Q9KIZ5 (Q9KIZ5_SORCE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
EpoF EMBL AAF62885.1

Gene names

Name:

epoF EMBL AAF62885.1

Organism

Sorangium cellulosum (Polyangium cellulosum) EMBL AAF62885.1

Taxonomic identifier

56 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Myxococcales › Sorangiineae › Polyangiaceae › Sorangium

Protein attributes

Sequence length	2439 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Ligand	Phosphopantetheine RuleBase RU000721
Molecular function	Transferase RuleBase RU000693
Gene Ontology (GO)
Biological process	biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	acyl carrier activity Inferred from electronic annotation. Source: InterPro cofactor binding Inferred from electronic annotation. Source: InterPro nucleotide binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity Inferred from electronic annotation. Source: InterPro phosphopantetheine binding Inferred from electronic annotation. Source: InterPro transferase activity, transferring acyl groups other than amino-acyl groups Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9KIZ5 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: D3A972BC49FC3497	FASTA	2,439	257,510
	10 20 30 40 50 60 MATTNAGKLE HALLLMDKLA KKNASLEQER TEPIAIIGIG CRFPGGADTP EAFWELLDSG 70 80 90 100 110 120 RDAVQPLDRR WALVGVHPSE EVPRWAGLLT EAVDGFDAAF FGTSPREARS LDPQQRLLLE 130 140 150 160 170 180 VTWEGLEDAG IAPQSLDGSR TGVFLGACSS DYSHTVAQQR REEQDAYDIT GNTLSVAAGR 190 200 210 220 230 240 LSYTLGLQGP CLTVDTACSS SLVAIHLACR SLRARESDLA LAGGVNMLLS SKTMIMLGRI 250 260 270 280 290 300 QALSPDGHCR TFDASANGFV RGEGCGMVVL KRLSDAQRHG DRIWALIRGS AMNQDGRSTG 310 320 330 340 350 360 LMAPNVLAQE ALLRQALQSA RVDAGAIDYV ETHGTGTSLG DPIEVDALRA VMGPARADGS 370 380 390 400 410 420 RCVLGAVKTN LGHLEGAAGV AGLIKAALAL HHESIPRNLH FHTLNPRIRI EGTALALATE 430 440 450 460 470 480 PVPWPRAGRP RFAGVSAFGL SGTNVHVVLE EAPATVLAPA TPGRSAELLV LSAKSTAALD 490 500 510 520 530 540 AQAARLSAHI AAYPEQGLGD VAFSLVATRS PMEHRLAVAA TSREALRSAL EAAAQGQTPA 550 560 570 580 590 600 GAARGRAASS PGKLAFLFAG QGAQVPGMGR GLWEAWPAFR ETFDRCVTLF DRELHQPLCE 610 620 630 640 650 660 VMWAEPGSSR SSLLDQTAFT QPALFALEYA LAALFRSWGV EPELIAGHSL GELVAACVAG 670 680 690 700 710 720 VFSLEDAVRL VVARGRLMQA LPAGGAMVSI AAPEADVAAA VAPHAASVSI AAVNGPEQVV 730 740 750 760 770 780 IAGAEKFVQQ IAAAFAARGA RTKPLHVSHA FHSPLMDPML EAFRRVTESV TYRRPSMALV 790 800 810 820 830 840 SNLSGKPCTD EVCAPGYWVR HAREAVRFAD GVKALHAAGA GIFVEVGPKP ALLGLLPACL 850 860 870 880 890 900 PDARPVLLPA SRAGRDEAAS