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Q9KNK0 (PCKA_VIBCH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 80. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxykinase [ATP]
Short name=PEP carboxykinase
Short name=PEPCK
EC=4.1.1.49
Alternative name(s):
Phosphoenolpyruvate carboxylase
Gene names
Name:pckA
Ordered Locus Names:VC_2738
OrganismVibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) [Reference proteome] [HAMAP]
Taxonomic identifier243277 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio ›

Protein attributes

Sequence length542 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + oxaloacetate = ADP + phosphoenolpyruvate + CO2. HAMAP-Rule MF_00453

Pathway

Carbohydrate biosynthesis; gluconeogenesis. HAMAP-Rule MF_00453

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00453.

Sequence similarities

Belongs to the phosphoenolpyruvate carboxykinase [ATP] family.

Ontologies

Keywords
   Biological processGluconeogenesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionDecarboxylase
Lyase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from sequence or structural similarity Ref.1. Source: TIGR

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: HAMAP

phosphoenolpyruvate carboxykinase (ATP) activity

Inferred from sequence or structural similarity Ref.1. Source: TIGR

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 542542Phosphoenolpyruvate carboxykinase [ATP] HAMAP-Rule MF_00453
PRO_0000203854

Regions

Nucleotide binding249 – 2568ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9KNK0 [UniParc].

Last modified May 30, 2003. Version 3.
Checksum: 3162609A820D8D14

FASTA54259,844
        10         20         30         40         50         60 
MTVMEHTKAA QIDLAQYGIT GVTELVRNPS YEMLFAEETR SDLEGYERGV VTELGAVAVD 

        70         80         90        100        110        120 
TGIFTGRSPK DKFIVKDDTT RDTLWWTSDK AKNDNKPINQ EVWNDLKALV TKQLSGKRVF 

       130        140        150        160        170        180 
VLDGYCGANA DTRLSVRFIT EVAWQAHFVK NMFIRPSEEE LAHFKPDFVV MNGAKCTNAK 

       190        200        210        220        230        240 
WKEHGLNSEN FTVFNLTERM QLIGGTWYGG EMKKGMFAMM NYFLPLQGIA SMHCSANMGK 

       250        260        270        280        290        300 
AGDVAIFFGL SGTGKTTLST DPKRALIGDD EHGWDDDGVF NFEGGCYAKT IKLSKEAEPD 

       310        320        330        340        350        360 
IYNAIRRDAL LENVTVRSDG SIDFDDGSKT ENTRVSYPIY HIDNIVKPVS KGGHATKVIF 

       370        380        390        400        410        420 
LSADAFGVLP PVSKLTPEQT KYHFLSGFTA KLAGTERGIT EPTPTFSACF GAAFLTLHPT 

       430        440        450        460        470        480 
QYAEVLVKRM EAAGAEAYLV NTGWNGSGKR ISIKDTRGII DAILDGSIEK AETKHIPIFN 

       490        500        510        520        530        540 
LQVPTALPGV DPMILDPRDT YVDPLQWESK AKDLATRFIN NFDKYTDNAE GKALVAAGPK 


LD

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE003852 Genomic DNA. Translation: AAF95877.1.
PIRB82039.
RefSeqNP_232364.1. NC_002505.1.

3D structure databases

ProteinModelPortalQ9KNK0.
SMRQ9KNK0. Positions 13-541.
ModBaseSearch...

Protein-protein interaction databases

STRING243277.VC2738.

Proteomic databases

PRIDEQ9KNK0.

Protocols and materials databases

DNASU2614901.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAF95877; AAF95877; VC_2738.
GeneID2614901.
KEGGvch:VC2738.
PATRIC20084494. VBIVibCho83274_2613.

Phylogenomic databases

eggNOGCOG1866.
KOK01610.
OMATRCAYPI.
ProtClustDBPRK09344.

Enzyme and pathway databases

UniPathwayUPA00138.

Family and domain databases

Gene3D3.40.449.10. 1 hit.
3.90.228.20. 2 hits.
HAMAPMF_00453. PEPCK_ATP.
InterProIPR001272. PEP_carboxykinase_ATP.
IPR013035. PEP_carboxykinase_C.
IPR008210. PEP_carboxykinase_N.
IPR015994. PEPCK_ATP_CS.
[Graphical view]
PfamPF01293. PEPCK_ATP. 1 hit.
[Graphical view]
PIRSFPIRSF006294. PEP_crbxkin. 1 hit.
SUPFAMSSF68923. PEP_carboxykinase_N. 1 hit.
TIGRFAMsTIGR00224. pckA. 1 hit.
PROSITEPS00532. PEPCK_ATP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePCKA_VIBCH
AccessionPrimary (citable) accession number: Q9KNK0
Entry history
Integrated into UniProtKB/Swiss-Prot: September 26, 2001
Last sequence update: May 30, 2003
Last modified: May 1, 2013
This is version 80 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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