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Q9KNT4 (CAPP_VIBCH) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase

Short name=PEPC
Short name=PEPCase
EC=4.1.1.31
Gene names
Name:ppc
Ordered Locus Names:VC_2646
OrganismVibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) [Reference proteome] [HAMAP]
Taxonomic identifier243277 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio

Protein attributes

Sequence length876 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_00595

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_00595

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00595

Sequence similarities

Belongs to the PEPCase type 1 family.

Sequence caution

The sequence AAF95787.1 differs from that shown. Reason: Erroneous initiation.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 876876Phosphoenolpyruvate carboxylase HAMAP-Rule MF_00595
PRO_0000166646

Sites

Active site1381 By similarity
Active site5431 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9KNT4 [UniParc].

Last modified November 8, 2002. Version 2.
Checksum: BB7EC7C28CF08B4C

FASTA87698,317
        10         20         30         40         50         60 
MNEKYAALKS NVSMLGRLLG QTIQAADGDV ILAKVETIRK LSKSARAGNQ ADRELLIEEI 

        70         80         90        100        110        120 
KNLPNHQLTP VARAFNQFLN LTNIAEQYHT ISRHCESHVN ELDAIGSLFA KLAQKSVSKF 

       130        140        150        160        170        180 
DTAQAIRDLN IELVLTAHPT EITRRTMINK LVKINECLSK LELSDLSPKE RHKTERRLEQ 

       190        200        210        220        230        240 
LIAQSWHSDV IRQQRPTPLD EAKWGFAVVE NSLWHAVPEF LRELDEQVKS YLGEGLPIDA 

       250        260        270        280        290        300 
RPVHFSSWMG GDRDGNPFVT HTITREVLLL SRWKAADLYL TDINELVSEL SMTKCNEAVR 

       310        320        330        340        350        360 
ALAGEEHEPY RAILKPIRSL LQETIEILDA KLNGQKLAVK APLQTADQLW EPLYACYQSL 

       370        380        390        400        410        420 
HECGMGVIAD GSLLDTLRRI KAFGVHLVRL DVRQESSRHA EVISELTRHL GIGDYNQWSE 

       430        440        450        460        470        480 
QDKIAFLTTE LNSKRPLLPR DWQPSPQVKE VLDTCKIIAA QSKDAFGAYV ISMARTASDV 

       490        500        510        520        530        540 
LAVHLLLQEA GCPYRMDVCP LFETLDDLNN AESVIRQLMN IDLYRGFIQN HQMVMIGYSD 

       550        560        570        580        590        600 
SAKDAGVMAA GWAQYRAMEA LVKVGEEAGI ELTLFHGRGG TIGRGGAPAH AALLSQPPKS 

       610        620        630        640        650        660 
LKGGLRVTEQ GEMIRFKLGL PEVAVNSFNM YASAILEANL LPPPEPKNEW RALMDILSEI 

       670        680        690        700        710        720 
SCNAYRKVVR GEPDFVPYFR QATPELELGK LPLGSRPAKR NPTGGVESLR AIPWIFSWSQ 

       730        740        750        760        770        780 
NRLILPAWLG AGEAIQIAIN EGHQALLEEM CREWPFFSTR LGMLEMVYTK CSVSIACHYD 

       790        800        810        820        830        840 
ERLVEPTLRP LGEKLRAQLQ QDIKVVLNVE NNENLMQSDP WGQESIRLRN IYIEPLNMLQ 

       850        860        870 
AELLYRTRQS ELPAPELEEA LMVTIAGIAA GMRNTG 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE003852 Genomic DNA. Translation: AAF95787.1. Different initiation.
PIRD82049.
RefSeqNP_232274.2. NC_002505.1.

3D structure databases

ProteinModelPortalQ9KNT4.
SMRQ9KNT4. Positions 4-876.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243277.VC2646.

Proteomic databases

PRIDEQ9KNT4.

Protocols and materials databases

DNASU2615663.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAF95787; AAF95787; VC_2646.
GeneID2615663.
KEGGvch:VC2646.
PATRIC20084316. VBIVibCho83274_2524.

Phylogenomic databases

eggNOGCOG2352.
KOK01595.
OMAAIPWVFG.
OrthoDBEOG6TJ7T8.
ProtClustDBPRK00009.

Family and domain databases

HAMAPMF_00595. PEPcase_type1.
InterProIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSPR00150. PEPCARBXLASE.
SUPFAMSSF51621. SSF51621. 1 hit.
PROSITEPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCAPP_VIBCH
AccessionPrimary (citable) accession number: Q9KNT4
Entry history
Integrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: November 8, 2002
Last modified: February 19, 2014
This is version 77 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families