SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9KNT5

- ARGE_VIBCH

UniProt

Q9KNT5 - ARGE_VIBCH

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Acetylornithine deacetylase
Gene
argE, VC_2645
Organism
Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

N(2)-acetyl-L-ornithine + H2O = acetate + L-ornithine.UniRule annotation

Cofactori

Binds 2 zinc or cobalt ions per subunit By similarity.UniRule annotation
Glutathione By similarity.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi76 – 761Cobalt or zinc 1 By similarity
Active sitei78 – 781 By similarity
Metal bindingi108 – 1081Cobalt or zinc 1 By similarity
Metal bindingi108 – 1081Cobalt or zinc 2 By similarity
Active sitei140 – 1401Proton acceptor By similarity
Metal bindingi141 – 1411Cobalt or zinc 2 By similarity
Metal bindingi165 – 1651Cobalt or zinc 1 By similarity
Metal bindingi351 – 3511Cobalt or zinc 2 By similarity

GO - Molecular functioni

  1. acetylornithine deacetylase activity Source: TIGR
  2. cobalt ion binding Source: InterPro
  3. metallopeptidase activity Source: InterPro
  4. zinc ion binding Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. arginine biosynthetic process Source: TIGR
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Amino-acid biosynthesis, Arginine biosynthesis

Keywords - Ligandi

Cobalt, Metal-binding, Zinc

Enzyme and pathway databases

BioCyciVCHO:VC2645-MONOMER.
UniPathwayiUPA00068; UER00110.

Protein family/group databases

MEROPSiM20.974.

Names & Taxonomyi

Protein namesi
Recommended name:
Acetylornithine deacetylase (EC:3.5.1.16)
Short name:
AO
Short name:
Acetylornithinase
Alternative name(s):
N-acetylornithinase
Short name:
NAO
Gene namesi
Name:argE
Ordered Locus Names:VC_2645
OrganismiVibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Taxonomic identifieri243277 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
ProteomesiUP000000584: Chromosome 1

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 378378Acetylornithine deacetylaseUniRule annotation
PRO_0000185251Add
BLAST

Interactioni

Subunit structurei

Homodimer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi243277.VC2645.

Structurei

3D structure databases

ProteinModelPortaliQ9KNT5.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0624.
KOiK01438.
OMAiADGIHAN.
OrthoDBiEOG60651W.

Family and domain databases

Gene3Di3.30.70.360. 1 hit.
HAMAPiMF_01108. ArgE.
InterProiIPR010169. AcOrn-deacetyl.
IPR001261. ArgE/DapE_CS.
IPR002933. Peptidase_M20.
IPR011650. Peptidase_M20_dimer.
[Graphical view]
PfamiPF07687. M20_dimer. 1 hit.
PF01546. Peptidase_M20. 1 hit.
[Graphical view]
SUPFAMiSSF55031. SSF55031. 1 hit.
TIGRFAMsiTIGR01892. AcOrn-deacetyl. 1 hit.
PROSITEiPS00758. ARGE_DAPE_CPG2_1. 1 hit.
PS00759. ARGE_DAPE_CPG2_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9KNT5-1 [UniParc]FASTAAdd to Basket

« Hide

MPLPSFLEVY EGLISTSSIS STDARWDEGN EQVIAKLADW LSALGFSIQI    50
EQVAPNKQNL IAKLGSGEGG LLLAGHSDTV PFDEGRWNYN PHALTQVNNR 100
FYGLGTADMK GFFAFIYEAV KNVDWSKQTK PLYVLATCDE ETTMLGARHF 150
TENAPFKPDY CIIGEPTSLV PIRAHKGHVA NAIRVTGKSG HSSNPALGVN 200
AIEIMHEVLF ALMQLRDRLI KEYHHPGFEI PTPTLNLGHI HGGDSPNRIC 250
GCCELHYDVR PLPGISLDGL DNLMHDALRE VQQKWPGRIE LVPLHDPIPG 300
YECAHDHPFI HGISEICEQE AQTVNYCTEA PFLQQVCPTL VLGPGSIDQA 350
HQPDEFLAFE FIDPTVRVLS RAMQKYCF 378
Length:378
Mass (Da):41,964
Last modified:October 1, 2000 - v1
Checksum:iF0CC5EC1892ECE8D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE003852 Genomic DNA. Translation: AAF95786.1.
PIRiC82049.
RefSeqiNP_232273.1. NC_002505.1.

Genome annotation databases

EnsemblBacteriaiAAF95786; AAF95786; VC_2645.
GeneIDi2615662.
KEGGivch:VC2645.
PATRICi20084314. VBIVibCho83274_2523.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE003852 Genomic DNA. Translation: AAF95786.1 .
PIRi C82049.
RefSeqi NP_232273.1. NC_002505.1.

3D structure databases

ProteinModelPortali Q9KNT5.
ModBasei Search...

Protein-protein interaction databases

STRINGi 243277.VC2645.

Protein family/group databases

MEROPSi M20.974.

Protocols and materials databases

DNASUi 2615662.
Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAF95786 ; AAF95786 ; VC_2645 .
GeneIDi 2615662.
KEGGi vch:VC2645.
PATRICi 20084314. VBIVibCho83274_2523.

Phylogenomic databases

eggNOGi COG0624.
KOi K01438.
OMAi ADGIHAN.
OrthoDBi EOG60651W.

Enzyme and pathway databases

UniPathwayi UPA00068 ; UER00110 .
BioCyci VCHO:VC2645-MONOMER.

Family and domain databases

Gene3Di 3.30.70.360. 1 hit.
HAMAPi MF_01108. ArgE.
InterProi IPR010169. AcOrn-deacetyl.
IPR001261. ArgE/DapE_CS.
IPR002933. Peptidase_M20.
IPR011650. Peptidase_M20_dimer.
[Graphical view ]
Pfami PF07687. M20_dimer. 1 hit.
PF01546. Peptidase_M20. 1 hit.
[Graphical view ]
SUPFAMi SSF55031. SSF55031. 1 hit.
TIGRFAMsi TIGR01892. AcOrn-deacetyl. 1 hit.
PROSITEi PS00758. ARGE_DAPE_CPG2_1. 1 hit.
PS00759. ARGE_DAPE_CPG2_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 39315 / El Tor Inaba N16961.

Entry informationi

Entry nameiARGE_VIBCH
AccessioniPrimary (citable) accession number: Q9KNT5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 23, 2003
Last sequence update: October 1, 2000
Last modified: May 14, 2014
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. Peptidase families
    Classification of peptidase families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi