Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q9KPR9 (RLMG_VIBCH) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribosomal RNA large subunit methyltransferase G
EC=2.1.1.174
Alternative name(s):
23S rRNA m2G1835 methyltransferase
rRNA (guanine-N(2)-)-methyltransferase RlmG
Gene names
Name:rlmG
Ordered Locus Names:VC_2297
OrganismVibrio cholerae
Taxonomic identifier666 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio

Protein attributes

Sequence length376 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Specifically methylates the guanosine in position 1835 (m2G1835) of 23S rRNA By similarity. HAMAP MF_01859

Catalytic activity

S-adenosyl-L-methionine + guanosine(1835) in 23S rRNA = S-adenosyl-L-homocysteine + N(2)-methylguanosine(1835) in 23S rRNA. HAMAP MF_01859

Subcellular location

Cytoplasm Potential HAMAP MF_01859.

Sequence similarities

Belongs to the methyltransferase superfamily. RlmG family.

Sequence caution

The sequence AAF95441.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Biological processrRNA processing
   Cellular componentCytoplasm
   LigandS-adenosyl-L-methionine
   Molecular functionMethyltransferase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionnucleic acid binding

Inferred from electronic annotation. Source: InterPro

rRNA (guanine-N2-)-methyltransferase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 376376Ribosomal RNA large subunit methyltransferase G HAMAP MF_01859
PRO_0000366530

Sequences

Sequence LengthMass (Da)Tools
Q9KPR9 [UniParc].

Last modified March 24, 2009. Version 2.
Checksum: FB166ECA68CBA65F

FASTA37642,051
        10         20         30         40         50         60 
MKTELTLLEQ TLTLHRFPKR NNETLQAWDA GDEYLIQHVE QLALPESSHI VIINDHFGTL 

        70         80         90        100        110        120 
SCWFSQKHKV SMMSDSYIAH QATQANLQQN QRPPVQLLTT LDPVPNDASV VLLQLPKSNR 

       130        140        150        160        170        180 
HLVWILSQLR KALSPNIPII AVNKAKEIHT STLNLFEKHL GPTTTSLAWK KHRLVFSSAT 

       190        200        210        220        230        240 
VNPANEVNPE CGWSIEPYAI TLTNLPNVYS GESLDLGSRF ILEHLPADPT LEDFIDLGCG 

       250        260        270        280        290        300 
NGVLSVRLGQ LNPQAKITCV DESFMAIASA QKNLHDNLGK RDIHCIANNC LDGFPAHSSS 

       310        320        330        340        350        360 
MIVCNPPFHQ QQTITDHIAW QMFCDSKHVL KKGGKLWVIG NRHLGYDVKL ARLFGKSHVR 

       370 
VIANNSKFVI LQAIKS

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE003852 Genomic DNA. Translation: AAF95441.1. Different initiation.
PIRA82095.
RefSeqNP_231928.1. NC_002505.1.

3D structure databases

ProteinModelPortalQ9KPR9.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2613093.
GenomeReviewsGene locus VC_2297 in contig AE003852_GR.
KEGGvch:VC2297.
PATRIC20083633. VBIVibCho83274_2191.
TIGRVC_2297.

Phylogenomic databases

HOGENOMHBG321931.
OMANRHLGYH.
ProtClustDBCLSK874746.

Family and domain databases

HAMAPMF_01859. 23SrRNA_methyltr_G.
[Tree]
InterProIPR002052. DNA_methylase_N6_adenine_CS.
IPR017237. rRNA_m2G-MeTrfase_RsmD.
IPR007848. Small_mtfrase.
[Graphical view]
KOK00564.
PfamPF05175. MTS. 1 hit.
[Graphical view]
PIRSFPIRSF037565. RRNA_m2G_Mtase_RsmD_prd. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRLMG_VIBCH
AccessionPrimary (citable) accession number: Q9KPR9
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: March 24, 2009
Last modified: January 25, 2012
This is version 58 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents