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Protein
Submitted name:

Cellulase 12A

Gene

cel12A

Organism
Streptomyces sp. 11AG8
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotation, Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Polysaccharide degradationUniRule annotation

Protein family/group databases

CAZyiCBM2. Carbohydrate-Binding Module Family 2.
GH12. Glycoside Hydrolase Family 12.

Names & Taxonomyi

Protein namesi
Submitted name:
Cellulase 12AImported
Gene namesi
Name:cel12AImported
OrganismiStreptomyces sp. 11AG8Imported
Taxonomic identifieri133452 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 31Sequence analysisAdd BLAST31
ChainiPRO_500432833532 – 371Sequence analysisAdd BLAST340

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi36 ↔ 62Combined sources
Disulfide bondi95 ↔ 100Combined sources

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1OA4X-ray1.50A32-253[»]
ProteinModelPortaliQ9KIH1.
SMRiQ9KIH1.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9KIH1.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini260 – 371CBM2 (carbohydrate binding type-2)InterPro annotationAdd BLAST112

Sequence similaritiesi

Belongs to the glycosyl hydrolase 12 (cellulase H) family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Family and domain databases

Gene3Di2.60.120.180. 1 hit.
2.60.40.290. 1 hit.
InterProiIPR008965. Carb-bd_dom.
IPR001919. CBD2.
IPR012291. CBD_carb-bd_dom.
IPR013320. ConA-like_dom.
IPR013319. GH11/12.
IPR002594. GH12.
[Graphical view]
PfamiPF00553. CBM_2. 1 hit.
PF01670. Glyco_hydro_12. 1 hit.
[Graphical view]
SMARTiSM00637. CBD_II. 1 hit.
[Graphical view]
SUPFAMiSSF49384. SSF49384. 1 hit.
SSF49899. SSF49899. 1 hit.
PROSITEiPS51173. CBM2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9KIH1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRSHPRSATM TVLVVLASLG ALLTAAAPAQ ANQQICDRYG TTTIQDRYVV
60 70 80 90 100
QNNRWGTSAT QCINVTGNGF EITQADGSVP TNGAPKSYPS VYDGCHYGNC
110 120 130 140 150
APRTTLPMRI SSIGSAPSSV SYRYTGNGVY NAAYDIWLDP TPRTNGVNRT
160 170 180 190 200
EIMIWFNRVG PVQPIGSPVG TAHVGGRSWE VWTGSNGSND VISFLAPSAI
210 220 230 240 250
SSWSFDVKDF VDQAVSHGLA TPDWYLTSIQ AGFEPWEGGT GLAVNSFSSA
260 270 280 290 300
VNAGGGNGGT PGTPAACQVS YSTHTWPGGF TVDTTITNTG STPVDGWELD
310 320 330 340 350
FTLPAGHTVT SVWNALISPA SGAVTARSTG SNGRIAANGG TQSFGFQGTS
360 370
SGAGFTAPAG ARLNGTSCTV R
Length:371
Mass (Da):38,481
Last modified:October 1, 2000 - v1
Checksum:i0E1BC4288A148914
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF233376 Genomic DNA. Translation: AAF91283.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF233376 Genomic DNA. Translation: AAF91283.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1OA4X-ray1.50A32-253[»]
ProteinModelPortaliQ9KIH1.
SMRiQ9KIH1.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiCBM2. Carbohydrate-Binding Module Family 2.
GH12. Glycoside Hydrolase Family 12.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiQ9KIH1.

Family and domain databases

Gene3Di2.60.120.180. 1 hit.
2.60.40.290. 1 hit.
InterProiIPR008965. Carb-bd_dom.
IPR001919. CBD2.
IPR012291. CBD_carb-bd_dom.
IPR013320. ConA-like_dom.
IPR013319. GH11/12.
IPR002594. GH12.
[Graphical view]
PfamiPF00553. CBM_2. 1 hit.
PF01670. Glyco_hydro_12. 1 hit.
[Graphical view]
SMARTiSM00637. CBD_II. 1 hit.
[Graphical view]
SUPFAMiSSF49384. SSF49384. 1 hit.
SSF49899. SSF49899. 1 hit.
PROSITEiPS51173. CBM2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9KIH1_9ACTN
AccessioniPrimary (citable) accession number: Q9KIH1
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: November 2, 2016
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.