ALEALGGFWV VGGSVTWSGV FPSGGRRVPL PTYPWQRERY 910 920 930 940 950 960 WIEAPVDGEA DGIGRAQAGD HPLLGEAFSV STHAGLRLWE TTLDRKRLPW LGEHRAQGEV 970 980 990 1000 1010 1020 VFPGAGYLEM ALSSGAEILG DGPIQVTDVV LIETLTFAGD TAVPVQVVTT EERPGRLRFQ 1030 1040 1050 1060 1070 1080 VASREPGARR ASFRIHARGV LRRVGRAETP ARLNLAALRA RLHAAVPAAA IYGALAEMGL 1090 1100 1110 1120 1130 1140 QYGPALRGLA ELWRGEGEAL GRVRLPESAG SATAYQLHPV LLDACVQMIV GAFADRDEAT 1150 1160 1170 1180 1190 1200 PWAPVEVGSV RLFQRSPGEL WCHARVVSDG QQAPSRWSAD FELMDGTGAV VAEISRLVVE 1210 1220 1230 1240 1250 1260 RLASGVRRRD ADDWFLELDW EPAALEGPKI TAGRWLLLGE GGGLGRSLCS ALKAAGHVVV 1270 1280 1290 1300 1310 1320 HAAGDDTSAA GMRALLANAF DGQAPTAVVH LSSLDGGGQL DPGLGAQGAL DAPRSPDVDA 1330 1340 1350 1360 1370 1380 DALESALMRG CDSVLSLVQA LVGMDLRNAP RLWLLTRGAQ AAAAGDVSVV QAPLLGLGRT 1390 1400 1410 1420 1430 1440 IALEHAELRC ISVDLDPAQP EGEADALLAE LLADDAEEEV ALRGGERFVA RLVHRLPEAQ 1450 1460 1470 1480 1490 1500 RREKIAPAGD RPFRLEIDEP GVLDQLVLRA TGRRAPGPGE VEIAVEAAGL DSIDIQLAVG 1510 1520 1530 1540 1550 1560 VAPNDLPGGE IEPSVLGSEC AGRIVAVGEG VNGLVVGQPV IALAAGVFAT HVTTSATLVL 1570 1580 1590 1600 1610 1620 PRPLGLSATE AAAMPLAYLT AWYALDKVAH LQAGERVLIR AEAGGIGLCA VRWAQRVGAE 1630 1640 1650 1660 1670 1680 VYATADTPEK RAYLESLGVR YVSDSRSGRF AADVHAWTDG EGVDVVLDSL SGEHIDKSLM 1690 1700 1710 1720 1730 1740 VLRACGRLVK LGRRDDCADT QPGLPPLLRN FSFSQVDLRG MMLDQPARIR ALLDELFGLV 1750 1760 1770 1780 1790 1800 AAGAISPLGS GLRVGGSLTP PPVETFPISR AAEAFRRMAQ GQHLGKLVLT LDDPEVRIRA 1810 1820 1830 1840 1850 1860 PAESSVAVRA DGTYLVTGGL GGLGLRVAGW LAERGAGQLV LVGRSGAASA EQRAAVAALE 1870 1880 1890 1900 1910 1920 AHGARVTVAK ADVADRSQIE RVLREVTASG MPLRGVVHAA GLVDDGLLMQ QTPARLRTVM 1930 1940 1950 1960 1970 1980 GPKVQGALHL HTLTREAPLS FFVLYASAAG LFGSPGQGNY AAANAFLDAL SHHRRAHGLP 1990 2000 2010 2020 2030 2040 ALSIDWGMFT EVGMAVAQEN RGARLISRGM RGITPDEGLS ALARLLEGDR VQTGVIPITP 2050 2060 2070 2080 2090 2100 RQWVEFYPAT AASRRLSRLV TTQRAVADRT AGDRDLLEQL ASAEPSARAG LLQDVVRVQV 2110 2120 2130 2140 2150 2160 SHVLRLPEDK IEVDAPLSSM GMDSLMSLEL RNRIEAALGV AAPAALGWTY PTVAAITRWL 2170 2180 2190 2200 2210 2220 LDDALAVRLG GGSDTDESTA SAGSFVHVLR FRPVVKPRAR LFCFHGSGGS PEGFRSWSEK 2230 2240 2250 2260 2270 2280 SEWSDLEIVA MWHDRSLASE DAPGKKYVQE AASLIQHYAD APFALVGFSL GVRFVMGTAV 2290 2300 2310 2320 2330 2340 ELASRSGAPA PLAVFALGGS LISSSEITPE METDIIAKLF FRNAAGFVRS TQQVQADARA 2350 2360 2370 2380 2390 2400 DKVITDTMVA PAPGDSKEPP SKIAVPIVAI AGSDDVIVPP SDVQDLQSRT TERFYMHLLP 2410 2420 2430 GDHEFLVDRG REIMHIVDSH LNPLLAARTT SSGPAFEAK

