Source: TIGR
Complete GO annotation...

Keywords - Ligandi

Metal-bindingCombined sources, ZincCombined sources

Enzyme and pathway databases

BioCyciVCHO:VC1968-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Transcriptional regulator, HTH_3 familyImported
Gene namesi
Ordered Locus Names:VC_1968Imported
OrganismiVibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)Imported
Taxonomic identifieri243277 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
Proteomesi
  • UP000000584 Componenti: Chromosome 1

Interactioni

Protein-protein interaction databases

STRINGi243277.VC1968.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1Y9QX-ray1.90A2-180[»]
ProteinModelPortaliQ9KQN0.
SMRiQ9KQN0. Positions 2-179.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9KQN0.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini14 – 6855HTH cro/C1-type DNA-bindingInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiENOG4108JCI. Bacteria.
COG1396. LUCA.
OMAiHYERLSE.
OrthoDBiEOG615VS0.

Family and domain databases

Gene3Di1.10.260.40. 1 hit.
2.60.120.10. 1 hit.
InterProiIPR001387. Cro/C1-type_HTH.
IPR010982. Lambda_DNA-bd_dom.
IPR014710. RmlC-like_jellyroll.
IPR011051. RmlC_Cupin.
[Graphical view]
PfamiPF01381. HTH_3. 1 hit.
[Graphical view]
SMARTiSM00530. HTH_XRE. 1 hit.
[Graphical view]
SUPFAMiSSF47413. SSF47413. 1 hit.
SSF51182. SSF51182. 1 hit.
PROSITEiPS50943. HTH_CROC1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9KQN0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDVMFKSQI ANQLKNLRKS RGLSLDATAQ LTGVSKAMLG QIERGESSPT
60 70 80 90 100
IATLWKIASG LEASFSAFFA NDPQLLSSER SFPDDLNMKI HTLFPYAADT
110 120 130 140 150
GLEIFEITLL DHHQQMSSPH ALGVIEYIHV LEGIMKVFFD EQWHELQQGE
160 170 180
HIRFFSDQPH GYAAVTEKAV FQNIVAYPRR G
Length:181
Mass (Da):20,354
Last modified:October 1, 2000 - v1
Checksum:i205020F270ED91DF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE003852 Genomic DNA. Translation: AAF95116.1.
PIRiB82134.
RefSeqiNP_231602.1. NC_002505.1.
WP_000133005.1. NC_002505.1.

Genome annotation databases

EnsemblBacteriaiAAF95116; AAF95116; VC_1968.
GeneIDi2613472.
KEGGivch:VC1968.
PATRICi20082974. VBIVibCho83274_1881.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE003852 Genomic DNA. Translation: AAF95116.1.
PIRiB82134.
RefSeqiNP_231602.1. NC_002505.1.
WP_000133005.1. NC_002505.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1Y9QX-ray1.90A2-180[»]
ProteinModelPortaliQ9KQN0.
SMRiQ9KQN0. Positions 2-179.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243277.VC1968.

Protocols and materials databases

DNASUi2613472.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAF95116; AAF95116; VC_1968.
GeneIDi2613472.
KEGGivch:VC1968.
PATRICi20082974. VBIVibCho83274_1881.

Phylogenomic databases

eggNOGiENOG4108JCI. Bacteria.
COG1396. LUCA.
OMAiHYERLSE.
OrthoDBiEOG615VS0.

Enzyme and pathway databases

BioCyciVCHO:VC1968-MONOMER.

Miscellaneous databases

EvolutionaryTraceiQ9KQN0.

Family and domain databases

Gene3Di1.10.260.40. 1 hit.
2.60.120.10. 1 hit.
InterProiIPR001387. Cro/C1-type_HTH.
IPR010982. Lambda_DNA-bd_dom.
IPR014710. RmlC-like_jellyroll.
IPR011051. RmlC_Cupin.
[Graphical view]
PfamiPF01381. HTH_3. 1 hit.
[Graphical view]
SMARTiSM00530. HTH_XRE. 1 hit.
[Graphical view]
SUPFAMiSSF47413. SSF47413. 1 hit.
SSF51182. SSF51182. 1 hit.
PROSITEiPS50943. HTH_CROC1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 39315 / El Tor Inaba N16961Imported.
  2. "Crystal Structure of HTH_3 family Transcriptional Regulator from Vibrio cholerae."
    New York Structural Genomics Research Consortium (NYSGRC)
    Kumaran D., Swaminathan S.
    Submitted (DEC-2004) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS) OF 2-180 IN COMPLEX WITH ZINC.

Entry informationi

Entry nameiQ9KQN0_VIBCH
AccessioniPrimary (citable) accession number: Q9KQN0
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: March 16, 2016
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.