ID   Q9KKL7_VIBCH            Unreviewed;       568 AA.
AC   Q9KKL7;
DT   01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2000, sequence version 1.
DT   27-MAR-2024, entry version 126.
DE   SubName: Full=Response regulator {ECO:0000313|EMBL:AAF96979.1};
GN   OrderedLocusNames=VC_A1086 {ECO:0000313|EMBL:AAF96979.1};
OS   Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=243277 {ECO:0000313|EMBL:AAF96979.1, ECO:0000313|Proteomes:UP000000584};
RN   [1] {ECO:0000313|EMBL:AAF96979.1, ECO:0000313|Proteomes:UP000000584}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39315 / El Tor Inaba N16961
RC   {ECO:0000313|Proteomes:UP000000584};
RX   PubMed=10952301; DOI=10.1038/35020000;
RA   Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA   Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA   Nelson K.E., Read T.D., Tettelin H., Richardson D., Ermolaeva M.D.,
RA   Vamathevan J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.,
RA   Utterback T., Fleishmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA   Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT   "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT   cholerae.";
RL   Nature 406:477-483(2000).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE003853; AAF96979.1; -; Genomic_DNA.
DR   PIR; C82379; C82379.
DR   RefSeq; NP_233467.1; NC_002506.1.
DR   AlphaFoldDB; Q9KKL7; -.
DR   STRING; 243277.VC_A1086; -.
DR   DNASU; 2612742; -.
DR   EnsemblBacteria; AAF96979; AAF96979; VC_A1086.
DR   KEGG; vch:VC_A1086; -.
DR   PATRIC; fig|243277.26.peg.3691; -.
DR   eggNOG; COG0745; Bacteria.
DR   eggNOG; COG2208; Bacteria.
DR   HOGENOM; CLU_000445_43_7_6; -.
DR   Proteomes; UP000000584; Chromosome 2.
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR   CDD; cd16936; HATPase_RsbW-like; 1.
DR   CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR   Gene3D; 3.40.50.2300; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   PANTHER; PTHR43156:SF13; PROTEIN ICFG; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF13581; HATPase_c_2; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF52172; CheY-like; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   4: Predicted;
KW   Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000584}.
FT   DOMAIN          2..119
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000259|PROSITE:PS50110"
FT   MOD_RES         53
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   568 AA;  64332 MW;  87A02A350D986F51 CRC64;
     MRVMIVDDHG TNRELCRFIL AHIASHIDTF EDGQQAIDAM REMEILPDVI LLDVMMPIKD
     GFVTAKEIRQ AFVKHHIPII FLTVLDDRDS FEKCLALGDD FILKPVERSV LIAKVQAHYR
     IVKMHNEVME QRDELRHFRE QVQYDYAISE SIFTNLMEEM CHQVEHIFGI HYISTPSTIF
     NGDLIVVANR PHGGVYVMIA DATGHGLPAA ISTIPATRTF FSTAQKGLSL GEMVIELNHS
     LERFLPVGMM LAASVFEVRA NGFEISWWGG GLPEAYLLDH HGNIVSRLIS NHMPLGVLPS
     NEFEADVQHF KLEPNQKLVC YTDGIIEAMN EQGEYFGQER LEHVLTKAYS EALIPTLYDA
     VKKFSNRGKG DDLSILTMTF PITNSNSSDK ALPKVVLSCI PLQTELHFPA DVLRKISLMN
     EVRRFLTGIV SGGEDLDLLC SVLSELFANA IEHGLLELDS SLKETPDGFF EFYQLRDKRL
     KTLPEYHWLI LKVNYQPDKQ RIEIDLEHSG KGFDCQALKD ASNQKSYGRG ILLATQLCES
     LEYSNQGRRV TAVYSFARKD TLHYSLPS
//