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Protein

Ribonuclease R

Gene

rnr

Organism
Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.UniRule annotation

Catalytic activityi

Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.UniRule annotation

GO - Molecular functioni

  • exoribonuclease II activity Source: UniProtKB-EC
  • ribonuclease R activity Source: TIGR
  • RNA binding Source: UniProtKB-KW

GO - Biological processi

  • RNA processing Source: TIGR

Keywordsi

Molecular functionExonuclease, Hydrolase, Nuclease, RNA-binding

Enzyme and pathway databases

BioCyciVCHO:VC2599-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease RUniRule annotation (EC:3.1.13.1UniRule annotation)
Short name:
RNase RUniRule annotation
Gene namesi
Name:rnrUniRule annotation
Ordered Locus Names:VC_2599
OrganismiVibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Taxonomic identifieri243277 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
Proteomesi
  • UP000000584 Componenti: Chromosome 1

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001664151 – 821Ribonuclease RAdd BLAST821

Proteomic databases

PRIDEiQ9KNY1

Interactioni

Protein-protein interaction databases

STRINGi243277.VC2599

Structurei

3D structure databases

ProteinModelPortaliQ9KNY1
SMRiQ9KNY1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini652 – 733S1 motifUniRule annotationAdd BLAST82

Sequence similaritiesi

Belongs to the RNR ribonuclease family. RNase R subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C40 Bacteria
COG0557 LUCA
KOiK12573
OMAiDWYEYRS

Family and domain databases

HAMAPiMF_01895 RNase_R, 1 hit
InterProiView protein in InterPro
IPR011129 CSD
IPR012340 NA-bd_OB-fold
IPR013223 RNase_B_OB_dom
IPR022966 RNase_II/R_CS
IPR004476 RNase_II/RNase_R
IPR011805 RNase_R
IPR013668 RNase_R_HTH_12
IPR022967 S1_dom
IPR003029 S1_domain
PfamiView protein in Pfam
PF08461 HTH_12, 1 hit
PF08206 OB_RNB, 1 hit
PF00575 S1, 1 hit
SMARTiView protein in SMART
SM00357 CSP, 1 hit
SM00316 S1, 1 hit
SUPFAMiSSF50249 SSF50249, 4 hits
TIGRFAMsiTIGR00358 3_prime_RNase, 1 hit
TIGR02063 RNase_R, 1 hit
PROSITEiView protein in PROSITE
PS01175 RIBONUCLEASE_II, 1 hit
PS50126 S1, 1 hit

Sequencei

Sequence statusi: Complete.

Q9KNY1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDTTHLDPF ADREADNYDN PIPSREYILE FLTQANVPMN RNDLFEALKL
60 70 80 90 100
EGEEQYEGLR RRLRAMERDG QLVFTRRQCY ALPEKLEMVK GYVIGHKDGH
110 120 130 140 150
GWVRPEGSLN KEGDILLPHH QMRTLIHGDF VLVQPSGTDK RGRKEGRLVR
160 170 180 190 200
ILEERNGQIV GRFFFEYGYS YVVPDDSRIH HDILIPNDLR AGARMGNVVV
210 220 230 240 250
IEITDRGTRN RGMMGKVVEV LGENMAPGME TQIAIRTHQI PHEWPAEVEQ
260 270 280 290 300
QVAGLTEEVP EEAKQGRVDL RALPLVTIDG EDARDFDDAV YCEAKKGGGW
310 320 330 340 350
RLWVAIADVS YYVRPDTALD KEAINRGNSV YFPSQVVPML PEVLSNGLCS
360 370 380 390 400
LNPQVDRLCM VCEMTVSETG KLSGYKHYEA VMNSHARLTY TKVHEILEGD
410 420 430 440 450
EELRERYKAL VPHLEELHKM YQVLKSARDE RGAIEFETVE TKFIFNAQRK
460 470 480 490 500
IESIEPVVRN DAHKLIEECM ILANIASASL VEKAKEAALY RVHEPPGEER
510 520 530 540 550
LTGFRDFLGE LGLDLSGGLE PSPTDYANLM KQIGERPDKE LIQTMLLRSM
560 570 580 590 600
KQAVYNADNA GHFGLALKRY AHFTSPIRRY PDLLLHRAIK YLIAKQEGRN
610 620 630 640 650
QDRWTPTGGY HYSFDDMDFY GEQCSMTERR ADDATREVSD WLKCEYMQDH
660 670 680 690 700
VGEELEGVVA NVTSFGFFVR LTELHIDGLV HISTLANDYY HYDPIGQRLV
710 720 730 740 750
GESFGAIYRL GDAVKVKVLA VNLDDRQIDF ELVETSRKLR GQGKTAKKRA
760 770 780 790 800
DEARAKAQGK KEAATKGACG KSPTKSELKP QVEATRRPDS EGRSKPKKTK
810 820
APKKRKDQAR KKSGKVRDKT K
Length:821
Mass (Da):93,334
Last modified:October 1, 2000 - v1
Checksum:iE3AE7441097447D9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE003852 Genomic DNA Translation: AAF95740.1
PIRiC82055
RefSeqiNP_232227.1, NC_002505.1
WP_001285863.1, NC_002505.1

Genome annotation databases

EnsemblBacteriaiAAF95740; AAF95740; VC_2599
GeneIDi2615616
KEGGivch:VC2599
PATRICifig|243277.26.peg.2478

Similar proteinsi

Entry informationi

Entry nameiRNR_VIBCH
AccessioniPrimary (citable) accession number: Q9KNY1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 23, 2002
Last sequence update: October 1, 2000
Last modified: May 23, 2018
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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