Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q9KNT5

- ARGE_VIBCH

UniProt

Q9KNT5 - ARGE_VIBCH

Protein

Acetylornithine deacetylase

Gene

argE

Organism
Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 88 (01 Oct 2014)
      Sequence version 1 (01 Oct 2000)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    N(2)-acetyl-L-ornithine + H2O = acetate + L-ornithine.

    Cofactori

    Binds 2 zinc or cobalt ions per subunit.By similarity
    Glutathione.By similarity

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi76 – 761Cobalt or zinc 1By similarity
    Active sitei78 – 781By similarity
    Metal bindingi108 – 1081Cobalt or zinc 1By similarity
    Metal bindingi108 – 1081Cobalt or zinc 2By similarity
    Active sitei140 – 1401Proton acceptorBy similarity
    Metal bindingi141 – 1411Cobalt or zinc 2By similarity
    Metal bindingi165 – 1651Cobalt or zinc 1By similarity
    Metal bindingi351 – 3511Cobalt or zinc 2By similarity

    GO - Molecular functioni

    1. acetylornithine deacetylase activity Source: TIGR
    2. cobalt ion binding Source: InterPro
    3. metallopeptidase activity Source: InterPro
    4. zinc ion binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. arginine biosynthetic process Source: TIGR

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    Amino-acid biosynthesis, Arginine biosynthesis

    Keywords - Ligandi

    Cobalt, Metal-binding, Zinc

    Enzyme and pathway databases

    BioCyciVCHO:VC2645-MONOMER.
    UniPathwayiUPA00068; UER00110.

    Protein family/group databases

    MEROPSiM20.974.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Acetylornithine deacetylase (EC:3.5.1.16)
    Short name:
    AO
    Short name:
    Acetylornithinase
    Alternative name(s):
    N-acetylornithinase
    Short name:
    NAO
    Gene namesi
    Name:argE
    Ordered Locus Names:VC_2645
    OrganismiVibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
    Taxonomic identifieri243277 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
    ProteomesiUP000000584: Chromosome 1

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 378378Acetylornithine deacetylasePRO_0000185251Add
    BLAST

    Interactioni

    Subunit structurei

    Homodimer.By similarity

    Protein-protein interaction databases

    STRINGi243277.VC2645.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9KNT5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the peptidase M20A family. ArgE subfamily.Curated

    Phylogenomic databases

    eggNOGiCOG0624.
    KOiK01438.
    OMAiADGIHAN.
    OrthoDBiEOG60651W.

    Family and domain databases

    Gene3Di3.30.70.360. 1 hit.
    HAMAPiMF_01108. ArgE.
    InterProiIPR010169. AcOrn-deacetyl.
    IPR001261. ArgE/DapE_CS.
    IPR002933. Peptidase_M20.
    IPR011650. Peptidase_M20_dimer.
    [Graphical view]
    PfamiPF07687. M20_dimer. 1 hit.
    PF01546. Peptidase_M20. 1 hit.
    [Graphical view]
    SUPFAMiSSF55031. SSF55031. 1 hit.
    TIGRFAMsiTIGR01892. AcOrn-deacetyl. 1 hit.
    PROSITEiPS00758. ARGE_DAPE_CPG2_1. 1 hit.
    PS00759. ARGE_DAPE_CPG2_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9KNT5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPLPSFLEVY EGLISTSSIS STDARWDEGN EQVIAKLADW LSALGFSIQI    50
    EQVAPNKQNL IAKLGSGEGG LLLAGHSDTV PFDEGRWNYN PHALTQVNNR 100
    FYGLGTADMK GFFAFIYEAV KNVDWSKQTK PLYVLATCDE ETTMLGARHF 150
    TENAPFKPDY CIIGEPTSLV PIRAHKGHVA NAIRVTGKSG HSSNPALGVN 200
    AIEIMHEVLF ALMQLRDRLI KEYHHPGFEI PTPTLNLGHI HGGDSPNRIC 250
    GCCELHYDVR PLPGISLDGL DNLMHDALRE VQQKWPGRIE LVPLHDPIPG 300
    YECAHDHPFI HGISEICEQE AQTVNYCTEA PFLQQVCPTL VLGPGSIDQA 350
    HQPDEFLAFE FIDPTVRVLS RAMQKYCF 378
    Length:378
    Mass (Da):41,964
    Last modified:October 1, 2000 - v1
    Checksum:iF0CC5EC1892ECE8D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE003852 Genomic DNA. Translation: AAF95786.1.
    PIRiC82049.
    RefSeqiNP_232273.1. NC_002505.1.

    Genome annotation databases

    EnsemblBacteriaiAAF95786; AAF95786; VC_2645.
    GeneIDi2615662.
    KEGGivch:VC2645.
    PATRICi20084314. VBIVibCho83274_2523.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE003852 Genomic DNA. Translation: AAF95786.1 .
    PIRi C82049.
    RefSeqi NP_232273.1. NC_002505.1.

    3D structure databases

    ProteinModelPortali Q9KNT5.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 243277.VC2645.

    Protein family/group databases

    MEROPSi M20.974.

    Protocols and materials databases

    DNASUi 2615662.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAF95786 ; AAF95786 ; VC_2645 .
    GeneIDi 2615662.
    KEGGi vch:VC2645.
    PATRICi 20084314. VBIVibCho83274_2523.

    Phylogenomic databases

    eggNOGi COG0624.
    KOi K01438.
    OMAi ADGIHAN.
    OrthoDBi EOG60651W.

    Enzyme and pathway databases

    UniPathwayi UPA00068 ; UER00110 .
    BioCyci VCHO:VC2645-MONOMER.

    Family and domain databases

    Gene3Di 3.30.70.360. 1 hit.
    HAMAPi MF_01108. ArgE.
    InterProi IPR010169. AcOrn-deacetyl.
    IPR001261. ArgE/DapE_CS.
    IPR002933. Peptidase_M20.
    IPR011650. Peptidase_M20_dimer.
    [Graphical view ]
    Pfami PF07687. M20_dimer. 1 hit.
    PF01546. Peptidase_M20. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55031. SSF55031. 1 hit.
    TIGRFAMsi TIGR01892. AcOrn-deacetyl. 1 hit.
    PROSITEi PS00758. ARGE_DAPE_CPG2_1. 1 hit.
    PS00759. ARGE_DAPE_CPG2_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 39315 / El Tor Inaba N16961.

    Entry informationi

    Entry nameiARGE_VIBCH
    AccessioniPrimary (citable) accession number: Q9KNT5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 23, 2003
    Last sequence update: October 1, 2000
    Last modified: October 1, 2014
    This is version 88 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. Peptidase families
      Classification of peptidase families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3