References

[1]	"Cloning and heterologous expression of the epothilone gene cluster." Tang L., Shah S., Chung L., Carney J., Katz L., Khosla C., Julien B. Science 287:640-642(2000) [PubMed: 10649995] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: SMP44 EMBL AAF62885.1.
[2]	"Isolation and characterization of the epothilone biosynthetic gene cluster from Sorangium cellulosum." Julien B., Shah S., Ziermann R., Goldman R., Katz L., Khosla C. Gene 249:153-160(2000) [PubMed: 10831849] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: SMP44 EMBL AAF62885.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF217189 Genomic DNA. Translation: AAF62885.1.
3D structure databases
HSSP	HSSP built from PDB template 1PQW based on UniProtKB P96202.
ProteinModelPortal	Q9KIZ5.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR001227. Ac_transferase_dom. IPR009081. Acyl_carrier_prot-like. IPR014043. Acyl_transferase. IPR016035. Acyl_Trfase/lysoPLipase. IPR013149. ADH_C. IPR013154. ADH_GroES-like. IPR000794. Beta-ketoacyl_synthase. IPR011032. GroES-like. IPR018201. Ketoacyl_synth_AS. IPR014031. Ketoacyl_synth_C. IPR014030. Ketoacyl_synth_N. IPR016036. Malonyl_transacylase_ACP-bd. IPR016040. NAD(P)-bd_dom. IPR006163. Phsphopanteth-bd. IPR020842. PKS/FAS_KR. IPR020801. PKS_acyl_transferase. IPR020841. PKS_Beta-ketoAc_synthase_dom. IPR020807. PKS_dehydratase. IPR020843. PKS_ER. IPR013968. PKS_KR. IPR020806. PKS_PP-bd. IPR006162. PPantetheine_attach_site. IPR016039. Thiolase-like. IPR016038. Thiolase-like_subgr. [Graphical view]
Gene3D	G3DSA:3.40.366.10. Ac_transferase_reg. 2 hits. G3DSA:1.10.1200.10. ACP_like. 1 hit. G3DSA:3.40.50.720. NAD(P)-bd. 2 hits. G3DSA:3.40.47.10. Thiolase-like_subgr. 2 hits.
PANTHER	PTHR11712. Ketoacyl_synth. 1 hit.
Pfam	PF00698. Acyl_transf_1. 1 hit. PF08240. ADH_N. 1 hit. PF00107. ADH_zinc_N. 1 hit. PF00109. ketoacyl-synt. 1 hit. PF02801. Ketoacyl-synt_C. 1 hit. PF08659. KR. 1 hit. PF00550. PP-binding. 1 hit. [Graphical view]
SMART	SM00827. PKS_AT. 1 hit. SM00826. PKS_DH. 1 hit. SM00829. PKS_ER. 1 hit. SM00822. PKS_KR. 1 hit. SM00825. PKS_KS. 1 hit. SM00823. PKS_PP. 1 hit. [Graphical view]
SUPFAM	SSF52151. Acyl_Trfase/lysoPlipase. 1 hit. SSF50129. GroES_like. 1 hit. SSF55048. Malonyl_transacylase_ACP-bd. 1 hit. SSF53901. Thiolase-like. 1 hit.
PROSITE	PS50075. ACP_DOMAIN. 1 hit. PS00606. B_KETOACYL_SYNTHASE. 1 hit. PS00012. PHOSPHOPANTETHEINE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9KIZ5_SORCE

Accession

Primary (citable) accession number: Q9KIZ5

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2000
Last sequence update:	October 1, 2000
Last modified:	December 14, 2011
This is version 70 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)