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Q9KJC4

- ARPR_PSEPU

UniProt

Q9KJC4 - ARPR_PSEPU

Protein

Probable HTH-type transcriptional regulator ArpR

Gene

arpR

Organism
Pseudomonas putida (Arthrobacter siderocapsulatus)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 55 (01 Oct 2014)
      Sequence version 1 (01 Oct 2000)
      Previous versions | rss
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    Functioni

    Probable regulatory protein for the antibiotic efflux pump arpABC operon. May function as a repressor By similarity.By similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    DNA bindingi33 – 5220H-T-H motifPROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW

    GO - Biological processi

    1. regulation of transcription, DNA-templated Source: UniProtKB-KW
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Repressor

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable HTH-type transcriptional regulator ArpR
    Alternative name(s):
    Antibiotic efflux pump ArpABC operon regulator
    Gene namesi
    Name:arpR
    OrganismiPseudomonas putida (Arthrobacter siderocapsulatus)
    Taxonomic identifieri303 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 210210Probable HTH-type transcriptional regulator ArpRPRO_0000070624Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliQ9KJC4.
    SMRiQ9KJC4. Positions 5-210.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini10 – 7061HTH tetR-typePROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 HTH tetR-type DNA-binding domain.PROSITE-ProRule annotation

    Family and domain databases

    Gene3Di1.10.10.60. 2 hits.
    1.10.357.10. 1 hit.
    InterProiIPR023772. DNA-bd_HTH_TetR-type_CS.
    IPR009057. Homeodomain-like.
    IPR001647. HTH_TetR.
    IPR015893. Tet_transcr_reg_TetR-like_C.
    IPR011075. Tet_transcr_reg_TetR-rel_C.
    IPR013572. Tscrpt_reg_MAATS_C.
    [Graphical view]
    PfamiPF08361. TetR_C_2. 1 hit.
    PF00440. TetR_N. 1 hit.
    [Graphical view]
    PRINTSiPR00455. HTHTETR.
    SUPFAMiSSF46689. SSF46689. 1 hit.
    SSF48498. SSF48498. 1 hit.
    PROSITEiPS01081. HTH_TETR_1. 1 hit.
    PS50977. HTH_TETR_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9KJC4-1 [UniParc]FASTAAdd to Basket

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    MVRRTKEEAQ ETRAQIIEAA ERAFYKRGVA RTTLADIAEL AGVTRGAIYW    50
    HFNNKAELVQ ALLDSLHETH DHLARASESE DELDPLGCMR KLLLQVFNEL 100
    VLDARTRRIN EILHHKCEFT DDMCEIRQQR QSAVLDCHKG ITLALANAVR 150
    RGQLPGELDV ERAAVAMFAY VDGLIGRWLL LPDSVDLLGD VEKWVDTGLD 200
    MLRLSPALRK 210
    Length:210
    Mass (Da):23,797
    Last modified:October 1, 2000 - v1
    Checksum:iA167F57269CC2F91
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF183959 Genomic DNA. Translation: AAF73830.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF183959 Genomic DNA. Translation: AAF73830.1 .

    3D structure databases

    ProteinModelPortali Q9KJC4.
    SMRi Q9KJC4. Positions 5-210.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 1.10.10.60. 2 hits.
    1.10.357.10. 1 hit.
    InterProi IPR023772. DNA-bd_HTH_TetR-type_CS.
    IPR009057. Homeodomain-like.
    IPR001647. HTH_TetR.
    IPR015893. Tet_transcr_reg_TetR-like_C.
    IPR011075. Tet_transcr_reg_TetR-rel_C.
    IPR013572. Tscrpt_reg_MAATS_C.
    [Graphical view ]
    Pfami PF08361. TetR_C_2. 1 hit.
    PF00440. TetR_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00455. HTHTETR.
    SUPFAMi SSF46689. SSF46689. 1 hit.
    SSF48498. SSF48498. 1 hit.
    PROSITEi PS01081. HTH_TETR_1. 1 hit.
    PS50977. HTH_TETR_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Identification and molecular characterization of an efflux system involved in Pseudomonas putida S12 multidrug resistance."
      Kieboom J., de Bont J.A.M.
      Microbiology 147:43-51(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 700801 / S12.

    Entry informationi

    Entry nameiARPR_PSEPU
    AccessioniPrimary (citable) accession number: Q9KJC4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 19, 2005
    Last sequence update: October 1, 2000
    Last modified: October 1, 2014
    This is version 55 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3