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Protein

1,4-alpha-glucan branching enzyme GlgB

Gene

glgB

Organism
Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.UniRule annotation

Catalytic activityi

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.UniRule annotation

Pathwayi: glycogen biosynthesis

This protein is involved in the pathway glycogen biosynthesis, which is part of Glycan biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway glycogen biosynthesis and in Glycan biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei408NucleophileUniRule annotation1
Active sitei461Proton donorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

  • glycogen biosynthetic process Source: TIGR

Keywordsi

Molecular functionGlycosyltransferase, Transferase
Biological processCarbohydrate metabolism, Glycogen biosynthesis, Glycogen metabolism

Enzyme and pathway databases

BioCyciVCHO:VCA0016-MONOMER
UniPathwayiUPA00164

Protein family/group databases

CAZyiCBM48 Carbohydrate-Binding Module Family 48
GH13 Glycoside Hydrolase Family 13

Names & Taxonomyi

Protein namesi
Recommended name:
1,4-alpha-glucan branching enzyme GlgBUniRule annotation (EC:2.4.1.18UniRule annotation)
Alternative name(s):
1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferaseUniRule annotation
Alpha-(1->4)-glucan branching enzymeUniRule annotation
Glycogen branching enzymeUniRule annotation
Short name:
BEUniRule annotation
Gene namesi
Name:glgBUniRule annotation
Ordered Locus Names:VC_A0015/VC_A0016
OrganismiVibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Taxonomic identifieri243277 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
Proteomesi
  • UP000000584 Componenti: Chromosome 2

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001887591 – 7291,4-alpha-glucan branching enzyme GlgBAdd BLAST729

Proteomic databases

PRIDEiQ9KNE8

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi243277.VCA0016

Structurei

3D structure databases

ProteinModelPortaliQ9KNE8
SMRiQ9KNE8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C9C Bacteria
COG0296 LUCA

Family and domain databases

Gene3Di2.60.40.10, 1 hit
2.60.40.1180, 1 hit
HAMAPiMF_00685 GlgB, 1 hit
InterProiView protein in InterPro
IPR006048 A-amylase/branching_C
IPR037439 Branching_enzy
IPR006407 GlgB
IPR006047 Glyco_hydro_13_cat_dom
IPR004193 Glyco_hydro_13_N
IPR013780 Glyco_hydro_b
IPR017853 Glycoside_hydrolase_SF
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
PANTHERiPTHR43651 PTHR43651, 2 hits
PfamiView protein in Pfam
PF00128 Alpha-amylase, 1 hit
PF02806 Alpha-amylase_C, 1 hit
PF02922 CBM_48, 1 hit
PIRSFiPIRSF000463 GlgB, 1 hit
SMARTiView protein in SMART
SM00642 Aamy, 1 hit
SUPFAMiSSF51445 SSF51445, 1 hit
SSF81296 SSF81296, 2 hits
TIGRFAMsiTIGR01515 branching_enzym, 1 hit

Sequencei

Sequence statusi: Complete.

Q9KNE8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKITKKPSKV QQFYDQLARA AFADPFSFLG PYIPAEQGAL RVWMPGADNV
60 70 80 90 100
ALVVEGQARV ALEREGEGGF VLKDGRNLRF THYQLAVDWA GTEQLLDDPY
110 120 130 140 150
QYHGLYAEYE DLHTPKQMYH HMGAQFVTLE RDGKMVSGVR FLVYAPHAAA
160 170 180 190 200
CSLIGAFNHW DGRRHPMQRL DYGIWGIFIP GLPEGTQYKF ELKGPHGEGL
210 220 230 240 250
PHKADPWGFY AEQYPSFASV TYDHRRYQWQ DTAWQQRPVT EKRKQALSFY
260 270 280 290 300
ELHVGSWKRG ENGEFLNYRE LADQLVPYLV EMGYTHVELM PVAEHPFYGS
310 320 330 340 350
WGYQPVGLFA PTSRYGSPDD FKYFVDLCHQ AGIGVVLDWV PAHFPSDSHG
360 370 380 390 400
LANFDGTPLF HDPDPRRGWH QDWNSYIYDL GREHVRRFLV ANALYWFEMF
410 420 430 440 450
HIDGIRVDAV ASMLYLDYSR SHDQWIPNVD GGRENYDAIA TFKWMNEEVY
460 470 480 490 500
KHFPNAMTIA EESTAFPGVS APTFMGGLGF GFKWNMGWMH DSLSYIKEDP
510 520 530 540 550
VHRKYHHNTL TFPLIYAFSE NYVLSLSHDE VVYGKRSLMY KMPGDEWQQT
560 570 580 590 600
ANLRAYLGYM YGQPGKKLNF MGTELGQTAE WDHDGQLQWF LTQFERHAGI
610 620 630 640 650
QRLVRDLNHL YQAQTALHQL DCDPRGFEWR LQDNADLSVI AHERMDEAGN
660 670 680 690 700
RVLVITNFTP VPQQEFRLGV PKTGKYRLLL NTDAKQYNGS DYPVLQDVST
710 720
EAISSEGLDQ SLLLSVPPLA TLFYQWSAK
Length:729
Mass (Da):84,027
Last modified:October 5, 2016 - v2
Checksum:iECDE22002582E543
GO

Sequence cautioni

The sequence AAF95929 differs from that shown. Reason: Frameshift at position 66.Curated
The sequence AAF95930 differs from that shown. Reason: Frameshift at position 66.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE003853 Genomic DNA Translation: AAF95929.1 Frameshift.
AE003853 Genomic DNA Translation: AAF95930.1 Frameshift.
PIRiD82511

Genome annotation databases

EnsemblBacteriaiAAF95929; AAF95929; VC_A0015
AAF95930; AAF95930; VC_A0016

Similar proteinsi

Entry informationi

Entry nameiGLGB_VIBCH
AccessioniPrimary (citable) accession number: Q9KNE8
Secondary accession number(s): Q9KNE9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 15, 2003
Last sequence update: October 5, 2016
Last modified: May 23, 2018
This is version 108 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

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